WorldCat Identities

Buxbaum, Joseph D.

Overview
Works: 11 works in 37 publications in 2 languages and 1,192 library holdings
Genres: Academic theses  Conference papers and proceedings 
Roles: Editor, Author, Contributor
Publication Timeline
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Most widely held works by Joseph D Buxbaum
The Neuroscience of Autism Spectrum Disorders by Joseph D Buxbaum( )

12 editions published between 2012 and 2014 in English and Italian and held by 1,011 WorldCat member libraries worldwide

Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available
Neurobiology of mental illness by Eric J Nestler( Book )

11 editions published between 2013 and 2014 in English and held by 144 WorldCat member libraries worldwide

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psyc
Charney & Nestler's neurobiology of mental illness( Book )

3 editions published between 2017 and 2018 in English and held by 26 WorldCat member libraries worldwide

In the years following publication of the DSM-5, the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and this edition extends beyond its reference function to acknowledge and examine the controversies and thoughts on the future of psychiatric diagnosis.In this wider context, this book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior
The emerging neuroscience of autism spectrum disorders by Society for Neuroscience( Book )

3 editions published in 2011 in English and held by 3 WorldCat member libraries worldwide

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease by Valentina Escott-Price( )

2 editions published in 2014 in English and held by 2 WorldCat member libraries worldwide

Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls. Principal Findings: In addition to earlier reported genes, we detected genome-wide significant loci on chromosomes 8 (TP53INP1, p = 1.4x10(-6)) and 14 (IGHV1-67 p = 7.9x10(-8)) which indexed novel susceptibility loci. Significance: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease
The Autism Simplex Collection : an international, expertly phenotyped autism sample for genetic and phenotypic analyses by Joseph D Buxbaum( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Calsenilin - a neuronal calcium sensor by Christina Lilliehook( )

1 edition published in 2002 in English and held by 1 WorldCat member library worldwide

In mouse, calsenilin is strongly expressed in granule cells of dentate gyrus in hippocampus but is absent or present at low levels in CA pyramidal cells. Likewise, in cerebellum calsenilin is strongly and selectively expressed in the granule cell layer, and in cortex calsenilin expression appears to be restricted to layer 6, piriform and entorhinal cortices. Long-term potentiation is enhanced specifically in dentate gyrus of calsenilin null animals, and Abeta42 peptide levels are significantly reduced in cerebellum of calsenilin knockouts. In vivo, calsenilin may regulate both Kv4 channels and presenilins
Neuropathology of the posteroinferior occipitotemporal gyrus in children with autism by Neha Uppal( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Charney et Nestler's neurobiology of mental illness( Book )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

The neuroscience of autism spectrum disorders( Book )

1 edition published in 2013 in English and held by 1 WorldCat member library worldwide

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder by Jillian P Casey( )

1 edition published in 2013 in English and held by 1 WorldCat member library worldwide

 
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Alternative Names
Joseph Buxbaum American neuroscientist

Joseph Buxbaum americký neurovědec

Joseph Buxbaum Amerikaans neurowetenschapper

Languages