WorldCat Identities

Neher, Erwin 1944-

Overview
Works: 66 works in 155 publications in 3 languages and 1,762 library holdings
Genres: History  Conference papers and proceedings  Laboratory manuals 
Roles: Other, Author, Editor, Thesis advisor, Interviewee
Publication Timeline
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Most widely held works about Erwin Neher
 
Most widely held works by Erwin Neher
Single-channel recording by Bert Sakmann( Book )

51 editions published between 1983 and 2013 in 3 languages and held by 1,078 WorldCat member libraries worldwide

Second edition of a reference of techniques in the use of channels and pipettes in the patch clamping process. Includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping
Elektronische Messtechnik in der Physiologie by Erwin Neher( Book )

8 editions published in 1974 in German and held by 76 WorldCat member libraries worldwide

Alexander von Humboldt und Charles Darwin : zwei Revolutionäre wider Willen( Book )

4 editions published in 2011 in German and held by 40 WorldCat member libraries worldwide

Signale steuern unsere Körperfunktionen by Erwin Neher( Book )

2 editions published in 1997 in German and held by 33 WorldCat member libraries worldwide

Klonieren und Charakterisieren von P/Q-Typ-Calciumkanälen für Mikroskopie an lebenden Zellen by Martin Juha( )

2 editions published in 2013 in German and held by 28 WorldCat member libraries worldwide

In all excitable cells voltage-dependent calcium channels can be found. They mediate the entry of calcium into cells following depolarization. Calcium contributes to a wide variety of cellular response like muscle contraction, neurotransmitter release, gene expression and also synaptogenesis. For the neurotransmitter release vesicles are needed and the release is supported from a variety of different proteins. Research in the field of neurotransmitter release revealed the probable existence of two different vesicle populations within the RRP which differ in their release probability, the ve
The role of the presynaptic scaffold protein Bassoon in synaptic transmission at the mouse endbulb of Held synapse by Alejandro Mendoza Schulz( )

2 editions published in 2013 in English and held by 26 WorldCat member libraries worldwide

Endbulbs of Held are large calyceal presynaptic terminals of auditory nerve fibers driving bushy cells in the AVCN. These synapses transmit precisely timed auditory signals up to high frequencies that provide the basis for downstream computation of sound localization and for speech perception (Oertel, 1997, 2005). The underlying molecular mechanisms in these ultrafast processes are largely unknown. The presented study analyzed functional and structural changes upon genetic disruption of bassoon, a large presynaptic scaffold protein in the cytomatrix of the active zone by studying the partia
Stoichiometric Biology of the Synapse by Benjamin Wilhelm( )

2 editions published in 2013 in German and English and held by 25 WorldCat member libraries worldwide

Synaptic xransmission at chemical synapses relies on the fusion of neurotransmitter-loaded vesicles with the plasma membrane of the pre-synaptic terminal (exocytosis). The synaptic vesicle material is then retrieved from the plasma membrane (endocytosis) and new vesicles are formed, completing what has been termed synaptic vesicle recycling. Both exo- and endocytosis are tightly regulated processes, involving a plethora of specific proteins. Much is already known about the nature of these proteins and about their interplay during vesicle recycling. However, this is not sufficient for a glob
Study of synaptic vesicle cycling during exo- and endocytosis using optical approaches by Yunfeng Hua( )

1 edition published in 2012 in English and held by 25 WorldCat member libraries worldwide

Confocal Imaging of Calcium Signal and Exocytosis at Individual Hair Cell Synapses by Aaron Benson Wong( )

2 editions published in 2013 in English and held by 25 WorldCat member libraries worldwide

Hearing over a wide range of sound intensities is thought to require complementary coding by functionally diverse spiral ganglion neurons (SGNs), each changing its firing rate only over a limited sub-range. The means for establishing SGN diversity are not well understood, but likely involves differences among their inputs - the presynaptic active zones (AZs) of inner hair cells (IHCs). In this study, I investigated the Ca2+ signal in IHCs, which were previously demonstrated to be heterogeneous among AZs in mature IHCs. In particular, I explored the changes of synaptic Ca2+ signal during pos
Molekulardynamiksimulationen kraftmikroskopischer Einzelmolekülexperimente by Berthold Heymann( )

2 editions published between 2000 and 2002 in German and held by 25 WorldCat member libraries worldwide

Seit einigen Jahren ist es mit Hilfe verfeinerter experimenteller Techniken möglich, an einzelnen Biomolekülen mechanische Kräfte direkt zu messen. So hat man die Bindungskraft von zahlreichen Protein-Ligand-Komplexen sowie die Elastizität verschiedener Polymermoleküle bestimmt, indem man diese Moleküle mechanisch voneinander getrennt bzw. sie gedehnt und die dazu notwendigen Kräfte registriert hat. In solchen Experimenten hat man allerdings keinen direkten Zugang zu den atomaren Prozessen, die in den Molekülen unter Krafteinwirkung stattfinden
Expression and function of Rab3 interacting molecules and clarin-1 in inner hair cells by Tomoko Oshima-Takago( )

1 edition published in 2013 in English and held by 24 WorldCat member libraries worldwide

Hearing depends on faithful synaptic transmission at the inner hair cell (IHC) ribbon synapse, which is orchestrated by active zone proteins. RIM (Rab3 Interacting Molecules) is one of the active zone proteins and proposed to bind not only with multiple other presynaptic proteins, but also with synaptic vesicles and Ca2+ channels. In this study, the expression pattern and functions of RIMs in the IHCs were examined. Wild type IHCs express RIM2alpha and RIM3gamma at their active zone, whereas RIM1 is the major isoform in the CNS. Further electrophysiological analysis revealed that RIM2alpha
Genetic Targeting and Analysis of Parvalbumin and VGLUT3 Expressing Inhibitory Neurons by Christoph Bredack( )

2 editions published between 2011 and 2012 in English and held by 24 WorldCat member libraries worldwide

Dynamische Eigenschaften von Nervensomamembranen by Erwin Neher( Book )

3 editions published in 1970 in German and held by 24 WorldCat member libraries worldwide

Nerve, muscle, and synapse by Bernard Katz( Book )

5 editions published between 1985 and 1987 in German and held by 18 WorldCat member libraries worldwide

On the mechanisms governing plasma membrane organization - a STED-FCS investigation by Débora Machado Andrade( )

3 editions published between 2013 and 2014 in English and held by 17 WorldCat member libraries worldwide

The plasma membrane is the barrier which localizes and separates life's processes from their external environment. Long described as a free standing two-dimensional fluid mosaic, the organization of the plasma membrane remains elusive. Currently, the most prominent models proposed for its organization lack a consistent body of evidence for their support. Here, we present the first validation of one of these hypotheses: the picket fence model. Using the STED-FCS technique, we demonstrate that cortical actin networks compartmentalize the diffusion of lipids in the plasma membrane of cells. In
Cytoskeletal reorganization in human blood platelets during spreading by Aishwarya Kishore Paknikar( )

2 editions published between 2016 and 2017 in English and held by 16 WorldCat member libraries worldwide

Anucleate, human blood platelets play an important role in haemostasis to prevent excessive blood loss from a vascular damage. Their actin and microtubule (MT) cytoskeleton is especially responsible for bringing about dramatic morphological and biochemical changes in them, which enables the platelets to change their shape, secrete granular contents, aggregate, adhere, spread, and retract in a platelet haemostatic plug, to seal the vascular breach. The platelets are thus extremely important cells from a medical point of view and the study of their cytoskeletal changes is essential. Because p
Nanoscopy inside living brain slices by Nicolai Thomas Urban( )

1 edition published in 2012 in English and held by 16 WorldCat member libraries worldwide

In order to understand how memory is processed and stored in the brain, it would be helpful to observe the ongoing memory processes in action. This is no easy task, however, if it is to be done at the synaptic level. It requires high spatial resolution (preferably in all three dimensions) to observe the synapses in nanoscopic detail, and a fast time resolution (seconds or faster) to observe rapid dynamic processes. On the other hand the method must be noninvasive, so as to not disturb the natural dynamics of the brain and to permit observations over hours or longer without damaging the sens
A post-synaptic forgetting mechanism controlled by synaptotagmin 3 by Ankit Awasthi( )

2 editions published in 2017 in English and held by 16 WorldCat member libraries worldwide

Activity-induced regulation of surface post-synaptic receptor number is a well-known mechanism underlying synaptic plasticity, but the molecular machinery mediating this process is poorly understood. In a screen of synaptotagmin (syt) isoforms, we found that pHluorin-syt3 undergoes Ca2+-dependent endocytosis in hippocampal neurons upon stimulation. Syt3 was present at synapses, and enriched on post-synaptic membranes. Recombinant syt3 pulled down the endocytic protein AP-2 and GluA2, but not GluA1, GluN1, GluN2 or GABAAR1, and also pulled down BRAG2, a protein important for activity-depende
Molecular physiology of synaptic sound encoding at the first auditory synapse by Stefanie Krinner( )

2 editions published in 2017 in English and held by 16 WorldCat member libraries worldwide

To achieve accurate encoding of sounds, inner hair cell (IHC) ribbon-type synapses are highly specialized to release synaptic vesicles (SVs) with high rates and temporal precision. A sophisticated, by far not yet fully disentangled unconventional molecular machinery at the synapse active zone (AZ) realizes this impressive performance. It regulates the number of synaptic CaV1.3 Ca2+-channels, their tight coupling to SVs, and fast re-supply of SVs for sustained rates of exocytosis. Sound-evoked glutamate release from an IHC synapse is sensed by the postsynaptic spiral ganglion neurons (SGNs)
Role of Munc13 Isoforms in Regulating Large Dense Core Vesicle Exocytosis in Chromaffin Cells by Kwun Nok Mimi Man( )

1 edition published in 2015 in English and held by 15 WorldCat member libraries worldwide

The process of vesicular exocytosis is a fast, tightly regulated and Ca2+-triggered event mediated by SNARE complex formation. Although it is known that factors like Munc18, Munc13 and CAPS are important in setting up the SNARE core fusion machinery in a process called priming, the underlying molecular mechanism is not well understood. Munc13 is of critical importance in priming synaptic vesicles (SVs) for release, and SV exocytosis in hippocampal synapses is completely shut down in the absence of Munc13-1 and Munc13-2, whereas in the case of synaptic dense core vesicles (DCVs) the synaptic
 
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Single-channel recording
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Alternative Names
Erwin Neher biofysicus uit Nazi-Duitsland

Erwin Neher deutscher Mediziner und Nobelpreisträger

Erwin Neher fisico tedesco

Erwin Neher German biophysicist

Erwin Neher német biofizikus

Erwin Neher physicien allemand

Erwin Neher tysk professor

Neher, E.

Nejer, E. 1944-

Ервін Неєр

Неер Э.

Неер, Эрвин

Неэр, Эрвин

Эрвин Неер

Эрвін Неер

ארווין נהר ביופיזיקאי גרמני, זוכה פרס נובל

إرفين نيهر

ارون نیہر

اروین نییر

எர்வின் நேயெர்

ఎర్విన్ నెహెర్

에르빈 네어

エルヴィン・ネーアー

厄溫·內爾

Languages
English (70)

German (27)

Italian (1)