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University of Aberdeen School of Medical Sciences

Overview
Works: 69 works in 97 publications in 1 language and 97 library holdings
Publication Timeline
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Publications about University of Aberdeen
Publications by University of Aberdeen
Most widely held works by University of Aberdeen
Genes, metals and herbal mmedicines : new insights into causes and treatments for Alzheimer's disease by Benjamin David Drever( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
Pharmacogenetic analysis of Farnesyl diphosphate synthase (FPPS) and nitrogen-containing bisphosphonates by Christina Lowes( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
Measurement of dose in diagnostic radiology and the effect of dose reduction on image quality by Nneoyi Onen Egbe( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
The effect of DNA replication on telomere positioning in S. cerevisiae by Hani Ebrahimi( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
Cannabinoid effects on hippocampal neurophysiology and mnemonic processing by Ahushka V Goonawardena( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
From synapse to behaviour : selective modulation of neuronal networks by Thomas Goetz( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
In this thesis, I describe the development of a novel method to selectively modulate neural activity cell-type selectively. Binding of Zolpidem, an allosteric modulator that enhances GABAa receptor function and the inverse agonist [beta]-carboline, require a phenylalanine residue (F77) in the Ύ́2 subunit
The analysis of methylglyoxal detoxification and stress responses in Escherichia coli by Ertan Ozyamak( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
This study assessed the molecular and physiological role of the GlxII-encoding gene (gloB) in E. coli during MG stress. The study emphasises that the degree of KefB and KefC activation is affected by the relative specific activities of GlxI and GlxII via their impact on the SLG molecule. The significance of other genes in protection was poorly understood and this study allowed first insights into the transcriptional response of E. coli to MG stress. ChIPchip studies investigated the genome-wide RNA polymerase distribution of E. coli in response to MG. Furthermore, the contribution of the potassium efflux systems on transcriptional changes was assessed. The data show that E. coli invokes an adaptive transcriptional response that excludes the known key systems for cell survival. The data point to possible novel roles for several other mechanisms known to be involved for example aldehyde detoxification, potassium homeostasis and DNA damage repair
Mechanisms of acid protection mediated by periplasmic chaperones in Escherichia coli by Amanda Harding( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
Molecular studies on fish and plant pathogenic oomycetes by Victoria L Anderson( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
Oomycetes are a class of organisms within which there are a range of devastating pathogens with a variety of different hosts including plants and animals. Phytophthora infestans, the causal agent of late blight in potato, is one of the most important plant pathogens in economical terms. Saprolegnia parasitica is a fish pathogenic oomycete capable of causing disease in freshwater fish species. This study uses both pathogens to work towards understanding the fundamental biology of oomycetes and the development of effective control strategies
The mineralocorticoid receptor amino terminal transactivation domain : investigation of structural plasticity and protein-protein interactions by Katharina Fischer( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
The role of platelets in the activation of TAFI in model thrombi by Karolina M Lisiak( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
Thrombin activatable fibrinolysis inhibitor inhibits fibrinolysis by removing C-terminal lysine residues from partially degraded fibrin. It is expressed by the liver and circulates in plasma as a zymogen TAFI, which can be activated to an active carboxypeptidase, TAFIa, by plasmin or thrombin. Thrombomodulin in complex with thrombin increased the activation 1250-fold. The active carboxypeptidase TAFIa is unstable with a half-life of about 10 min at 37 °C and is inactivated to TAFIai by conformational change
Phylogenetic diversity of fungal stress signaling pathways by Elissavet Nikolaou( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
The adverse consequences of increased ventilation in athletes : effect of age and environment by Claire Bolger( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
Improving biosecurity of bovine in vitro embryo production and cryopreservation by Vanessa Moreira( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
Modelling and simulation of amino acid starvation responses in yeast Saccharomyces cerevisiae by Tao You( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
An in vitro study of the effect of silicon and magnesium ions on bone repair and angiogenesis by Zoe Robertson( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
An investigation of the molecular mechanisms of docetaxel resistance in breast cancer cells by Jay N Sangrithi-Wallace( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
The insulin promoter by Laura A Ferguson( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
The actions of a soft coral derived natural product on neurones by David Woolley( Computer File )
2 editions published in 2008 in English and held by 2 libraries worldwide
The effects of a soft coral derived product and its major active component, 3-carboxyl-methylpyridinium (CMP), were assessed in cultured neurones from dorsal root ganglion (DRG) and the hippocampus, and in hippocampal slices. Application of the soft coral preparation or CMP to cultured DRG neurones reduced an outward potassium current, causing attenuation of spike frequency adaptation. This evoked a switch to multiple firing in previously single firing DRG neurones
The pharmacology of GPR55 and its potential role in cancer by Lesley Ford( Computer File )
2 editions published in 2009 in English and held by 2 libraries worldwide
 
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