In this study, two different strategies of rising from a chair were compared, using integrated biomechanical and electromyographic analyses. Nine healthy subjects were instructed to rise using two different strategies: natural sit-to-stand transfer (NSTS) and a sit-to-stand transfer with full flexion of the trunk (FSTS). Sagittal kinematics and ground reaction forces were registered. Muscle activity of nine muscles of the right leg were recorded by means of surface EMG. All signals were synchronized at seat-off. The results show that no differences occur between the kinematics of knee and ankle, whereas the hip flexion is, as expected, higher during FSTS. The higher moment about the knee during NSTS is shifted to proportionally higher moments about the hip and ankle during FSTS. It is mainly the differences in the EMG-levels of the biarticular hip and knee muscles which might explain the differences in net moment. These results are in accordance with a theory about a particular role of biarticular muscles. On the other hand, the shift from knee to ankle cannot be associated with a particular increase in activity of the biarticular m.gastrocnemius. It is hypothesized that about the ankle, control of stability is preferred over movement control. An important conclusion for rehabilitation medicine is that a lower net moment about the knee in FSTS does not automatically imply that this reduces the load on the knee extensors.