WorldCat Identities

Komiyama, Makoto 1947-

Overview
Works: 23 works in 71 publications in 3 languages and 1,356 library holdings
Roles: Author, Editor
Publication Timeline
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Most widely held works by Makoto Komiyama
The bioorganic chemistry of enzymatic catalysis by Myron L Bender( Book )

10 editions published between 1981 and 1984 in English and held by 585 WorldCat member libraries worldwide

Molecular imprinting : from fundamentals to applications by Makoto Komiyama( Book )

14 editions published between 2002 and 2003 in English and held by 371 WorldCat member libraries worldwide

Molecular imprinting, the polymerization of monomers in the presence of a template molecule which imprints structural information into the resulting polymers, is a scientific field which is rapidly gaining significance for a widening range of applications in biotechnology, biochemistry and pharmaceutical research.The methods and tools needed to distinguished target molecules from others by means of tailor-made receptors are constantly growing in importance and complexity. This book gives a concise and highly up-to-date overview of the remarkable progress made in this field in the last five years.The material is comprehensively presented by the authors, giving a thorough insight into fundamentals and applications for researchers in both industry and academy
Cyclodextrin chemistry by Myron L Bender( Book )

15 editions published between 1977 and 1978 in English and Undetermined and held by 338 WorldCat member libraries worldwide

Chemistry was at one time completely described in terms of collision theo­ ry, in which one molecule collided with another, sometimes producing reac­ tion. Then came the realization that enzymes which are highly efficient ca­ talysts, work by way of prior complexation, often stereospecific, which is then followed by chemical reaction. Thus, systems that exhibit "host-guest" relationships, i.e., that show complexing are being looked at an ever in­ creasing frequency. The cyclodextrins are the first and probably the most important example of compounds that exhibits complex formation. This is a book about the cyclodextrins. There are of course other compounds that exhibit "host-guest" relationships and thus bind other organic molecules, but so far they have not achieved the importance of the cyclodextrins. By their name it is obvious that cyclodextrins are cyclic compounds. The complexes that they form are therefore cyclic inclusion complexes. Because the complexes are cyclic in nature, complexation can be very strong, as op­ posed to 1t-complex, electrostatic, or apolar complexes in which complex formation is two-dimensional rather than three-dimensional. Cyclodextrins turn out to be excellent models of enzymes. This is proba­ bly not fortuitous because they were first sought since it was discovered that the principal binding in the enzyme chymotrypsin was a cyclic inclusion complex. Cyclodextrins can do more than form cyclic inclusion complexes, they can catalyze as well. But catalysis always occurs after complex formation
Cyclodextrin chemistry ; with 37 tables by Myron L Bender( Book )

1 edition published in 1978 in English and held by 18 WorldCat member libraries worldwide

Seibutsu yūki kagaku : Kemikaru baiorojī eno tenkai by Makoto Komiyama( Book )

4 editions published between 1988 and 2004 in Japanese and held by 8 WorldCat member libraries worldwide

Kōso riyō gijutsu taikei : Kiso kaiseki kara kaihen takinōka sangyō riyō made( Book )

3 editions published in 2010 in Japanese and held by 5 WorldCat member libraries worldwide

Seimei kagaku gairon( Book )

2 editions published in 1997 in Japanese and held by 5 WorldCat member libraries worldwide

Shikurodekisutorin no oyo gijutsu( Book )

3 editions published between 2008 and 2013 in Japanese and held by 5 WorldCat member libraries worldwide

The Bioorganic Chemistry of Enzymatic Catalysis by ML BENDER( )

3 editions published in 1984 in English and held by 3 WorldCat member libraries worldwide

Chao fen zi hua xue by F Vögtle( Book )

1 edition published in 1995 in Japanese and held by 2 WorldCat member libraries worldwide

Tennen koso to jinko koso by Makoto Komiyama( Book )

1 edition published in 1996 in Japanese and held by 2 WorldCat member libraries worldwide

Bunshi ninshiki to seitai kinō( Book )

2 editions published in 1989 in Japanese and held by 2 WorldCat member libraries worldwide

Bunseki kagaku( Book )

1 edition published in 2002 in Japanese and held by 2 WorldCat member libraries worldwide

Shikurodekisutorin no kagaku( Book )

2 editions published in 1979 in Japanese and held by 2 WorldCat member libraries worldwide

Seimei kagaku( Book )

1 edition published in 1996 in Japanese and held by 1 WorldCat member library worldwide

Bioorganičeskaâ himiâ fermentativnogo kataliza by Myron L Bender( Book )

1 edition published in 1987 in Russian and held by 1 WorldCat member library worldwide

Seimei kagaku( Book )

1 edition published in 2011 in Japanese and held by 1 WorldCat member library worldwide

Inhibition of nonenzymatic depurination of nucleic acids by polycations( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : DNA base depurination is one of the most common forms of DNA damage in vivo and in vitro, and the suppression of depurination is very important for versatile applications of DNA in biotechnology and medicine. In this work, it was shown that the polycations chitosan (Cho) and spermine (Spm) strongly inhibit DNA depurination through the formation of polyion complexes with DNA molecules. The intramolecular electrostatic interaction of positively charged polycations with DNA efficiently suppresses the protonation of purine groups, which is the key step of depurination. Importantly, the optimal pH for Cho's inhibition of depurination is significantly different from that of Spm. Cho is very effective in the inhibition of depurination in highly acidic media (pH: 1.5-3), whereas Spm is found to suppress the chemical reaction near neutral pH, as well as in acidic solutions. This remarkable pH specificity of the two biorelevant polycations is attributed to the difference in the pK a values of the amino groups. The relevance of our results with the biological roles of biogenic polycations is also discussed. Abstract : The suppression of depurination is crucially important for versatile applications of DNA. Here, we show that the polycations chitosan (Cho) and spermine (Spm) strongly inhibit DNA depurination through the formation of polyion complexes with DNA molecules. Also, the optimal pH for Cho's inhibition of depurination is significantly different from that of Spm
Erubīmaku( Book )

1 edition published in 1990 in Japanese and held by 1 WorldCat member library worldwide

Seimei kagaku by Makoto Komiyama( Book )

1 edition published in 1996 in Japanese and held by 1 WorldCat member library worldwide

 
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Audience level: 0.57 (from 0.48 for The bioorg ... to 0.97 for Erubīmaku ...)

The bioorganic chemistry of enzymatic catalysis
Covers
Molecular imprinting : from fundamentals to applications
Alternative Names
Komiâma, M.

Komiâma, Makoto.

Komiyama, M.

Komiyama, Makoto

Komiyama, Makoto 1947-

M. Komiyama

M. コミヤマ

Комияма, М 1947-

Комияма, Макото

コミヤマ, マコト

コミヤマ, マコト 1947-

小宮山, 眞

小宮山眞

小宮山真 1947-

Languages