WorldCat Identities

Richardson, Jane S.

Overview
Works: 12 works in 17 publications in 1 language and 18 library holdings
Roles: Author
Publication Timeline
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Most widely held works about Jane S Richardson
 
Most widely held works by Jane S Richardson
Kinemage supplement to Introduction to protein structure, second edition by Jane S Richardson( )

2 editions published in 1999 in English and held by 4 WorldCat member libraries worldwide

Molecular structures in biology by R Diamond( Book )

2 editions published between 1991 and 1993 in English and held by 3 WorldCat member libraries worldwide

The Kinemage Supplement to introduction ot protein structure by Jane S Richardson( )

3 editions published in 1999 in English and held by 3 WorldCat member libraries worldwide

Kinemage supplement : to an introduction to protein structure( )

1 edition published in 1999 in English and held by 2 WorldCat member libraries worldwide

Kinemages are interactive, three-dimensional molecular illustrations viewed using the MAGE program. The kinemages of this supplement demonstrate the fully three-dimensional nature of the proteins described and illustrated in Introduction to Protein Structure, second ed
Model validation: local diagnosis, correction and when to quit( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Abstract : An overview is provided of current crystallographic model validation of proteins and RNA, both foundations and criteria, at all resolution ranges, together with advice on how to correct specific types of problems and when you should not try so hard that you are overfitting. Abstract : Traditionally, validation was considered to be a final gatekeeping function, but refinement is smoother and results are better if model validation actively guides corrections throughout structure solution. This shifts emphasis from global to local measures: primarily geometry, conformations and sterics. A fit into the wrong local minimum conformation usually produces outliers in multiple measures. Moving to the right local minimum should be prioritized, rather than small shifts across arbitrary borderlines. Steric criteria work best with all explicit H atoms. `Backrub' motions should be used for side chains and `P‐perp' diagnostics to correct ribose puckers. A `water' may actually be an ion, a relic of misfitting or an unmodeled alternate. Beware of wishful thinking in modeling ligands. At high resolution, internally consistent alternate conformations should be modeled and geometry in poor density should not be downweighted. At low resolution, CaBLAM should be used to diagnose protein secondary structure and ERRASER to correct RNA backbone. All atoms should not be forced inside density, beware of sequence misalignment, and very rare conformations such as cis ‐non‐Pro peptides should be avoided. Automation continues to improve, but the crystallographer still must look at each outlier, in the context of density, and correct most of them. For the valid few with unambiguous density and something that is holding them in place, a functional reason should be sought. The expectation is a few outliers, not zero
The kinemage supplement to Introduction to protein structure by Jane S Richardson( )

in English and held by 1 WorldCat member library worldwide

Broad Analysis of Vicinal Disulfides: Occurrences, Conformations with Cis or with Trans Peptides, and Functional Roles Including Sugar Binding( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract: Vicinal disulfides between sequence-adjacent cysteine residues are very rare and rather startling structural features which play a variety of functional roles. Typically discussed as an isolated curiosity, they have never received a general treatment covering both cis and trans forms. Enabled by the growing database of high-resolution structures, required deposition of diffraction data, and improved methods for discriminating reliable from dubious cases, we identify and describe distinct protein families with reliably genuine examples of cis or trans vicinal disulfides and discuss their conformations, conservation, and functions. No cis-trans interconversions and only one case of catalytic redox function are seen. Some vicinal disulfides are essential to large, functionally coupled motions, whereas most form the centers of tightly packed internal regions. Their most widespread biological role is providing a rigid hydrophobic contact surface under the undecorated side of a sugar or multiring ligand, contributing an important aspect of binding specificity. Graphical Abstract: Highlights: The vicinal SS bond plays highly varied functional roles but lacks an overall study. Despite earlier claims, protein vicinal SS can use either cis - or trans -peptide forms. Four reliably valid conformations are seen, which do not interconvert dynamically. Functions include rigidity, mobility, or binding specificity, a few with redox change. Broad, validated analysis clarifies conformations, changes, and a new sugar-binding role
The "de novo" design of protein structures by Jane S Richardson( Book )

1 edition published in 1989 in English and held by 1 WorldCat member library worldwide

VIEW-An exploratory molecular visualization system with user definable interaction sequences by Lawrence D Bergman( )

1 edition published in 1993 in English and held by 1 WorldCat member library worldwide

Exploring molecular structure( )

2 editions published in 1994 and held by 0 WorldCat member libraries worldwide

An interactive set of exercises designed to explore major topics in biochemistry. Exercises were constructed using Kinemages, computer graphics developed by Jane and David Richardson for viewing and manipulating macromolecular structures in three dimensions
The kinemage supplement to introduction to protein structure by Jane S Richardson( Book )

in English and held by 0 WorldCat member libraries worldwide

 
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Kinemage supplement to Introduction to protein structure, second edition The Kinemage Supplement to introduction ot protein structure Kinemage supplement : to an introduction to protein structure
Covers
The Kinemage Supplement to introduction ot protein structureKinemage supplement : to an introduction to protein structure
Alternative Names
Jane Richardson

Jane Richardson Amerikaans biofysica

Jane Richardson Biochemikerin

Jane S. Richardson

Richardson, Jane 1941-

Richardson, Jane Shelby 1941-

ג'ון ס. ריצ'רדסון

جان اس. ریچاردسون

Languages
English (15)