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Luke, Thomas 1946-

Overview
Works: 11 works in 13 publications in 2 languages and 78 library holdings
Genres: Examinations, questions, etc 
Classifications: PR6062.U43, 823.914
Publication Timeline
Key
Publications about Thomas Luke
Publications by Thomas Luke
Most widely held works about Thomas Luke
 
Most widely held works by Thomas Luke
Condor by Thomas Luke( Book )
2 editions published between 1984 and 1985 in English and held by 27 libraries worldwide
The Hell candidate by Thomas Luke( Book )
2 editions published between 1980 and 1981 in English and held by 16 libraries worldwide
The heirloom by Thomas Luke( Book )
1 edition published in 1982 in English and held by 15 libraries worldwide
Phobia by Thomas Luke( Book )
1 edition published in 1980 in English and held by 12 libraries worldwide
Phobia by Thomas Luke( Book )
1 edition published in 1981 in English and held by 2 libraries worldwide
Study Text in Corporate Secretarial Practice by Luke Thomas( Book )
1 edition published in 2012 in English and held by 1 library worldwide
Kompression und Quantisierung von Wavelet-Koeffizienten by Thomas Luke( Book )
1 edition published in 1997 in Undetermined and held by 1 library worldwide
Boosting of DNA Vaccine-Elicited Gamma Interferon Responses in Humans by Exposure to Malaria Parasites ( file )
1 edition published in 2004 in English and held by 1 library worldwide
A mixture of DNA plasmids expressing five Plasmodium falciparum pre-erythrocyte-stage antigens was administered with or without a DNA plasmid encoding human granulocyte-macrophage colony-stimulating factor (hGM-CSF) as an immune enhancer. After DNA immunization, antigen-specific gamma interferon (IFN-gamma) responses were detected by ELISPOT in 15/31 volunteers to multiple class I- and/or class II-restricted T-cell epitopes derived from all five antigens. Responses to multiple epitopes (less than or equal 7) were detected simultaneously in some volunteers. By 4 weeks after challenge with P. falciparum parasites, 23/31 volunteers had positive IFN- responses and the magnitude of responses was increased from 2- to 143-fold. Nonetheless, none was protected against malaria. Volunteers who received hGM-CSF had a reduced frequency of IFN-gamma responses to class I peptides compared to those who only received plasmids expressing P. falciparum proteins before challenge (3/23 versus 3/8; P=0.15) or after parasite challenge (4/23 versus 5/8; P=0.015) but not to class II peptides before or after challenge. The responses to one antigen (P. falciparum circumsporozoite protein [PfCSP]) were similar among volunteers who received the five-gene mixture compared to volunteers who only received the PfCSP DNA plasmid in a previous study. In summary, DNA-primed IFN-gamma responses were boosted in humans by exposure to native antigen on parasites, coadministration of a plasmid expressing hGM-CSF had a negative effect on boosting of class I-restricted IFN-gamma responses, and there was no evidence that immunization with PfCSP DNA in the mixture reduced T-cell responses to PfCSP compared to when it was administered alone
Fobyah by Thomas Luke( Book )
1 edition published in 1982 in Hebrew and held by 1 library worldwide
Die Grossen Erfolge by Thomas Luke( Sound Recording )
1 edition published in 2010 in No Linguistic Content and held by 1 library worldwide
 
Alternative Names
Languages
English (10)
Hebrew (1)
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