WorldCat Identities

Braak, Heiko 1937-

Overview
Works: 10 works in 46 publications in 3 languages and 1,557 library holdings
Genres: Scientific atlases 
Roles: Author
Publication Timeline
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Most widely held works by Heiko Braak
Neuroanatomy and pathology of sporadic Parkinson's disease by Heiko Braak( )

18 editions published between 2008 and 2009 in English and held by 848 WorldCat member libraries worldwide

The proteinopathy sporadic Parkinson's disease (sPD) is the second most frequent degenerative disorder of the human nervous system after Alzheimer's disease. The a-synuclein inclusion body pathology (Lewy pathology) associated with sPD is distributed throughout the central, peripheral, and enteric nervous systems. The resulting nonrandom neuronal dysfunction and, in some regions, neuronal loss is reflected by a distinctive topographic distribution pattern of the Lewy pathology that, in the brain, has been staged. Except for olfactory structures and spinal cord constituents of the pain system, sensory components of the nervous system remain uninvolved or virtually intact. The most disease-related damage revolves around motor areas -- particularly around superordinate centers of the limbic and visceromotor systems as well as portions of the somatomotor system. Vulnerable regions are interconnected anatomically and susceptible nerve cell types are not neurotransmitter-dependent. Not all clinical symptoms emerging in the course of sPD can be explained by a lack of dopamine in the nigrostriatal system. These include autonomic dysfunction, pain, hyp- or anosmia, excessive daytime sleepiness, REM sleep behavioral disorder, depression, anxiety, cognitive decline, and dementia. Against the background of the normal morphology and anatomy, the authors analyze the pathoanatomy of sPD in the nervous system at various neuropathological stages and summarize the potential functional consequences of the lesions
Neuroanatomy and pathology of sporadic Alzheimer's disease by Heiko Braak( )

10 editions published between 2014 and 2015 in English and held by 315 WorldCat member libraries worldwide

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Architectonics of the human telencephalic cortex by Heiko Braak( Book )

8 editions published in 1980 in English and German and held by 251 WorldCat member libraries worldwide

This is a timely opus. Most of us now are too young to remember the unpleasant ring of a polemic between those who produced "hair-splitting" parcellations of the cortex (to paraphrase one of O. Vogt's favourite expressions) and those who saw the cortex as a homogeneous matrix sus­ taining the reverberations of EEG waves (to paraphrase Bailey and von Bonin). One camp accused the other of producing bogus preparations with a paint brush, and the other way around the accusation was that of poor eye-sight. Artefacts of various sorts were invoked to explain the opponent's error, ranging from perceptual effects (Mach bands crispening the areal borders) to poor fixation supposedly due to perfusion too soon (!) after death. I have heard most of this directly from the protagonists' mouths. The polemic was not resolved but it has mellowed with age and ultimately faded out. I was relieved to see that Professor Braak elegantly avoids dis­ cussion of an extrememist tenet, that of "hair-sharp" areal boundaries, which makes little sense in developmental biology and is irrelevant to neurophysiology. It was actually detrimental to cortical neuroanatomy, since its negation led to the idea that structurally distinct areas are not at all existent. Yet, nobody would deny the reality of five fingers on one hand even if the detailed assignment of every epidermal cell to one finger or another is obviously impossible
An atlas of Alzheimer's disease( Book )

3 editions published in 1999 in English and held by 134 WorldCat member libraries worldwide

Architectonics of the human telencephalic cortex by Heiko Braak( Book )

1 edition published in 1980 in English and held by 3 WorldCat member libraries worldwide

Neuroanatomy and Pathology of Sporadic Alzheimer's Disease [recurso electrónico] $c by Heiko Braak( )

2 editions published between 2014 and 2015 in English and held by 2 WorldCat member libraries worldwide

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Untersuchungen am Zentralnervensystem von Chimaera monstrosa und Spinax niger by Heiko Braak( Book )

1 edition published in 1964 in German and held by 1 WorldCat member library worldwide

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease by Wolfgang J Streit( )

1 edition published in 2009 in English and held by 1 WorldCat member library worldwide

Atlas de la enfermedad de alzheimer( Book )

1 edition published in 2001 in Spanish and held by 1 WorldCat member library worldwide

Architectonic of human telencephalic cortex by Heiko Braak( Book )

1 edition published in 1980 in English and held by 1 WorldCat member library worldwide

 
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.45 (from 0.34 for Neuroanato ... to 0.96 for Dystrophic ...)

An atlas of Alzheimer's disease Atlas de la enfermedad de alzheimer
Covers
An atlas of Alzheimer's diseaseAtlas de la enfermedad de alzheimer
Alternative Names
Braak, H. 1937-

Heiko Braak deutscher Anatom und Pathologe

Heiko Braak Duits neurowetenschapper

Heiko Braak German anatomist and pathologist

Heiko Braak German scientist

Heiko Braak német neurológus és egyetemi tanár

Heiko Braak tysk professor

ハイコ・ブラーク

海科·布拉克

Languages