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Vaccines, from concept to clinic : a guide to the development and clinical testing of vaccines for human use

Author: Lawrence C Paoletti; Pamela M McInnes
Publisher: Boca Raton, Fla. : CRC Press, ©1999.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

This text examines how a vaccine develops from an idea in a researcher's imagination to the lab bench, through preclinical evaluation and into the clinic for safety and immunogenicity. It provides  Read more...

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Document Type: Book
All Authors / Contributors: Lawrence C Paoletti; Pamela M McInnes
ISBN: 0849311683 9780849311680
OCLC Number: 39236404
Description: 209 pages : illustrations ; 26 cm
Contents: Foreword, G. SiberIdentification of Vaccine Targets, R. Rappuoli and G. Del GiudiceUse of Animals for Vaccine Development, A.B. Onderdonk and R.C. KennedyValidation and Standardization of Serologic Methods for Evaluation of Clinical Immune Response to Vaccines, D.V. Madore, N.M. Strong, and S.A. QuataertConsiderations in the Production of Vaccines for Use in Phase 1 Clinical Trials and Preparation of the Manufacturer's Protocol, L.C. PaolettiHelpful Hints for Preparing an IND Application, M.J. Mattheis and P.M. McInnesIND Application Submissions for Vaccines: Perspectives of IND Reviewers, D.K.F. Chandler, L.D. McVittie, and J.M. Novack Technology Transfer: What You Always Wanted to Know But Were Afraid to Ask, J.A. BiddleDevelopment of a Transmission-Blocking Vaccine: Malaria, Mosquitoes, and Medicine, D.C. KaslowThe Victories and Vexations of Vaccine Production -The Varicella Vaccine, M. Takahashi
Responsibility: edited by Lawrence C. Paoletti and Pamela M. McInnes.
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