WorldCat Identities

Mikoshiba, Katsuhiko 1945-

Overview
Works: 37 works in 86 publications in 2 languages and 865 library holdings
Genres: Conference papers and proceedings  Handbooks and manuals 
Roles: Author, Editor, Other
Publication Timeline
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Most widely held works by Katsuhiko Mikoshiba
Handbook of neurochemistry and molecular neurobiology by Abel Lajtha( )

17 editions published in 2009 in English and held by 442 WorldCat member libraries worldwide

This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics. Particular attention is given to function and trafficking of membrane proteins including various ion channels, aquaporines, gap junctions
Molecular basis of ion channels and receptors involved in nerve excitation, synaptic transmission and muscle contraction : in memory of Professor Shosaku Numa( Book )

16 editions published in 1993 in English and held by 290 WorldCat member libraries worldwide

This volume contains the proceedings of the first conference of the New York Academy of Sciences to be held in Japan. This conference took place at the Ibuka Memorial Hall of Waseda University, one of the oldest universities in Tokyo, and was organized in part by a group of researchers who were supported by the Grant-in-Aid for Scientific Research in the Priority Area of 'Impulse signaling, ' from the Japanese Ministry of Education, Science and Culture. The aim of the conference was to summarize recent advances in our understanding of signal transduction, from the receptors and effectors in this case the various ion channels of neurons, smooth or striated muscle cells, endocrine cells and other tissues. Molecular, Receptors, Nerve, BD, Conference, RA IV
Application of genetically encoded indicators to mammalian central nervous system by Katsuhiko Mikoshiba( Book )

3 editions published in 2016 in English and held by 29 WorldCat member libraries worldwide

Genetically encoded indicators emerged as promising tools for cell type-specific and chronic recording of neuronal population activity. Since publication of the first prototypical genetically encoded Ca2+ indicators (Cameleons) in 1997, we have witnessed remarkable evolution of the field, with rapid improvement of indicator performance as well as expanded application to many model organisms in the neuroscience community. Challenges still remain, however, concerning the mammalian central nervous system: limited sensitivity of indicators to subtle changes in activity, slow signal kinetics, cytotoxicity after a long-term and high-level expression of indicators, and variable performance across cell types. In addition to improvement of the indicators per se, development of strategies that allow combined use of the indicators and optogenetic tools is also desired. In this Research Topic, we recruited top researchers in the field and their young colleagues to present their cutting-edge research as well as insightful opinions on the following subtopics:1) Latest breakthroughs on development of genetically encoded indicators2) Novel scientific findings obtained with genetically encoded indicators3) Wishlist for the next-generation genetically encoded indicators4) Guideline for selecting an appropriate indicator5) Optimal methodology for indicator delivery to mammalian CNS
Coincidence detection in the nervous system : molecular and cellular mechanisms, consequence for learning and memory by Human Frontier Science Program( Book )

1 edition published in 1996 in English and held by 25 WorldCat member libraries worldwide

Handbook of Neurochemistry and Molecular Neurobiology Neural Signaling Mechanisms by Abel Lajtha( )

3 editions published in 2009 in English and Undetermined and held by 12 WorldCat member libraries worldwide

No no hassei bunka kasosei( Book )

2 editions published in 2002 in Japanese and held by 5 WorldCat member libraries worldwide

Jikken igaku no genri = Principes de medecine experimentale by Claude Bernard( Book )

3 editions published in 2008 in Japanese and held by 5 WorldCat member libraries worldwide

Coincidence detection in the nervous system by Human Frontier Workshop( Book )

1 edition published in 1996 in English and held by 5 WorldCat member libraries worldwide

Kankaku kikan to nōnai jōhō shori( Book )

1 edition published in 2002 in Japanese and held by 5 WorldCat member libraries worldwide

Shinkeikei no keisei to tōgō( Book )

2 editions published in 1991 in Japanese and held by 4 WorldCat member libraries worldwide

Nō shinkei kenkyū nisen shi : shinkei hassei kasosei to kōjinō kinō no mekanizumu soshite nō shinkei shikkan no bunshi kikō no kaimei e( Book )

4 editions published in 2003 in Japanese and held by 4 WorldCat member libraries worldwide

Nōshinkei( Book )

3 editions published in 1997 in Japanese and held by 4 WorldCat member libraries worldwide

Nyūron no seirigaku( Book )

2 editions published in 2009 in Japanese and held by 4 WorldCat member libraries worldwide

Bunshi shinkei seibutsugaku( Book )

2 editions published in 1989 in Japanese and held by 3 WorldCat member libraries worldwide

Nō shinkei kenkyū purotokōru( Book )

2 editions published in 1995 in Japanese and held by 3 WorldCat member libraries worldwide

Karushiumu ion to shigunaru dentatsu( Book )

3 editions published between 1998 and 2000 in Japanese and held by 3 WorldCat member libraries worldwide

Kankaku kikan to nōnai jōhō shori( Book )

1 edition published in 2002 in Japanese and held by 2 WorldCat member libraries worldwide

Kimera no saibō shakaigaku( Book )

1 edition published in 1982 in Japanese and held by 2 WorldCat member libraries worldwide

Rearing-environment-dependent hippocampal local field potential differences in wild-type and inositol trisphosphate receptor type 2 knockout mice( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract : Key points: Mice reared in an enriched environment are demonstrated to have larger hippocampal gamma oscillations than those reared in isolation, thereby confirming previous observations in rats. To test whether astrocytic Ca 2+ surges are involved in this experience-dependent LFP pattern modulation, we used inositol trisphosphate receptor type 2 (IP3 R2)-knockout (KO) mice, in which IP3 /Ca 2+ signalling in astrocytes is largely diminished. We found that this experience-dependent gamma power alteration persists in the KO mice. Interestingly, hippocampal ripple events, the synchronized events critical for memory consolidation, are reduced in magnitude and frequency by both isolated rearing and IP3 R2 deficiency. Abstract: Rearing in an enriched environment (ENR) is known to enhance cognitive and memory abilities in rodents, whereas social isolation (ISO) induces depression-like behaviour. The hippocampus has been documented to undergo morphological and functional changes depending on these rearing environments. For example, rearing condition during juvenility alters CA1 stratum radiatum gamma oscillation power in rats. In the present study, hippocampal CA1 local field potentials (LFP) were recorded from bilateral CA1 in urethane-anaesthetized mice that were reared in either an ENR or ISO condition. Similar to previous findings in rats, gamma oscillation power during theta states was higher in the ENR group. Ripple events that occur during non-theta periods in the CA1 stratum pyramidale also had longer intervals in ISO mice. Because astrocytic Ca 2+ elevations play a key role in synaptic plasticity, we next tested whether these changes in LFP are also expressed in inositol trisphosphate receptor type 2 (IP3 R2)-knockout (KO) mice, in which astrocytic Ca 2+ elevations are largely diminished. We found that the gamma power was also higher in IP3 R2-KO-ENR mice compared to IP3 R2-KO-ISO mice, suggesting that the rearing-environment-dependent gamma power alteration does not necessarily require the astrocytic IP3 /Ca 2+ pathway. By contrast, ripple events showed genotype-dependent changes, as well as rearing condition-dependent changes: ISO housing and IP3 R2 deficiency both lead to longer inter-ripple intervals. Moreover, we found that ripple magnitude in the right CA1 tended to be smaller in IP3 R2-KO. Because IP3 R2-KO mice have been reported to have depression phenotypes, our results suggest that ripple events and the mood of animals may be broadly correlated. Key points: Mice reared in an enriched environment are demonstrated to have larger hippocampal gamma oscillations than those reared in isolation, thereby confirming previous observations in rats. To test whether astrocytic Ca 2+ surges are involved in this experience-dependent LFP pattern modulation, we used inositol trisphosphate receptor type 2 (IP3 R2)-knockout (KO) mice, in which IP3 /Ca 2+ signalling in astrocytes is largely diminished. We found that this experience-dependent gamma power alteration persists in the KO mice. Interestingly, hippocampal ripple events, the synchronized events critical for memory consolidation, are reduced in magnitude and frequency by both isolated rearing and IP3 R2 deficiency
Shinkei seikagaku manyuaru( Book )

1 edition published in 1990 in Japanese and held by 1 WorldCat member library worldwide

 
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Handbook of neurochemistry and molecular neurobiology Handbook of Neurochemistry and Molecular Neurobiology Neural Signaling Mechanisms
Covers
Handbook of Neurochemistry and Molecular Neurobiology Neural Signaling Mechanisms
Alternative Names
Katsuhiko Mikoshiba.

Katsuhiko Mikoshiba Japanese physician

Katsuhiko Mikoshiba Japans arts

Katsuhiko Mikoshiba médecin japonais

Mikoshiba, Katsuhiko 1945-

Микосиба, Кацухико

ミコシバ, カツヒコ

ミコシバ, カツヒコ 1945-

御子柴克彦 1945-

Languages
English (41)

Japanese (27)