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Davis, Alan R.

Works: 6 works in 8 publications in 1 language and 10 library holdings
Genres: Dissertations, Academic  Conference proceedings  Short stories, American 
Roles: Author
Classifications: KFA2611, 005.369
Publication Timeline
Publications about Alan R Davis
Publications by Alan R Davis
Most widely held works by Alan R Davis
American fiction ( Book )
1 edition published in 1992 in English and held by 2 libraries worldwide
Exempt organizations : a legal guide by Alan Davis( Book )
1 edition published in 2006 in English and held by 2 libraries worldwide
Educational language facility : tutorial manual by Alan Davis( Book )
1 edition published in 1989 in English and held by 1 library worldwide
Validation and characterization of retinoblastoma models and understanding cellular signaling pathways to improve adenoviral vector gene therapy by Wesley Scott Bond( Archival Material )
1 edition published in 2012 in English and held by 1 library worldwide
The Establishment of a Tri-Service Ammunition Demilitarisation Facility by the UK Ministry of Defence ( file )
1 edition published in 1992 in English and held by 0 libraries worldwide
The advent of more stringent environmental legislation and the loss of Crown Immunity from such legislation has forced the Ministry of Defence to adopt a "Green" approach to the demilitarisation of ammunition surpluses. As part of its strategy for the future, the Ministry of Defence (MOD) intends to establish a Tri Service Ammunition Demilitarisation Facility based on rotary kiln incineration technology. This presentation provides an insight into the proposed design of the facility
Cell Therapy to Obtain Spinal Fusion ( file )
3 editions published between 2007 and 2010 in English and held by 0 libraries worldwide
Surgery of the spine to fuse the vertebral bones is one of the most commonly performed operations with an estimated 350,000 Americans undergoing this surgery annually with estimated costs of $60 billion. Current procedures are highly invasive with limited success. The goal of this study is to develop a safe efficacious system for inducing spine fusion which will eliminate the need for invasive surgery. We have currently developed a cell based gene therapy system that can induce rapid bone formation at a targeted location which is independent of immune status of the model. This system relies on adenovirus transduced cells expressing bone morphogenetic protein 2 to induce bone formation leading to vertebral fusion after delivery into the paraspinous musculature. To prolong cell survival and insure cells are maintained at the target site, we have encapsulated them in a non-degradable hydrogel material. This provides additional safety by eliminating direct injection of the virus through cell delivery, and prevention of cell diffusion, through encapsulation. Here we provide preliminary data; demonstrating spine fusion using this system at 6 weeks after induction. This is the first step in demonstrating efficacy, a critical component of preclinical testing. Thus with validation of our hypothesis, this approach can now be developed as a safe and efficacious gene therapy system for spine fusion, thus circumventing the need for costly invasive surgery
English (8)
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