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A Treatise on Topical Corticosteroids in Dermatology : Use, Misuse and Abuse.

Author: Koushik Lahiri
Publisher: Singapore : Springer Singapore, 2017.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This treatise aims to fill up the lacuna and to contribute significantly to the dissemination of knowledge about the indication/contraindication, mechanism of action, ethical use, side-effects and various other facets related to topical corticosteroid. Topical corticosteroids (TC) have greatly enhanced dermatologists’ ability to effectively treat several difficult dermatoses. The available range of formulations and  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Lahiri, Koushik
A Treatise on Topical Corticosteroids in Dermatology : Use, Misuse and Abuse
Singapore : Springer Singapore,c2017
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Koushik Lahiri
ISBN: 9789811046094 9811046093
OCLC Number: 1001367626
Notes: Description based upon print version of record.
4.2.8 Hand Eczema
Description: 1 online resource (333 p.)
Contents: Foreword; Topical Corticosteroids: The Boon and the Bane; Preface; Acknowledgments; Contents; About the Editor; Biography; Contributors; 1: Evolution and Development of Topical Corticosteroids; 1.1 Introduction; 1.2 The Early Stages: A 'Planned Serendipity'?; 1.3 Early Developments: The Commercial Side; 1.4 The First Topical Use of Corticosteroid: The  War-­Ravaged World Got a Blessing!; 1.5 Fluorinated Agents: An Endeavour for More Potent and Better Activity; 1.6 Betamethasone: A Landmark in the Topical Therapy; 1.7 Further Progress in Topical Therapy: An Effort for Betterment! 1.8 Development of the Assay Methods: Scientific Evaluation Was InevitableReferences; 2: Topical Corticosteroids: Pharmacology; 2.1 Structure-Activity Relationship; 2.2 Potency of Topical Corticosteroids: How to Determine; 2.3 Classification of Topical Corticosteroids; 2.4 Mechanism of Action; 2.5 Pharmacological Actions of Corticosteroids; 2.5.1 Anti-Inflammatory and Immuno-Suppressant Effects; 2.5.2 Vasoconstrictor Action; 2.5.3 Anti-Proliferative Action; 2.6 Therapeutic Indications; 2.7 Formulations; 2.8 Selection and Use of Topical Corticosteroids 2.9 Adverse Drug Reactions (ADRs)2.10 Contraindications; 2.11 Topical Corticosteroids in Special Populations; 2.11.1 Pregnancy and Lactation; 2.11.2 Geriatric and Paediatric Patients; 2.12 Recent Advances; References; 3: Dermatological Indications and Usage of Topical Corticosteroid; 3.1 Introduction; 3.1.1 Structure; 3.1.2 Strength; 3.1.3 Absorption; 3.1.4 Safety in Pregnancy and Breastfeeding; 3.1.5 Vehicles and Preparation; 3.1.6 Combination; 3.1.7 Frequency of Administration and Duration of Treatment; 3.1.8 Occlusion; 3.1.9 Intralesional Administration; 3.1.10 Side Effect 3.2 Indications3.2.1 Atopic Dermatitis; 3.2.2 Seborrhoeic Dermatitis (SD); 3.2.3 Contact Dermatitis (CD); 3.2.4 Photosensitive Eczema; 3.2.5 Lichen Simplex Chronicus (LSC); 3.2.6 Hand Eczema and Pityriasis Alba; 3.2.7 Peristomal Dermatoses; 3.2.8 Psoriasis; 3.2.9 TCS in Children with Psoriasis; 3.2.10 Lichen Planus (LP); 3.2.11 Alopecia Areata (AA); 3.2.12 Vitiligo; 3.2.13 Cutaneous Lupus Erythematosus (CLE); 3.2.14 Blistering Disorders; 3.2.15 Haemangiomas; 3.2.16 Intertrigo and Perianal Inflammation; 3.2.17 Peristomal Inflammation; 3.2.18 Phimosis/Labial Adhesion 3.2.19 Lichen Sclerosus3.2.20 Keloid and Hypertrophic Scars; 3.2.21 Melasma; 3.2.22 Burns; 3.2.23 Chronic Idiopathic Urticaria and Urticaria Pigmentosa; 3.2.24 TCS as Pretreatment; 3.2.25 Granulomatous Diseases; 3.2.26 Sarcoidosis; 3.2.27 Nodulocystic Acne; 3.2.28 Mucocele; References; 4: An Evidence Based Approach of Use of Topical Corticosteroids in Dermatology; 4.1 Introduction; 4.2 Discussion and Evidences; 4.2.1 Eczema; 4.2.2 Vitiligo; 4.2.3 Psoriasis; 4.2.4 Lichen Planus; 4.2.5 Mycosis Fungoides; 4.2.6 Bullous Pemphigoid; 4.2.7 Cutaneous Sarcoidosis

Abstract:

This treatise aims to fill up the lacuna and to contribute significantly to the dissemination of knowledge about the indication/contraindication, mechanism of action, ethical use, side-effects and various other facets related to topical corticosteroid. Topical corticosteroids (TC) have greatly enhanced dermatologists’ ability to effectively treat several difficult dermatoses. The available range of formulations and potencies allows them to flexibly treat all groups of patients, different phases of disease, and different anatomic sites. Improper/incomplete knowledge about topical corticosteroids’ mechanism of action, indications, classifications, and contraindications has produced a rapid rise in the incidence of improper use of these drugs, which could potentially bring disrepute to this entire group of amazing drugs. Responsibility for disseminating proper knowledge regarding when, where, and how to use TC both to internists and patients primarily rests with dermatologists. In this regard, the benefits of rational and ethical use and the potential harm of overuse and misuse for nonmedical, especially cosmetic purposes, should be clearly conveyed before prescribing TC.

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