WorldCat Identities

利根川進 1939-

Overview
Works: 27 works in 39 publications in 6 languages and 98 library holdings
Genres: Biography 
Roles: Author, Other
Publication Timeline
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Most widely held works by 利根川進
Seishin to busshitsu : bunshi seibutsugaku wa doko made seimei no nazo o tokeru ka by Takashi Tachibana( Book )

5 editions published between 1990 and 1993 in Japanese and held by 28 WorldCat member libraries worldwide

Watakushi no nō kagaku kōgi( Book )

2 editions published in 2001 in Japanese and held by 8 WorldCat member libraries worldwide

Nō no nakami ga mietekita( Book )

2 editions published in 2004 in Japanese and held by 6 WorldCat member libraries worldwide

Seimei ni idomu : Tonegawa Susumu, Hanabusa Hidesaburō no sekai( Book )

2 editions published in 1988 in Japanese and held by 5 WorldCat member libraries worldwide

Genetic transcription of phage [Lambda] by Susumu Tonegawa( )

3 editions published in 1968 in English and held by 4 WorldCat member libraries worldwide

Cloning of Immunoglobulin genes = Klonierung von Immunoglobulin-Genen by Susumu Tonegawa( Book )

1 edition published in 1978 in German and held by 3 WorldCat member libraries worldwide

Busshitsu to kokoro : No to uchinaru kokoro no kankei o sagasu futari no noberusho jushosha ni yoru taiwa( Book )

1 edition published in 2016 in Japanese and held by 2 WorldCat member libraries worldwide

Transcription of the SV40 genome in transformed cells and during lytic infection by Susumu Tonegawa( Book )

1 edition published in 1970 in English and held by 1 WorldCat member library worldwide

Sōzō e no chōsen : Tonegawa Susumu no sekai = Challenge for creation by Susumu Tonegawa( Book )

1 edition published in 1989 in Japanese and held by 1 WorldCat member library worldwide

Memory mechanisms by Susumu Tonegawa( Visual )

1 edition published in 1998 in English and held by 1 WorldCat member library worldwide

1987 Nobel Prize winner Susumu Tonegawa, a molecular biologist by training, presents his work on the molecular and cellular basis of memory formation
Somatic reorganization of immunoglobulin genes during lymphocyte differentiation by Susumu Tonegawa( Book )

1 edition published in 1981 in English and held by 1 WorldCat member library worldwide

Manipulating memory in space and time( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Highlights: Identification and manipulations of memory engrams and engram cells. Creating false memory by manipulating engram cells. Countering depression-like behaviors by stimulating positive valence engram cells. Restoring memory in early Alzheimer's mouse models by engineering engram cells. Abstract : One of the most fascinating aspects of an animal's brain is its ability to acquire new information from experience and retain this information over time as memory. The search for physical correlates of memory, the memory engram, has been a longstanding endeavor in modern neurobiology. Recent advances in transgenic and optogenetic tools have enabled the identification, visualization, and manipulations of natural, sensory-evoked, engram cells for a specific memory residing in specific brain regions. These studies are paving the way not only to understand memory mechanisms in unprecedented detail, but also to repair the abnormal state of mind associated with memory by engineering
Moléculas del sistema inmunitario by Susumu Tonegawa( Book )

1 edition published in 1985 in Spanish and held by 1 WorldCat member library worldwide

Organization of immunoglobulin genes by Susumu Tonegawa( Book )

1 edition published in 1978 in English and held by 1 WorldCat member library worldwide

Kokusai shakai to nihon no shoho sen( Visual )

in Japanese and held by 1 WorldCat member library worldwide

Somatic changes in the content and context of immunoglobulin genes by Susumu Tonegawa( Book )

1 edition published in 1977 in English and held by 1 WorldCat member library worldwide

Nobelpriset i fysiologi eller medicin. för hans upptäckt av "det genetiska underlaget för uppkomsten av antikroppars variationsrikedom."( Book )

1 edition published in 1987 in Swedish and held by 1 WorldCat member library worldwide

Molecular and circulatory mechanisms for hippocampus dependent memory by Susumu Tonegawa( Visual )

1 edition published in 2005 in English and held by 1 WorldCat member library worldwide

Direct excitation of parvalbumin‐positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Abstract Key points Parvalbumin‐containing (PV) neurons from mouse CA1 hippocampus (HC) and prefrontal cortex exhibit a fast spiking phenotype in vitro. Within CA1, HC PV cells are mainly comprised of basket and bistratified cell types. Direct activation of muscarinic acetylcholine receptors (mAChRs) enhances excitability more in CA1 HC than in prefrontal cortex PV cells. mAChR‐induced excitation of CA1 PV cells occurs through direct activation of M1 mAChRs. Transgenetic deletion of M1 mAChRs from PV cells diminishes M1 mAChR expression and cholinergic excitation of CA1 PV cells. mAChR‐induced excitation exclusively in PV cells enhances GABAergic transmission in CA1 pyramidal cells. In vivo activation of M1 mAChRs in PV cells is important in recognition and working memory but not spatial memory. Abstract Parvalbumin‐containing (PV) neurons, a major class of GABAergic interneurons, are essential circuit elements of learning networks. As levels of acetylcholine rise during active learning tasks, PV neurons become increasingly engaged in network dynamics. Conversely, impairment of either cholinergic or PV interneuron function induces learning deficits. Here, we examined PV interneurons in hippocampus (HC) and prefrontal cortex (PFC) and their modulation by muscarinic acetylcholine receptors (mAChRs). HC PV cells, visualized by crossing PV‐CRE mice with Rosa26YFP mice, were anatomically identified as basket cells and PV bistratified cells in the stratum pyramidale; in stratum oriens, HC PV cells were electrophysiologically distinct from somatostatin‐containing cells. With glutamatergic transmission pharmacologically blocked, mAChR activation enhanced PV cell excitability in both CA1 HC and PFC; however, CA1 HC PV cells exhibited a stronger postsynaptic depolarization than PFC PV cells. To delete M1 mAChRs genetically from PV interneurons, we created PV‐M1 knockout mice by crossing PV‐CRE and floxed M1 mice. The elimination of M1 mAChRs from PV cells diminished M1 mAChR immunoreactivity and muscarinic excitation of HC PV cells. Selective cholinergic activation of HC PV interneurons using Designer Receptors Exclusively Activated by Designer Drugs technology enhanced the frequency and amplitude of inhibitory synaptic currents in CA1 pyramidal cells. Finally, relative to wild‐type controls, PV‐M1 knockout mice exhibited impaired novel object recognition and, to a lesser extent, impaired spatial working memory, but reference memory remained intact. Therefore, the direct activation of M1 mAChRs on PV cells contributes to some forms of learning and memory
Lezioni a Stoccolma: l' origine somatica della diversità immunitaria by Susumu Tonegawa( )

in Italian and held by 1 WorldCat member library worldwide

 
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Alternative Names
Donegawa, Seuseumu 1939-

Susumu Tonegava

Susumu Tonegawa

Susumu Tonegawa biologo giapponese

Susumu Tonegawa dokter asal Jepang

Susumu Tonegawa Japanese biologist

Susumu Tonegawa Japans moleculair bioloog

Susumu Tonegawa japoński biochemik, noblista

Susumu Tonegawa japonský molekulární biolog

Susumu Tonegawa scientifique japonais

Tonegava Szuszumu japán biológus

Tonegawa, Susuma 1939-

Tonegawa, Susumu.

Tonegawa, Susumu 1939-

Tonegawa Susumu japanischer Molekularbiologe

Судзуми Тонегава

Сусуму Танегава

Сусуму Тонегава

Тонегава, Судзуми

Тонеґава Сусуму

סוסומו טונגאווה

سسوموٹونیگوا

سوسومو تونيغاوا

سوسومو تونگاوا

سوسومو ٹونیگاوا

সুসুমু তোনেগাওয়া

도네가와 스스무

도네가와 스스무 일본의 분자생물학자

리근천진 1939-

이근천진 1939-

토네가와 스스무 1939-

とねがわ すすむ 1939-

トネガワ, ススム

トネガワ, ススム 1939-

利根川進 1939-

利根川進 日本の生物学者

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