WorldCat Identities

Roman Alemany, Oscar

Works: 40 works in 44 publications in 1 language and 70 library holdings
Roles: Author
Publication Timeline
Most widely held works by Oscar Roman Alemany
Ideología y política en el siglo XXI by Oscar Román A.( Book )

4 editions published in 2002 in Spanish and held by 25 WorldCat member libraries worldwide

Seguridad y eficacia de celiprolol en hipertensos con enfermedad pulmonar obstructiva cronica by Marco Chahuan Y.( )

1 edition published in 2000 in Spanish and held by 2 WorldCat member libraries worldwide

Background: Third generation beta blockers have an intrinsic simpatico-mimetic activity and are cardioselective. Therefore, they should not have adverse bronchial effects and could even have a slight bronchodilator activity. Aim: To test the efficacy and safety of celiprolol in hypertensive patients with chronic obstructive lung disease. Patients and methods: Uncomplicated hypertensive patients with chronic obstructive lung disease received celiprolol during 12 weeks. They were subjected to monthly clinical assessment and ventilatory function was measured on the basal period and at the end of the trial. Results: During the study period, blood pressure fell significantly from 179n6/112n8 to 161n4,7/98n1.6 mmHg. No changes were observed in forced expiratory volume in 1 s or in forced expiratory flow between 25 and 75 percent of the vital capacity. No subjective changes in respiratory function were reported during the trial. Conclusions: No changes in ventilatory function were observed in these patients with chronic obstructive lung disease, treated with celiprolol during 12 weeks (AU)
Enfermedades del corazón y grandes vasos by Francisco Rojas Villegas( Book )

2 editions published in 1986 in Spanish and held by 2 WorldCat member libraries worldwide

Recomendaciones sobre el uso de la monitorizacion ambulatoria de presion arterial: documento de consenso de la Sociedad Chilena de Hipertension by Hernan Prat Martorell( )

1 edition published in 1999 in Spanish and held by 2 WorldCat member libraries worldwide

Continuous ambulatory blood pressure monitoring is a diagnostic technique devised as a consequence of the great variations in blood pressure measurements. It allows multiple daily measurements, nocturnal monitoring, avoids the stress of blood pressure measurements, gives a picture of pressure behavior during 24 hours and reduces observer related errors. The equipment used must be accurate and validated using international protocols. Accepted indications for continuous ambulatory blood pressure monitoring are white coat hypertension, episodic hypertension, resistance to medications and assessment of symptoms or autonomic dysfunction. Other indications with less clear cut usefulness, are high risk cardiac, renal or pregnant patients and an accurate blood pressure control. We describe equipment calibration, elements that must be considered in the reports, result interpretation and conclusions. Normal blood pressure ranges for children and pregnant women are also reported (AU)
Contaminacion atmosferica y dano cardiovascular by Oscar Román A.( )

1 edition published in 2004 in Spanish and held by 2 WorldCat member libraries worldwide

The damaging effect of atmospheric pollution with particulate matter and toxic gases on the respiratory system and its effect in the incidence and severity of respiratory diseases, is well known. A similar effect on the cardiovascular system is currently under investigation. Epidemiological studies have demonstrated that the inhalation of particulate matter can increase cardiovascular disease incidence and mortality, specially ischemic heart disease. The damage would be mediated by alterations in the autonomic nervous system, inflammation, infections and free radicals. In human studies, environmental pollution is associated with alterations in cardiac frequency variability and blood pressure and with changes in ventricular repolarization. Experimentally, an enhancement of ischemia, due to coronary obstruction, has been demonstrated. The study of the toxic effects of environmental pollution over the cardiovascualr system, is an open field, specially in Chile, were the big cities have serious contamination problems (Rev Med Chile 2004; 132: 761-7). (AU)
Influencia de factores de riesgo y terapia farmacologica en la mortalidad de hipertensos esenciales by Oscar Román A.( )

1 edition published in 1998 in Spanish and held by 2 WorldCat member libraries worldwide

Background: The V JNC consensus stated that although new antihypertensive agents, such as angiotensin converting enzyme inhibitors and calcium channel blockers, are considered safer drugs, there is no firm evidence from large controlled trials that these drugs are associated with a lower cardiovascular mortality. Aim: To study the association between cardiovascular risk factors, blood pressure levels, pharmacological treatment and mortality in a group of hypertensive patients followed at an hypertension outpatient clinic. Patients and methods: Patients with essential hypertension were treated with different antihypertensive medications, according to physicians criteria, and controlled until death or loss from follow up. Causes of death were obtained from hospital records and death certificates. Survival was analyzed using life tables, comparisons between groups of patients were done using chi square or a Cox's proportional hazards model. Results: Three hundred thirty nine hypertensive patients aged 33 to 80 years old were followed for a mean period of 9.8 n 4.9 years. Eighty six were treated with beta blockers, 64 with diuretics, 133 with calcium antagonists and 56 with ACE inhibitors. Blood pressure dropped similarly with all medications. During follow up, 79 patients died. Life table analysis showed that patients with a history of angina, diabetes or myocardial infarction had higher mortality rates. Similarly, patients treated with beta blockers and diuretics had higher mortality than patients treated with calcium antagonists or angiotensin converting enzyme inhibitors. The proportional hazards model showed that the effect of treatment modality persisted after correction for the other risk factors for mortality. Conclusions: In this series of hypertensive patients, those treated with beta blockers or diuretics had higher mortality rates than those receiving calcium channel antagonists or angiotensin converting enzyme inhibitors (AU)
Optimizacion de la reduccion de la presion arterial en hipertensos esenciales by Oscar Román A.( )

1 edition published in 2002 in Spanish and held by 2 WorldCat member libraries worldwide

Background: A blood pressure below or equal to 140/90 mmHg, the aim of antihypertensive treatment, is rarely achieved. Only 16 percent of patients controlled by our group reach this goal. Aim: To analyze the causes of suboptimal treatment and to assess the effects of an optimization of antihypertensive therapy. Patients and methods: A random sample of 160 patients was analyzed and followed during one year. Results: Sixty six patients (41 percent) had a normal blood pressure, maintained during the first three months of follow up. The main causes of suboptimal reduction of blood pressure in the remaining 94 patients were an incorrect prescription or dosage of medications in 37.5 percent, lack of compliance in 34 percent, insufficient delivery of medications by the health service in 24 percent and secondary effects of drugs in 5 percent. When these factors were corrected, blood pressure normalized in 41 of them. In other 37, a reduction of 5 mmHg or more in blood pressure, was obtained. The most frequent changes introduced were modifications in dosage and addition of a new medication. Therefore, in 90 percent of these patients, blood pressure was reduced or normalized. Conclusions: A correct identification of the cause of antihypertensive treatment failure is imperative. The correction of this cause leads to a further reduction in blood pressure in 90 percent of those subjects with suboptimal treatment (AU)
Hemodinamia arterial periferica no invasiva en la hipertension arterial by Oscar Román A.( )

1 edition published in 1990 in Spanish and held by 1 WorldCat member library worldwide

La introduccion de la ecocardiografia bidimensional y el Doppler ha permitido su aplicacion simultanea al estudio de la hemodinamia arterial periferica, por lo que se ha disenado un estudio en arteria braquial en hipertensos no tratados para establecer sus caracteristicas hemodinamicas en comparacion a un grupo normal de control. En 76 hipertensos, edad promedio 60 n 12 anos; PA promedio = 176/105 mmHg y en 57 normales, PA promedio 118/73 mmHg, con distribucion por edad y sexo comparables, se midio diametro y velocidad de flujo arteriales y se calcularon volumen sanguineo local, resistencia vascular y distensibilidad arterial. Se comprobo que para similar sexo y edad, los hipertensos tienen significativamente mayor diametro arterial y menor velocidad de flujo que los normales, y que los hipertensos jovenes presentan precozmente aumento importante del diametro, con aumento de la resistencia vascular y disminucion de la distensibilidad. A mayor PA sistolica correspondio mayor diametro arterial (r = 0,50) tanto en normales como hipertensos. La velocidad de flujo, que depende del tono de las arterias, tuvo en cambio "r" limite significativo con la PA diastolica (r = 0,44) para el total de normales e hipertensos. Se concluye que esta tecnica aporta datos hemodinamicos significativos para el diagnostico precoz del hipertenso al revelar un aumento importante del diametro arterial y de la resistencia vascular y una disminucion de la distensibilidad arterial (AU)
La insuficiencia cardiaca como complicacion de la hipertension arterial: caracteristicas epidemiologicas, clinicas y ecocardiograficas by Oscar Román A.( )

1 edition published in 1993 in Spanish and held by 1 WorldCat member library worldwide

El tratamiento farmacologico de la hipertension arterial primaria ha reducido la incidencia de la IC, que era la complicacion mas frecuente en su historia natural. Sin embargo, como aun persiste, se estudiaron su incidencia, factores pronosticos y caracteres clinico y ecocardiografico en una cohorte de 837 hipertensos seguidos 16 anos con terapia farmacologica a base de diureticos (solos 23%, asociados 47%), betabloqueadores (solos 32%, asociados 47%) y vasodilatadores, antagonistas del Ca++ e inhibidores de la ECA (solos 5% y asociados 9%). Treinta y ocho pacientes desarrollaron IC en el seguimiento (tasas 9,6% a 7 anos, 8,2% a 12 anos y 6,1% a 16 anos, diferencias no significativas), 15 fallecieron (tasa 1,9% a 16 anos). Los factores pronosticos significativos (segun modelo de riesgos proporcionales de Cox) fueron grado de avance lesional (OMS) al ingreso, PA diastolica promedio intraterapia y numero de antecedentes morbidos preexistentes, de los cuales la diabetes y la enfermedad coronaria fueron los mas relevantes y significativos (en 7 de 10 coronarios, el compromiso coronario fue directamente responsable de la IC). La HTA aparecio como causa unica de IC en el 58%, asociada a enfermedad coronaria en el 26,5%, a insuficiencia renal en el 13,3% y a aneurisma disecante aortico 2,5%. De los 16 pacientes con evolucion ecocardiografica anual (7anos), la mitad desarrollo dilatacion del VI con disfuncion sistolica y la otra mitad mantuvo hipertrofia concentrica con camara normal y disfuncion diastolica(AU)
Tratamiento de la hipertension leve con captopril y captopril e hidroclorotiazida: impacto en cifras tensionales y calidad de vida by Edgardo Escobar Cerda( )

1 edition published in 1993 in Spanish and held by 1 WorldCat member library worldwide

Un analisis de la situacion actual de las especialidades medicas en Chile by Oscar Román A.( )

1 edition published in 2002 in Spanish and held by 1 WorldCat member library worldwide

During the fifties and sixties, physicians were mostly prepared as general practitioners. However, the progress in scientific knowledge and the introduction of complex technologies required the training of specialists. A number of sub specialties have been progressively added to the four basic specialties, namely Internal Medicine, Pediatrics, Obstetrics and Gynecology and General Surgery. The Post Graduate Schools of the traditional universities devised courses and training periods to teach these sub specialties. The Association of Medicine Schools has been in charge of the accreditation of the new training centers. Since the training of new specialists required the collaboration of hospitals of the public National Health Service, there is a special commission that coordinates the relationships between teaching requirements and medical attention in these hospitals. There is still a controversy on the exact proportion of general practitioners and specialists that the country needs, the role of Family Practice and the role of prevention and health promotion (AU)
Terapia combinada de un antagonista de Ca++ y un inhibidor de la enzima convertidora de la angiotensina en hipertension arterial esencial by Oscar Román A.( )

1 edition published in 1997 in Spanish and held by 1 WorldCat member library worldwide

La terapia combinada de un antagonista de Ca++ y un inhibidor de la enzima convertidora de la angiotensina, ademas de mejorar la tolerancia (menores dosis), permitiria mejor control de la PA por la accion amortiguadora que tienen los IECA sobre la estimulacion del sistema RAA y del sistema simpatico que ejercen los antagonistas del Ca++. Para estudiar la respuesta clinica a esta asociacion, 84 hipertensos esenciales moderados (PAS entre 161-200 mmHg y PAD entre 114-120 mmHg) en etapas I-II OMS, fueron tratados con nifedipino 10 mg x 3 v. o enalapril 10 mg x 2 v. durante 3 ms. Cuarenta pac no lograron normotension (<140/90 mmHg), de los cuales 19 recibian enalaptil y 21, nifedipino, por lo que se les asocio el otro farmaco a dosis similar. Ambos grupos resultaron comparables en edad, sexo y niveles de la PA con monoterapia. La terapia combinada produjo desde el primer mes una nueva y significativa reduccion de PA. Individualmente, 17 pac (42,5 por ciento) alcanzaron normotension, 19 pac redujeron sus niveles de PAD entre 91 y 100 mmHg y solo en 4 pac (10 por ciento) fracaso la combinacion. Los efectos adversos fueron los clasicos para estas drogas: 33 por ciento con monoterapia y 20 por ciento con terapia combinada. Se concluye que en hipertension esencial, de moderada a severa, la asociacion de nifedipino y enalapril, a dosis moderadas, permite un control adecuado de la PA con menos efectos adversos (AU)
Farmacologia de los beta-bloqueadores adrenergicos by Oscar Román A.( )

1 edition published in 1991 in Spanish and held by 1 WorldCat member library worldwide

Equidad, un fundamento de la dimension social de la salud by Oscar Román A.( )

1 edition published in 1997 in Spanish and held by 1 WorldCat member library worldwide

Fisiologia del metabolismo del magnesio by Hugo Gonzalez( )

1 edition published in 1992 in Spanish and held by 1 WorldCat member library worldwide

Se revisan los principales aspectos del metabolismo del Mg. Se senala que el aporte dietario oscila alrededor de los 300 mg diarios y que la absorcion ocurre mayoritariamente en el intestino delgado terminal y que solo alcanza entre el 30 y 50%. La mayor parte de lo ingerido se excreta por las heces (200 mg). La magnesemia fluctua entre 1,7 y 2,3 mg% y no refleja fielmente lo que ocurre a nivel intracelular que es lo interesante ya que el Mg++ es el ion intracelular mas importante despues del K+. El adulto normal promedio tiene alrededor de 24 gramos de Mg de los cuales el 60% se encuentra en los huesos, el 35% en los musculos esqueleticos y miocardio y solo el 1% en la sangre. Se enfatiza el rol del riñón en el metabolismo del Mg. A nivel glomerular ultrafiltran diariamente alrededor de 2.500 mg de Mg de los cuales solo se excretan unos 100 mg por la orina. De los 2.400 mg no excretados, el 35% se reabsorbe en los tubulos proximales y el 65% en la rama ascendente de asa de Henle. Se mencionan las principales funciones del Mg en el organismo, destacando que, en combinacion con el ATP participa en la mayoria de las reacciones metabolicas, en la regulacion de la actividad de los ribosomas; en la generacion y transmision del impulso nervioso, etc. (AU)
Morbimortalidad de la hipertensión arterial esencial tratada en un seguimiento de 26 años by Oscar Román A.( )

1 edition published in 2002 in Spanish and held by 1 WorldCat member library worldwide

Background: Treatment has a definitive impact on mortality in hypertension. The magnitude of blood pressure reduction, the type of drug used and the associated risk factors may modulate the effect of treatment on mortality. Aim: To report the effects of treatment of essential hypertension, in a cohort followed for up to 26 years. Patients and methods: A cohort of 1,172 essential hypertensive patients followed up to 26 years. Patients were treated with different antihypertensive drugs, alone or in combination (diuretics, beta blockers, calcium channel blockers and angiotensin converting enzyme inhibitors) according to international rules and consensus. Subjects were followed until death or loss from follow-up. Blood pressure reduction was aimed to obtain figures near 140/ 90 mm Hg. Causes of death and complications were obtained from hospital records, phone and death certificates. Survival was studied using life tables (Kaplan Meier method and intention to treat analysis) and Cox proportional hazard analysis. Results: Initial blood pressure dropped significantly from 181/109 to 154/92 mm Hg, p <0.001. Mean follow-up time was 10.6"6.1 years. There were 143 cardiovascular deaths, 142 acute myocardial infarctions, 101 strokes, 83 subjects had cardiac failure and 49 had renal failure. The observed rates were 0.92% per year for cardiovascular mortality, 1.36% per year for coronary heart disease, 0.94% per year for stroke. Conclusions: Our mortality rate is lower than that found in classical randomized studies but similar or slightly higher than the more recent ones. Morbidity rates were also very similar. Except for mortality rate, frequency of complications did not change in comparison to our previous report after 15 year of follow up. Aging did not seem to negatively influence mortality rates in adequately treated hypertensive patients (Rev Méd Chile 2002; 130: 379-38)
Insulinemia en ayunas como marcador simple de resistencia a la insulina en hipertensos by Oscar Román A.( )

1 edition published in 1995 in Spanish and held by 1 WorldCat member library worldwide

Insulin resistance is associated to hypertension, obesity and diabetes and may be an independent cardiovascular risk factor. The exact assessment of insulin resistance requires complex metabolic studies. However, there is a good correlation between this parameter and fasting serum insulin levels. The aim of this work was to study fasting serum insulin levels by ratio immuno analysis in 43 hypertensive patients aged 56 n 5.5 years old (27 male, 17 obese and 8 diabetics) and 20 normotensive controls aged 50 n 4.8 years old (13 male). Insulin levels were 3.8 UI/L in controls, 12.1 UI/L in normal weight, 15.5 UI/L in obese and 18.3 UI/L in diabetic hypertensives (ANOVA p<0.001). These levels were above two standard deviation of control values in 50 percent of normal weigth, 66 percent of obese and 62 percent diabetic hypertensives. It is conclude that normal weigth, obese and diabetic hypertensive subjects have high fasting insulin levels (AU)
Estudio colaborativo chileno-argentino, para evaluar nifedipina OROS en hipertensos esenciales by Gloria Valdes( )

1 edition published in 1997 in Spanish and held by 1 WorldCat member library worldwide

Ocho centros chilenos y 5 argentinos evaluaron eficacia, tolerabilidad y seguridad de Nifedipina Oros en 355 hipertensos esenciales durante 8 semanas de tratamiento, previo placebo. 67 por ciento pacientes respondieron a 30, y 33 por ciento a 60 mg/dia. El descenso de presion arterial fue 23/15 n 0.6/0.3 (ES) mmHg (p <0,0001). Las variaciones de presion fueron similares en decubito y de pie, sin causar diferencias en frecuencia cardiaca en ambas posiciones. La relacion trough: peak (28:6-8 h) vario entre 0,91-0,95 con dosis inicial o de mantencion. Ochenta y cuatro por ciento de hipertensos leves y 93 por ciento de moderados respondieron con decrementos de 10 o mas mmHg; 59 por ciento alcanzaron normotension. No se observaron respuestas significativamente diferentes segun edad y terciles de Na urinario nocturno al ingreso. No hubo modificacion de parametros de laboratorio. 29 por ciento de los pacientes presentaron efectos colaterales durante tratamiento activo; en 65 por ciento unicos, en 63 por ciento leves y bien tolerados. Los mas frecuentes al final del tratamiento fueron cefaleas (4,7 por ciento) y edema (2,6 por ciento). Once pacientes fueron retirados por efectos que interferian la vida habitual y 4 abandonaron control. Concluimos que Nifedipina GITS posee alta eficacia, similar para distintos grupos etareos e ingesta de sodio, un efecto mantenido a lo largo de las 24 horas y efectos colaterales mayoritariamente leves y bien tolerados (AU)
Avances en el tratamiento de la hipertension arterial by Oscar Román A.( )

1 edition published in 1998 in Spanish and held by 1 WorldCat member library worldwide

El tratamiento de la hipertension arterial tiene por objetivos el reducir las cifras tensionales y disminuir la morbi-mortalidad de la afeccion. En los ultimos anos se ha agregado ademas el control de los factores de riesgo involucrados en los estilos de vida. La clasificacion actualmente aceptada de las cifras tensionales arterial reconoce como valores optimos 180>110 mmHg). Se destaca la importancia de las medidas terapeuticas no farmacologicas orientadas a modificar el estilo de vida (reduccion de peso y del sedentarismo; disminucion de ingesta de alcohol y sodio). Se enfatizan los avances realizados en el campo de los tratamientos farmacologicos, los que deben iniciarse en forma progresiva de acuerdo a la respuesta obtenida y a los efectos colaterales observados, siendo el ideal la administracion de monoterapia en monodosis (una sola dosis diaria). Los farmacos actualmente disponibles se analizan por familias: diureticos; betabloqueadores; bloqueadores adrenegicos alfa 1; antagonistas del calcio; inhibidores de la enzima de conversion de la angiotensina; bloqueadores de los receptores AT-1 de la angiotensina. Finalmente se presenta una estrategia terapeutica que se basa en los factores de riesgo y la severidad de la hipertension (AU)
La red asistencial de salud y el papel de los jefes de servicios clinicos en su gestion: un punto de vista desde el Hospital Clinico San Borja Arriaran by Oscar Román A.( )

1 edition published in 1997 in Spanish and held by 1 WorldCat member library worldwide

Se analizan los niveles de atencion en las areas de Salud de Chile, y en especial los problemas del nivel primario. Entre estos problemas se destacan: los" de naturaleza medica profesional; la administracion municipal, que ha desmembrado la red de atencion; y la insuficiencia de acciones de promocion basadas en el modelo biopsicosocial de la persona. Se examina la realidad de las relaciones entre el nivel primario y el secundario; el rol de los Centros de Diagnostico y Tratamiento (CDT) y el de atencion cerrada. Se concluye, sobre la base de la experiencia de los autores, que los jefes de servicios clinicos, o el profesor universitario, o ambos en el marco de un consejo tecnico de la red deben planificar, supervisar y evaluar todos los niveles de la red local, incluyendo los consultorios o centros de salud y los CDT, con el objeto de entregar una atencion medica integrada, continua y de calidad (AU)
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Ideología y política en el siglo XXI
Alternative Names
Román Alemany, Oscar

Román, Oscar

Román, Oscar (Román Alemany)

Spanish (24)