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Vitamin D. Volume 1, Biochemistry, physiology and diagnostics

Author: David Feldman; J Wesley Pike; R Bouillon
Publisher: London ; San Diego, CA : Academic Press is an imprint of Elsevier, [2018] ©2018
Edition/Format:   eBook : Document : English : Fourth editionView all editions and formats
Summary:
"Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Vitamin D.
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: David Feldman; J Wesley Pike; R Bouillon
ISBN: 9780128099667 0128099666
OCLC Number: 1013541228
Notes: Revised edition of: Vitamin D / editor-in-chief, David Feldman ; associate editors, J. Wesley Pike, John S. Adams. 3rd ed. 2011.
Description: 1 online resource (xxxvii, pages) : illustrations (chiefly color), color portraits
Contents: Section I: History, chemistry metabolism, circulation & regulation. Historical overview of vitamin d --
Evolutionary biology: mysteries of vitamin D in fish --
Evolution of human skin color and vitamin D --
Photobiology of vitamin D --
The activating enzymes of vitamin D metabolism (25- and 1[alpha]-hydroxylases) --
CYP24A1: structure, function, and physiological role --
The vitamin D binding protein DBP --
Regulation of renal and extra-renal 1[alpha]-hydroxylase --
Section II. Mechanism of action. Genome-wide perspectives on vitamin D receptor-meditated control of gene expression in target cells --
Diverse mechanisms of transcriptional regulation by the vitamin D receptor --
Structural basis for ligand activity in VDR --
Ligand independent actions of vitamin D receptor --
Vitamin D and chromatin --
Mesenchymal differentiation, epigenetic dynamics, and interactions with VDR --
Vitamin D and microRNAs --
Vitamin D sterol/VDR conformational dynamics and nongenomic actions --
Section III. Mineral and bone homeostasis. Vitamin D regulation of osteoblast function --
Osteoclastogenesis and vitamin D --
Vitamin D activities in osteocytes --
Regulation of intestinal calcium and phosphate absorption --
Calbindin-D28K and calbindin-D9K and the epithelial calcium channels TRPV5 and TRPV6 --
Calcium homeostasis and eggshell biomineralization in female chicken --
Mineralization in mammals --
Cartilage --
Vitamin D and bone: an integrated approach --
Section IV. Extra-skeletal targets. Vitamin D and the kidney --
Vitamin D and the parathyroids --
The calcium-sensing receptor and vitamin d --
Vitamin D in dentoalveolar and oral health --
The role of vitamin D and its receptor in hair follicle biology --
Vitamin D, calcium and the epidermis --
Vitamin D and the cardiovascular system --
Vitamin D brain development and function --
Vitamin D, VDR and adipose tissue: focus on cellular mechanisms --
Vitamin D and skeletal muscle --
Understanding vitamin D from mouse knockout models --
Section V. Human physiology. Pharmacology and pharmacokinetics --
Vitamin D role in the calcium and phosphorus economies --
Fetus, neonate and infant --
Consequences of perinatal vitamin D deficiency on later bone health --
Adolescence and acquisition of peak bone mass --
Pregnancy, lactation, and post-weaning recovery --
Role in reproductive biology and reproductive dysfunction in women --
Vitamin d, reproductive biology, and dysfunction in men --
Vitamin D and the renin-angiotensin system --
Parathyroid hormone, parathyroid hormone-related protein, and calcitonin --
FGF23 counter regulatory hormone for vitamin D actions on mineral metabolism, hemodynamics, and innate immunity --
Section VI. Diagnosis and management. Approach to the patient with metabolic bone disease --
Detection of 1,25-dihydroxyvitamin D in human serum using receptor assisted chemiluminescent hormone assay (REACH) technology --
Mass spectrometry assays of vitamin D metabolites --
Free vitamin d: concepts, assays, outcomes and prospects --
25-hydroxyvitamin D assays: standardization guidelines, problems and interpretation --
Bone histomorphometry --
Radiology of rickets and osteomalcia --
High-resolution imaging techniques for bone quality assessment --
The role of vitamin D in orthopedic surgery --
The IOM-Endocrine Society controversy on recommended vitamin D targets: in support of the IOM Position --
The IOM-Endocrine Society controversy on recommended vitamin D targets: in support of the endocrine society position
Other Titles: Biochemistry, physiology and diagnostics
Vitamin D.
Vitamin D.
Responsibility: editor-in-chief, David Feldman, senior associate editor, J. Wesley Pike, associate editors, Roger Bouillon [and 3 others].

Abstract:

Revised edition of: Vitamin D / editor-in-chief, David Feldman; associate editors, J. Wesley Pike, John S. Adams. 3rd ed. 2011.  Read more...

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