WorldCat Identities

Sanger, Frederick 1918-2013

Works: 20 works in 42 publications in 1 language and 489 library holdings
Roles: Author, Editor
Classifications: QP514, 574.192
Publication Timeline
Most widely held works by Frederick Sanger
Selected papers of Frederick Sanger : with commentaries by Frederick Sanger( Book )

8 editions published in 1996 in English and held by 85 WorldCat member libraries worldwide

This important volume is mainly concerned with the development of methods for "sequencing"--That is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences
The biochemical approach to life by F. R Jevons( Book )

4 editions published in 1964 in English and held by 11 WorldCat member libraries worldwide

Permafrost : ... internat. conference( Book )

2 editions published between 1983 and 1984 in English and held by 2 WorldCat member libraries worldwide

The role of protein and nucleic acid sequences in living matter( Recording )

2 editions published in 1973 in English and held by 2 WorldCat member libraries worldwide

The determination of sequences( Recording )

1 edition published in 1973 in English and held by 1 WorldCat member library worldwide

The gene code( Visual )

1 edition published in 2011 in English and held by 1 WorldCat member library worldwide

The second in a two-part series in which genetist and science journalist Adam Rutherford looks in depth at DNA. In this part, Rutherford asks how decoding the 'book of life' (the human genome) helps us understand who we are. He explains what DNA is. A biologist, Hugh Young Rienhoff, from America used home-diagnostic kits to ascertain his daughter's unique and unknown genetic condition. Next, Rutherford goes back 50 years to the work of Crick and Watson, the discoverers of the double helix shape. A physicist interested in how the amino acids interacted, George Gamow, contacted Crick and Watson to further this work. Then, in the US, two young scientists, J. Heinrich Matthaei and Marshall Warren Nirenberg discovered a combination of acids which made a single protein; this became the 'Rosetta Stone' of DNA. Rutherford asks how our DNA effects variation in our hereditary such as hair colour. Professor Kay Davies then discusses Muscular Dystrophy which effects boys and leads to poor muscle tone, disability and limited life expectancy. This has led to accurate pre-natal diagnosis. However, being diagnosed with a genetic disease is not easy. Former war correspondent, Charles Sabine, discusses his diagnosis of Huntingdon's Disease which always leads to mental impairment and then death. All these disease are rare; they are known as mono-genic. Rutherford considers height which is poly-genic. The interactions between the genes is commonly known as 'Sanger-sequencing' after the Nobel prize winning researcher, Fred Sanger. Rutherford illustrates this using a pack of playing cards. By 2001, decoding the entire human genome was completed. Dr Ewan Birney talks to Rutherford about his work discovering how many genes we actually have. He provides evidence illustrating how diverse estimates were at the time; there are in fact around 24,000 in humans. Within the human genome it was discovered that 98% of our DNA could be 'junk'. Professor Peter Donnelly, director, of the Wellcome Trust Sanger Centre, describes how we are more similar than different. In a project that studied both sick and well people, seven common disease such as coronary heart disease and diabetes are shown to be genetic in nature. This does not take into account the environment such as exercise and diet. Dr Claire Howarth talks about twins and her studies in various traits such as height. Many traits are highly hereditable, but not in evidence in the mapped genome, known as 'missing hereditability'. Current thought is that some of this data will be in the 'junk' DNA. Professor Mark McCarthy from the University of Oxford uses new technology to look at diabetes sufferers and see what further variants can be discovered. Ewan Birney then talks about the project ENCODE; to form an encyclopaedia of DNA. He describes the choreography of the molecules which form a much more complex relationship. The dark matter of DNA looks to be more important, indeed the shape itself seems signifcant
The gene code( Visual )

1 edition published in 2011 in English and held by 1 WorldCat member library worldwide

A compilation of two consecutive programmes on the subject of DNA presented by the science journalist Adam Rutherford
First human genome sequence press launch( Visual )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

Camera rushes of the Wellcome Trust press launch relating to the sequencing of the first human genome held on the 7th December 1999 in the Henry Wellcome auditorium at Wellcome Collection, Euston Road, London (before renovation). On the podium are Michael Dexter, then director of Wellcome Trust, and Michael Morgan. In the audience are Dr John Sulstan and Fred Sanger. Wellcome Trust answers questions posed by the scientific press
DNA code cracked( Recording )

1 edition published in 2000 in English and held by 1 WorldCat member library worldwide

Interviews with Dr Fred Sanger and Dr James Watson, on the day that the announcement is due to be made that the DNA Code has been cracked. The completion of a rough draft of the human genome
Audience Level
Audience Level
  Kids General Special  
Audience level: 0.47 (from 0.22 for Frederick ... to 0.97 for The role o ...)

Selected papers of Frederick Sanger : with commentaries
Alternative Names
Frederick Sanger britischer Biochemiker und Nobelpreisträger für Chemie

Frederick Sanger Brits biochemicus (1918-2013)

Frederick Sanger chimico britannico

Frederik Sanger

Frederik Senger

Frederiks Sengers

Fridericus Sanger

Sanger, F.

Sanger, Fred 1918-2013

Φρέντερικ Σάνγκερ

Сенгер, Фредерик

Фредерик Сангер

Фредерик Сангър

Фредерік Сенгер

Фрэдэрык Сенгер

Ֆրեդերիկ Սանգեր

פרדריק סנגר

فردريك سانغر

فردریک سنگر

فریڈرک سنگر

فریڈرک سینگر

फ्रेड्रिक सैंगर

ফ্রেডরিক স্যাঙ্গার

பிரடெரிக் சேனர்

ఫ్రెడెరిక్ సాంజెర్

ഫ്രെഡറിക് സാങ്ങർ

생어, 프레데릭 1918-

프레더릭 생어



English (31)