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TRIM/RBCC proteins

Autor: Germana Meroni
Editora: New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2012.
Séries: Advances in experimental medicine and biology, v. 770.
Edição/Formato   e-book : Documento : InglêsVer todas as edições e formatos
Resumo:
The genomic golden age has delivered the sequence of numerous novel genes while leaving us with many unanswered questions about their function. This is particularly true for gene families as, often, members are annotated based on homology rather than function. The tripartite motif family belonged to this category, although, during the last few years, the field boosted an important wealth of biochemical, cellular and  Ler mais...
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Gênero/Forma: Electronic books
Formato Físico Adicional: Print version:
TRIM/RBCC proteins.
New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2012
(DLC) 2012031700
(OCoLC)805647198
Tipo de Material: Documento, Recurso Internet
Tipo de Documento Recursos de internet, Arquivo de computador
Todos os Autores / Contribuintes: Germana Meroni
ISBN: 9781461453987 1461453984
Número OCLC: 855023001
Descrição: 1 online resource (xix, 145 pages) : illustrations.
Conteúdos: Genomics and evolution of the TRIM gene family / Germana Meroni --
The tripartite motif : structure and function / Lucia Micale [and others] --
TRIM proteins as ring finger E3 ubiquitin ligases / Kazuhiro Ikeda and Satoshi Inoue --
PML nuclear bodies and other TRIM-defined subcellular compartments / Elizabeth C. Batty, Kirsten Jensen, and Paul S. Freemont --
TRIM involvement in transcriptional regulation / Florence Cammas [and others] --
TRIM proteins in cancer / Valeria Cambiaghi [and others] --
TRIM proteins and the innate immune response to viruses / Melvyn W. Yap and Jonathan P. Stoye --
The microtubule-associated C-I subfamily of TRIM proteins and the regulation of polarized cell responses / Timothy C. Cox --
MuRFS : specialized members of the TRIM/RBCC family with roles in the regulation of the trophic state of muscle and its metabolism / Olga Mayans and Siegfried Labeit --
Trim proteins in development / Francesca Petrera and Germana Meroni.
Título da Série: Advances in experimental medicine and biology, v. 770.
Responsabilidade: edited by Germana Meroni.

Resumo:

This book gives an overview of research on the tripartite motif (TRIM, also known as RBCC) family members. It also discusses the physiological and pathological roles of the TRIM.  Ler mais...

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