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Smithies, Oliver

Overview
Works: 19 works in 19 publications in 4 languages and 24 library holdings
Genres: Conversation and phrase books  History 
Roles: Author, Interviewee
Publication Timeline
Key
Publications about Oliver Smithies
Publications by Oliver Smithies
Publications by Oliver Smithies, published posthumously.
Most widely held works about Oliver Smithies
 
Most widely held works by Oliver Smithies
The puzzle of diversity by Oliver Smithies( Sound Recording )
in English and held by 5 libraries worldwide
Smithies discusses the problem of doing research in cell differentiation and with antibodies. He also discusses the diversity in light and heacy chains used by antibodies and how antibodies are made
Qing song zou bian jia na da by Qianqian Liu( Book )
1 edition published in 2010 in Chinese and held by 2 libraries worldwide
Po Nobelovi nagradi se mi življenje ni spremenilo by Oliver Smithies( Article )
1 edition published in 2014 in Slovenian and held by 2 libraries worldwide
Two mouse tales by Oliver Smithies( visu )
1 edition published in 2008 in English and held by 1 library worldwide
(CIT): Dr. Oliver Smithies, a 2007 Nobel Laureate in Physiology or Medicine, will look at the progression of ideas that occurred during the 20 years he has spent altering genes in mice, beginning with progress related to the control of blood pressure. He shall emphasize the importance of experimentally controlling the level of expression of genes of interest and the usefulness of developing computer simulations to help understand the results of experiments
Gene transfer by Oliver Smithies( visu )
1 edition published in 1988 in English and held by 1 library worldwide
Segregation of some chromosomal proteins during cell replication by E. F Freedlender( Book )
1 edition published in 1978 in English and held by 1 library worldwide
Nokautowanie genów : w przyszłości będziemy potrafili naprawić wszystkie wady genetyczne by Oliver Smithies( file )
1 edition published in 2007 in Polish and held by 1 library worldwide
The basics : molecular & cellular biology ( visu )
1 edition published in 1996 in English and held by 1 library worldwide
A series of lectures covering general cellular and molecular biology, genetics, and endocrinology, and what can happen when these systems do not function properly
Chromosomal rearrangements and protein structure by Oliver Smithies( Book )
1 edition published in 1964 in English and held by 1 library worldwide
Transforming growth factor beta1 and aldosterone ( file )
1 edition published in 2015 in English and held by 1 library worldwide
Abstract : Purpose of review: It is well established that blocking the renin–angiotensin–aldosterone system (RAAS) is effective for the treatment of cardiovascular and renal complications in hypertension and diabetes mellitus. Although the induction of transforming growth factor beta1 (TGFbeta1) by components of the RAAS mediates the hypertrophic and fibrogenic changes in cardiovascular-renal complications, it is still controversial as to whether TGFbeta1 can be a target to prevent such complications. Here, we review recent findings on the role of TGFbeta1 in fluid homeostasis, focusing on the relationship with aldosterone. Recent findings: TGFbeta1 suppresses the adrenal production of aldosterone and renal tubular sodium reabsorption. We have generated mice with TGFbeta1 mRNA expression graded in five steps, from 10 to 300% of normal, and found that blood pressure and plasma volume are negatively regulated by TGFbeta1. Notably, the 10% hypomorph exhibits primary aldosteronism and sodium and water retention due to markedly impaired urinary excretion of water and electrolytes. Summary: These results identify TGFbeta signalling as an important counterregulatory system against aldosterone. Understanding the molecular mechanisms for the suppressive effects of TGFbeta1 on adrenocortical and renal function may further our understanding of primary aldosteronism, as well as assist in the development of novel therapeutic strategies for hypertension
Immunoglobulin genes : arranged in tandem or in parallel? by Oliver Smithies( Book )
1 edition published in 1974 in English and held by 1 library worldwide
Cell and molecular biology ( visu )
1 edition published in 1995 in English and held by 1 library worldwide
A series of lectures covering general cellular and molecular biology, genetics, and endocrinology, and what can happen when these systems do not function properly
Determination of the zygosit of multiple sets and the twin method by Norma Ford Walker( Book )
1 edition published in 1958 in English and held by 1 library worldwide
The genetic basis of antibody variability by Oliver Smithies( Book )
1 edition published in 1967 in English and held by 1 library worldwide
Molecular basis of human disease by Oliver Smithies( visu )
1 edition published in 1987 in English and held by 0 libraries worldwide
Fifty years as a bench scientist by Oliver Smithies( file )
1 edition published in 2009 in English and held by 0 libraries worldwide
 
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Alternative Names
Oliver Smithies ahli biologi asal Amerika Serikat
Oliver Smithies Amerikaans bioloog
Oliver Smithies amerykański genetyk pochodzenia angielskiego
Oliver Smithies angliai születésű amerikai genetikus
Oliver Smithies brittisk-amerikansk medicinsk forskare
Oliver Smithies genetista inglese
Oliver Smithies US-amerikanischer Genetiker britischer Herkunft
Оливер Смитис
Олівер Смітіз
Олівер Сміціс
Смитис, Оливер
אוליבר סמיתיס
الیور اسمیتیز
آلیور سمتھیز
أوليفر سميثيز
اولیور سمیتھز
ओलिवर स्मिथिस
অলিভার স্মিথ
올리버 스미시스
オリヴァー・スミティーズ
奥利弗·史密斯
Languages
English (16)
Chinese (1)
Slovenian (1)
Polish (1)
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