WorldCat Identities

Chan, Priscilla

Overview
Works: 15 works in 17 publications in 2 languages and 25 library holdings
Roles: Author
Publication Timeline
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Most widely held works about Priscilla Chan
 
Most widely held works by Priscilla Chan
Evolve : Priscilla remaks Priscilla's classics by Priscilla Chan( Recording )

2 editions published in 2015 in Chinese and held by 3 WorldCat member libraries worldwide

Pattern technology : guide to successful blouse pattern by Priscilla Chan( Book )

1 edition published in 2001 in English and held by 3 WorldCat member libraries worldwide

Pattern technology : guide to successful skirt pattern by Priscilla Chan( Book )

1 edition published in 2001 in English and held by 3 WorldCat member libraries worldwide

Welcome back by Priscilla Chan( Recording )

2 editions published between 1995 and 2005 in Chinese and English and held by 2 WorldCat member libraries worldwide

Endoplasmic Reticulum Stress in Mouse Models of Neurodegeneration by Priscilla Chan( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

The endoplasmic reticulum is an organelle that responsible for the folding and processing of newly synthesized proteins. When unfolded or misfolded proteins accumulate in the ER and disrupt proper function this leads to a phenomenon known as ER stress. When this occurs, the UPR is activated in order to reduce ER load and restore the ER to its normal function. ATF6, IRE1, and PERK are the three pathways of the UPR. Here, I studied ER stress and the UPR in relation to retinitis pigmentosa, achromatopsia, and retinal degeneration in a tauopathy mouse model. I found that P23H rhodopsin, which is one of the most common mutated proteins involved with the development of retinitis pigmentosa, is highly ubiquitinated by several E3 ubiquitin ligases in order to be targeted for degradation. In addition, knocking out ATF6 seems to increase activation of IRE1 and preserve rhodopsin levels in the case of Rho+/P23H mice. In the achromatopsia study, Class 2 ATF6 mutants experience constitutive transcriptional activation and Class 3 ATF6 mutants are transcriptionally inactive, which can help explain causation of disease development. In the preliminary studies of the PS19 mouse model, I found that there is retinal degeneration and loss of visual function occurring in these mice compared to their wildtype littermates
By heart by Priscilla Chan( Recording )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Xian ge ya ji by Huixian Chen( Recording )

1 edition published in 2013 in Chinese and held by 1 WorldCat member library worldwide

Back to priscilla 30th anniversary collections by Priscilla Chan( Recording )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Duo xie : Lin Zhenqiang( Recording )

1 edition published in 2003 in Chinese and held by 1 WorldCat member library worldwide

Priscilla chan live 2008 by Priscilla Chan( Recording )

1 edition published in 2008 in English and held by 1 WorldCat member library worldwide

Gui lai ba by Priscilla Chan( Recording )

1 edition published in 2005 in English and held by 1 WorldCat member library worldwide

Before by Priscilla Chan( Recording )

1 edition published in 2000 in Chinese and held by 0 WorldCat member libraries worldwide

[Priscilla Chan] by Priscilla Chan( Recording )

1 edition published in 1997 in Undetermined and held by 0 WorldCat member libraries worldwide

Chen Huixian = Priscilla Chan by Huixian Chen( Recording )

1 edition published in 1997 in Chinese and held by 0 WorldCat member libraries worldwide

 
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Audience Level
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  Kids General Special  
Audience level: 0.66 (from 0.36 for Xian ge ya ... to 1.00 for [Priscilla ...)

Alternative Names
Priscilla Chan Amerikaans kinderarts

Priscilla Chan dokter asal Amerika Serikat

Priscilla Chan pediatra e filántropa estadounidense

Priscilla Chan pediatra i filantropa estatunidenca

Priscilla Chan Pediatra y filántropo estadounidense

Priscilla Chan pédiatre et philanthrope américaine

Πρίσιλα Τσαν

Прісцила Чан

Цукерберг П. 1985-

Чан, Присцилла

Պրիսցիլա Չան

פריסילה צ'אן

بريسيلا تشان طبيبة أطفال أمريكية

پریسیلا چان

प्रिसिला चान

プリシラ・チャン

普莉希拉·陳 美国儿科医生和慈善家

Languages