WorldCat Identities

Goodfellow, Ian

Works: 18 works in 41 publications in 6 languages and 789 library holdings
Roles: Author
Publication Timeline
Most widely held works by Ian Goodfellow
Deep learning by Ian Goodfellow( Book )

19 editions published between 2016 and 2018 in English and German and held by 718 WorldCat member libraries worldwide

"Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning. The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language processing, speech recognition, computer vision, online recommendation systems, bioinformatics, and video games. Finally, the book offers research perspectives, covering such theoretical topics as linear factor models, autoencoders, representation learning, structured probabilistic models, Monte Carlo methods, the partition function, approximate inference, and deep generative models. Deep Learning can be used by undergraduate or graduate students planning careers in either industry or research, and by software engineers who want to begin using deep learning in their products or platforms. A website offers supplementary material for both readers and instructors"--Page 4 of cover
Deep Learning : das umfassende Handbuch : Grundlagen, aktuelle Verfahren und Algorithmen, neue Forschungsansätze by Ian Goodfellow( Book )

3 editions published in 2018 in German and held by 31 WorldCat member libraries worldwide

L'apprentissage profond by Ian Goodfellow( Book )

1 edition published in 2018 in French and held by 18 WorldCat member libraries worldwide

Le livre de chevet de Elon Musk. Écrit par trois experts dans le domaine, Deep Learning est le seul livre complet sur le sujet. Il fournit une perspective générale et des préliminaires mathématiques indispensables aux ingénieurs en logiciel et aux étudiants qui entrent sur le terrain, et sert de référence aux autorités. Elon Musk, cofondateur et PDG de Tesla et SpaceXstudents L'apprentissage profond (ou deep learning) est un apprentissage automatique qui permet à l'ordinateur d'apprendre par l'expérience et de comprendre le monde en termes de hiérarchie de concepts. Parce que l'ordinateur recueille des connaissances à partir de l'expérience, il n'est pas nécessaire qu'un opérateur humain spécifie formellement toutes les connaissances dont l'ordinateur a besoin. Cet ouvrage présente un large éventail de sujets d'apprentissage profond. Le texte offre un contexte mathématique et conceptuel, théorie des probabilités et théorie de l'information, calcul numérique et apprentissage automatique. Il examine des applications telles que le traitement du langage naturel, la reconnaissance vocale, la vision par ordinateur, les systèmes de recommandation en ligne, la bioinformatique et les jeux vidéo. Deep Learning, sorti fin 2016 aux éditions MIT Press se révèle fondamental pour éclairer de nombreux lecteurs au paradigme informatique et mathématique de l'apprentissage profond (ou deep learning), qui constitue aujourd'hui l'une des composantes fondamentales des intelligences artificielles (IA) dites statistiques et néo-connexionnistes. Son caractère pédagogique en fait un ouvrage de référence dans le monde pour les étudiants, professeurs, ingénieurs, chercheurs de tout domaine et fait l'objet de nombreuses demandes en France, pays épris de tradition mathématique, et dans de nombreux pays et nations francophones accueillant des laboratoires de pointe en intelligence artificielle (tel le Québec). La traduction opérée dans un premier temps par l'intelligence artificielle a été ensuite validée grâce au concours de chercheurs-traducteurs reconnus dans le domaine de l'apprentissage
Shinsō gakushū( Book )

2 editions published in 2018 in Japanese and held by 4 WorldCat member libraries worldwide

Shen du xue xi by Ian Goodfellow( Book )

2 editions published in 2017 in Chinese and held by 4 WorldCat member libraries worldwide

Ben shu fen wei 3 ge bu fen, Di 1 bu fen jie shao ji ben de shu xue gong ju he ji qi xue xi de gai nian, Ta men shi shen du xue xi de yu bei zhi shi;Di 2 bu fen shen ru di jiang jie xian jin yi cheng shu de shen du xue xi fang fa he ji shu;Di 3 bu fen tao lun mou xie ju you qian zhan xing de fang xiang he xiang fa, Ta men bei gong ren wei shi shen du xue xi wei lai de yan jiu zhong dian
Deep learning : systemy uczące się by Ian Goodfellow( Book )

2 editions published in 2018 in Polish and held by 2 WorldCat member libraries worldwide

Norovirus translation and replication by Jia Lu( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Studies on the mechanism of norovirus RNA synthesis by Muhammad Amir Yunus( )

1 edition published in 2012 in English and held by 1 WorldCat member library worldwide

Noroviruses are common pathogens associated with gastroenteritis in humans. As single-stranded positive-sense RNA viruses, noroviruses achieve their genome replication through the synthesis of negative strand RNA intermediates that template the generation of new positive strand RNA genomes. The murine norovirus (MNV) RNA-dependent RNA polymerase (NS7) protein which is a key player in catalysing this process, has been characterised in this study. Tandem affinity purification of MNV NS7 was performed in order to identify host cell factors which interact with the NS7 protein. Proteomic analysis demonstrated that guanosine monophosphate reductase and N(2)- dimethylguanosine tRNA methyltransferase could potentially interact with the MNV NS7. Furthermore, affinity selection of small peptides which specifically bind to the NS7 was carried out by using the phage display technique in an effort to generate peptide inhibitors. Peptide phage with two different conserved motifs and several peptide phage pools with binding activity to the NS7 were successfully identified. However, further cross-binding analysis using ELISA demonstrated that these peptide phage possibly bound non-specifically to the MNV NS7. An optimised RNA based reverse genetics system and reporter-tagged replicon system for MNV were also successfully developed and used to quantify the effects of specific mutations in the MNV genome on viral replication in tissue culture. Using these newly developed systems, the functional role of a small stem loop structure located upstream of the start site of the subgenomic RNA was characterised. This was identified as the potential viral RNA polymerase promoter responsible for subgenomic RNA synthesis. Furthermore, identification and characterisation of this stem loop using mutations suggested the potential involvement of long range RNA-RNA interactions (on negative strand RNA) in regulating the norovirus subgenomic RNA synthesis. Overall, this study has unveiled the importance of protein-protein interactions and RNA-protein interactions in regulating norovirus replication. These interactions could provide interesting targets for antiviral therapeutic intervention in the future
Identification of RNA-protein interactions involved in the norovirus life cycle by Luis Urena Gonzalez( )

1 edition published in 2012 in English and held by 1 WorldCat member library worldwide

Identification and characterisation of an overlapping open reading frame (ORF4) within the murine norovirus genome by Nora Ann McFadden( )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

Caliciviruses are single-stranded positive-sense RNA viruses, most commonly associated with outbreaks of gastroenteritis in humans. In addition to the three open reading frames (ORFs) typical of caliciviruses a highly conserved fourth overlapping ORF within the murine norovirus (MNV) genome was identified and characterised during this project. ORF4 overlaps and is contained within the capsid encoding ORF2 in a +1 frame. Once a suitable antibody had been generated, immunoblotting was used to show that the ORF4 protein is produced during MNV infection. Although ORF4 mutant viruses were viable and replicated to wild-type MNV levels in tissue culture, pressure to restore ORF4 expression upon serial passage under specific conditions was demonstrated. Importantly, the ORF4 knockout virus was significantly attenuated in STAT1-/- mice. Proteomic analysis and a commercial yeast two-hybrid screen were used to identify host cell factors which interact with the ORF4 protein and confocal imaging was employed to examine cellular localisation. These approaches indicated that the ORF4 protein localises to the mitochondria and in vitro assays were subsequently used to demonstrate an involvement of the ORF4 protein in MNV induced apoptosis. As cells infected with the knockout virus showed an earlier and higher degree of apoptosis induction compared to wild-type infected cells, it is possible that the ORF4 protein may function to delay the onset of apoptosis during MNV infection. Whether or not the ORF4 protein has antiapoptotic activity or whether the difference in apoptotic phenotype is an indirect consequence of ORF4 protein function remains to be investigated. These data indicate that the ORF4 protein represents a novel, previously uncharacterised virulence determinant in MNV
A Celtic Tale : the Legend of Deirdre( )

1 edition published in 1996 in English and held by 1 WorldCat member library worldwide

Characterisation of enteric viruses in dogs by Sarah Caddy( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Winter viruses and how to beat them( Visual )

1 edition published in 2013 in English and held by 1 WorldCat member library worldwide

This programme is presented by Alice Roberts and Michael Mosley; it looks at common winter viruses such as the norovirus, influenza and RSV. The set-up is a pop-up laboratory and studio based in London{u2019}s Brunswick Centre, close to Russell Square, then Mosley makes a number of field trips to various laboratories around the UK in order to discover more about these common, but debilitating illnesses. Wendy Barclay, Chair of Influenza Virology at Imperial College, London discusses the severity of RSV, a respiratory illnesses which can affect very young children (she provides expert advice throughout), then Mosley speaks to Dr Jennifer Evans, a paediatrician at the University Hospital, Wales, who is caring for a very poorly 4 week old baby with RSV. There is a real time testing initiative for laboratories to gather data taken from samples regarding viral outbreaks across the country. Dr Catherine Moore, a virologist at Cardiff University Hospital comments. Back in the studio, advice is given about how to tell if you have the common cold or indeed, influenza (if your temperature is above 38 degrees C, then is likely to be flu, below this, a common cold); thermagraphic footage is used to illustrate this. A virus is a microbe and there are many ways in which they insinuate themselves on and into our bodies. Dr Guri Sandhi, an ENT consultant surgeon puts an endoscope up Mosley{u2019}s nose to investigate his nasal passages: the lining of his nose is pink; he does not have a cold. A volunteer with a cold undergoes the same test and mucous (snot) is evident. Next Mosley visits the Derbyshire HEA laboratory to see {u2018}Vomiting Larry{u2019}, invented by Catharine Makinon Booth. They perform an experiment; Larry vomits a liquid with a UV gel present. The virus spreads upwards to 3 metres away. In cleaning the mess up, Mosley reveals exactly how difficult this is to do; he is covered with the UV liquid and, if this was a real virus, would easily be a further source of its spread. Professor Ian Goodfellow, a norovirus researcher from the University of Cambridge, talks about a {u2018}new{u2019} virus, {u2018}Sydney 2012,{u2019} a new mutation {u2013} more people are susceptible to a new virus. In the street, Mosley tries to convince passers-by of the benefits of wearing a face mask; this is to protect people from themselves! Its proven benefit is to physically prevent people introducing the virus up their own noses. In a primary school in Bristol, Professor Andrew Easton, a virologist from the University of Warwick, proves how easy it is for children to act as both reservoirs and spreaders of germs; the children are observed as they interact {u2013} touching their mouths, eyes, noses, hair and clothing, each other and the classroom toys and materials. At the end of the day, under lights which detect the UV sensitive gel, the gel has spread everywhere. The most famous influenza viruses are then mentioned: Spanish Flu in 1918, Asian Flu 1957, Hong Kong Flu 1968 and Swine Flu in 2009 (using a small number of still photographs). Mosley goes to the Animal Health Laboratory in Surrey where he meets Ian Brown, Head of Avian Virology for the Veterinary Laboratories Agency the reasons why birds are such good reservoir for viruses are explained. Mosley is curious to discover if he has had flu this winter by having his blood tested for antibodies present; he visits the Cell Centre and Professor John Oxford, a virologist at Queen Mary College. He finds out that he has not had flu. Alice Roberts exhorts viewers to get themselves immunised if they are one of the at risk groups. Finally, Professor Bill Amos, an Evolutionary Geneticist from the University of Cambridge is asked to answer the question, do men suffer more from flu ie. is there any truth in {u2018}man flu{u2019}? Hormones and stress can contribute to coping with illness and examples in the animal world (red deer are mentioned) indicate that there may be different evolutionary strategies relating to illness and gender
Norovirus replication and attenuation by Lucy Thorne( )

1 edition published in 2013 in English and held by 1 WorldCat member library worldwide

Characterisation of the novel mechanism of protein-directed translation initiation used by caliciviruses by Man Wah Liliane Chung( )

1 edition published in 2012 in English and held by 1 WorldCat member library worldwide

Human noroviruses of the Caliciviridae family are the major cause of acute gastroenteritis in the developed world, but little is known about their molecular mechanisms of translation and replication. Since human noroviruses are not cultivatable in vitro, most molecular studies have therefore been based on the cultivatable murine norovirus (MNV) or feline calicivirus from the Vesivirus genera. Calicivirus translation is dependent on the viral VPg protein covalently linked to the 5' end of viral RNA and removal of the VPg from calicivirus RNA results in loss of infectivity. VPg functions as a 'cap substitute' by interacting with eIF4E to recruit translation initiation factors (eIFs). Given that VPg plays a critical role in the virus life cycle, it is potentially a good anti-viral target. As an initial attempt to identify ways of targeting VPg as an anti-norovirus therapy, we used phage display to identify peptides with an affinity for VPg. Despite repeated attempts however, we failed to generate a peptide that had clear specificity for the calicivirus VPg. Since VPg has ability to bind the cap binding protein eIF4E, m7-GTP Sepharose affinity chromatography was used to isolate eIF4E and the associated VPg. Similar to the analysis of the MNV VPg-translation initiation factor complex, this method successfully isolated not only the human norovirus VPg, but also isolated the entire eIF4F complex and PABP from a cell based-norovirus replicon system. Human norovirus and MNV VPg proteins share 54% amino acid identity and MNV has been proposed as a good model for human norovirus. To begin structural and functional analysis of the human norovirus VPg in the context of an authentic viral life cycle, we introduced the human norovirus VPg into an infectious clone of MNV, to generate a chimera containing all the MNV non-structural and structural proteins but with the human norovirus VPg. Whilst the insertion of the human norovirus VPg into the MNV genome did not affect polyprotein processing, we were unable to recover infectious viral particles. Since the requirement for other cellular factors in the VPg-dependent translation is not fully understood, we used "tandem affinity purification" to further define the components of the initiation factor complex associated with VPg. Our data demonstrated that VPg associates with both canonical initiation factors and possibly non-canonical initiation factors. Further investigation suggested that the scaffold protein eIF4G, which bridges the interaction between PABP and eIF4E, binds directly to VPg via its central domain. To determine the function of eIF4G in the norovirus life cycle, we have silenced eIF4G isoforms in 293T cells using specific siRNAs and transfected them with infectious VPg-linked viral RNA. The siRNA-mediated knockdown of either eIF4G isoform resulted in a 9 fold reduction in virus titre, as well as reduction of viral RNA and protein synthesis, confirming that eIF4G has a functional role in norovirus life cycle. Furthermore, it is not known if the eIF4G-eIF4E interaction is not limiting for MNV translation. Thus, we altered the availability of eIF4E to bind eIF4G by overexpressing wild type or non-phosphorylatable mutant forms of the eIF4E binding protein 1 (4E-BP1) in cells. Overexpression of either the wild type 4E-BP1 or the non-phosphorylatable 4E-BP1 mutant in MNV infected cells showed no significant change in viral RNA, virus titre or protein expression suggesting that the eIF4G-eIF4E interaction in a VPg-translation initiation complex is not limiting for MNV translation. In addition to studying the interaction between VPg and the eIFs, we also examined the effect of mutations in VPg on virus viability and ability to bind the eIF4F complex. A number of mutants were generated in MNV infectious clone to identify residues that play a role in calicivirus translation. The mutational analysis of MNV VPg indicated the C-terminus of VPg is essential for the association of VPg with the components of eIF4F complex and virus viability. This work provides new insights on the interaction between noroviruses and the host cell, as well as the novel mechanisms that viruses use to synthesis their proteins
Deep learning of representations and its application to computer vision by Ian Goodfellow( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Deep learning by Ian Goodfellow( Recording )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Challenges in representation learning: A report on three machine learning contests( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Abstract: The ICML 2013 Workshop on Challenges in Representation Learning 1 focused on three challenges: the black box learning challenge, the facial expression recognition challenge, and the multimodal learning challenge. We describe the datasets created for these challenges and summarize the results of the competitions. We provide suggestions for organizers of future challenges and some comments on what kind of knowledge can be gained from machine learning competitions
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Audience level: 0.63 (from 0.61 for Deep learn ... to 0.98 for Deep learn ...)

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Goodfellow, Ian J. 1987-

Ian Goodfellow

Ian J. Goodfellow datalog ved Google, Stanford, Montreal

Ian J. Goodfellow enxeñeiro informático estadounidense

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伊恩·古德费洛 美国计算机科学家