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Viruses, cell transformation and cancer

Author: R J A Grand
Publisher: Amsterdam ; London : Elsevier, 2001.
Series: Perspectives in medical virology, v. 5.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Viruses are the agent responsible for perhaps up to one million cases of cancer worldwide each year. Significantly, the study of viruses has also provided important clues to the causes and development of the most common human cancers. This volume presents an account of those viruses which have been directly associated with common human malignancies such as human papillomavirus (HPV), cervical carcinoma, Epstein-Barr  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Viruses, cell transformation and cancer (print)
(DLC) 2001270007
(OCoLC)47149390
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: R J A Grand
ISBN: 0444504966 9780444504968
OCLC Number: 63128376
Description: 1 online resource.
Contents: Introduction. Immortalization of primary rodent cells by SV40 (A. J. Darmon, P. Jat). Adenovirus early region 1 proteins - action through interaction (R. Grand). Polyoma virus middle T-antigen: growth factor receptor mimic (P.R. Nicholson, S.M. Dilworth). Pathobiology of human papillomaviruses (M. Stanley). The function of the human papillomavirus oncogenes (D. Pim, M. Thomas, L. Banks). Hepatitis B virus in experimental carcinogenesis studies (S. Schaefer). Epstein-Barr virus and oncogenesis: from tumors to transforming genes (L. Young). Human Herpes virus 8 (R. Jarrett). Human Herpes virus -deregulation of cell growth and apoptosis (F. Neipel, E. Meinl). Human T-cell leukemia virus type 1 oncoprotein, Tax: Cell cycle dysregulation and cellular transformation (K.G. Low, Kuan-The Jeang). Proviral taggin a strategy using retroviruses to identify oncogenes (T. Moroy, M. Zornig, T. Schmidt). Viruses and apoptosis (E. Hammond, R. Grand). Evasion of the immune system by tumour viruses (E. Blair, N. Phillpot). Immunity to human papilloma viruses: implications for vaccine design (J. Steele). Recombinant adenoviruses in cancer therapy (M. Powell, G. Wilkinson).
Series Title: Perspectives in medical virology, v. 5.
Responsibility: editor, R.J.A. Grand.

Abstract:

Viruses are the agent responsible for perhaps up to one million cases of cancer worldwide each year - their study has provided clues to the causes and development of the most common human cancers.  Read more...

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I. Davis ...is most useful where it describes the mechanisms of interaction of viral gene products with known cellular factors such as those involved in cell cycle regulation. There are intriguing Read more...

 
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