WorldCat Identities

Honjo, T. (Tasuku) 1942-

Overview
Works: 42 works in 136 publications in 2 languages and 3,984 library holdings
Roles: Editor, Author, Other
Classifications: QR1, 616.079
Publication Timeline
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Most widely held works by T Honjo
Immunoglobulin genes by T Honjo( )

24 editions published between 1988 and 2014 in English and Undetermined and held by 1,688 WorldCat member libraries worldwide

Immunoglobin Genes is the first comprehensive book on the structure, function, and expression of the genes encoding antibodies in normal and neoplastic cells
Molecular biology of B cells by Tasuku Honjō( )

6 editions published between 2004 and 2015 in English and held by 607 WorldCat member libraries worldwide

A key comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotypes for those who are specialised in immunology as well as in other biomedical disciplines. The molecular basis of many diseases due to B cell abnormality are discussed and the new technology that indicates medical applications for antibodies is highlighted
Gut-associated lymphoid tissues by T Honjo( )

16 editions published in 2006 in English and held by 568 WorldCat member libraries worldwide

The intestine is colonized by an impressive community of commensals, that has profound effects on the immune funtions. The relationship between gut microbiota and the immune system is one of reciprocity: commensals have important contribution in nutrient processing and education of the immune system and conversely, the immune system, particularly gut-associated lymphoid tissues plays a key role in shaping the repertoire of gut microbiota
Negative co-receptors and ligands by Rafi Ahmed( )

11 editions published between 2011 and 2013 in English and held by 483 WorldCat member libraries worldwide

Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules. Fc Receptor-Like molecules (FCRL) that have garnered increasing interest due to their differential patterns of lymphocyte expression and potential involvement in the pathogenesis of autoimmune disorders, immunodeficiency and lymphoid malignancies in humans. Programmed cell death-1 (PD-1) delivers negative signals upon interaction with its two ligands, PD-L1 or PD-L2. The biological significance of PD-1 and its ligand suggest the therapeutic potential of manipulation of PD-1 pathway against various human diseases. TIM-3 acts as a negative regulator of Th1/Tc1 cell function by triggering cell death upon interaction with its ligand, galectin-9. This negative regulatory function of TIM-3 has now been expanded to include its involvement in establishing and/or maintaining a state of T cell dysfunction or 'exhaustion' observed in chronic viral diseases. The Ly49 receptors, which are expressed in a stochastic manner on subsets of murine Natural Killer (NK) cells, T cells, and other cells, are encoded by the Klra gene family and include receptors with either inhibitory or activating function. Most of the inhibitory Ly49 receptors recognize polymorphic epitopes on major histocompatibility complex (MHC) class I proteins as ligands. Fc-receptors for IgG (Fc{uF067}Rs) are widely expressed on innate immune effector cells in mediating the protective function of IgG. This book discusses how the interaction of these different ligands to classical and novel Fc{uF067}-receptors influences the immune response and which strategies microorganisms have developed to prevent them. The host derived cytokine IL-10 is a key player in the establishment and perpetuation of viral persistence.¡ This book covers the role of IL-10 in viral persistence and explores the exciting prospect of therapeutically blocking IL-10 to increase antiviral immunity and vaccine efficacy. TGF-ß inhibits the proliferation of T cells as well as cytokine production via Foxp3-dependent and independent mechanisms. Recent studies suggest that Smad2 as well as Smad3 play essential roles in Foxp3 induction and cytokine suppression, whereas Th17 differentiation is promoted via the Smad-independent pathway. Mutual suppression of signaling between TGF-ß and inflammatory cytokines has been shown to be necessary for the balance of immunity and tolerance
Evolution of life : fossils, molecules, and culture by Shōzō Ōsawa( Book )

8 editions published in 1991 in English and held by 300 WorldCat member libraries worldwide

Nearly thirty million species of organisms are believed to now live on Earth. In addition to accumulating evidence from classical biology, paleontology and earth science, the recent progress of molecular biology has provided new insights into understanding how present-day organisms have evolved with such tremendous diversity. Molecular biological studies show us that all living forms, including E. coli and human beings, derive from a single ancestor that emerged some 4 billion years ago on Earth. This volume aims to discuss the motifs of organismic evolution from the viewpoints of biogeo-interactions and diversification of the genetic systems. Based on these fundamental understandings, the last section of this volume is devoted to human evolution that includes phylogeny of man as well as evolution of human culture. Such comprehensive discussion will give us a synthesized view of the evolution of life, that is undoubtedly one of the most important problems not only for science but also for human culture in general
Aid for immunoglobulin diversity by Frederick W Alt( )

6 editions published in 2007 in English and held by 199 WorldCat member libraries worldwide

Written by one of the leading scientists of our time, The Biology of Human Longevity - Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the
Viruses and nanotechnology by Max D Cooper( )

4 editions published between 2008 and 2009 in English and held by 45 WorldCat member libraries worldwide

Viral nanoparticles (VNPs) serve as excellent nanobuilding blocks for materials design and fabrication. The main advantages are their nanometer-range size, the propensity to self-assemble into monodisperse nanoparticles of discrete shape and size, the high degree of symmetry and polyvalency, and the relative ease of producing large quantities
Malaria : drugs, disease, and post-genomic biology by Richard W Compans( )

7 editions published in 2005 in English and held by 17 WorldCat member libraries worldwide

This volume brings some of the worlds best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two. The opening chapters discuss antimalarials and resistance to them in Africa and Asia. Then there are reviews of the different clinical manifestations of malaria, ranging from uncomplicated infections to severe disease and its complications. This section is followed by detailed reviews of what the new 'omics' offer to investigators of Plasmodium biology and is completed by descriptions of advances in understanding the biology of Plasmodium in the mosquito. If this volume attracts new students and provokes existing investigators to explore new directions, then it will have achieved much of what it has set out to do
Immunobiology of natural killer cell receptors by Richard W Compans( )

4 editions published in 2006 in English and held by 14 WorldCat member libraries worldwide

Natural Killer (NK) cells are large granular lymphocytes of the innate immune system and are involved in direct innate immune reactions against viruses, bacteria, and other triggers of pathology. This book focuses on the nature of recognition events by NK cells and address how these events are integrated to trigger these effector functions
Advances in immunology by Frederick W Alt( Book )

4 editions published between 2006 and 2008 in English and held by 8 WorldCat member libraries worldwide

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research
Koredake wa shitte okitai idenshi igaku no kiso chishiki( Book )

3 editions published in 2003 in Japanese and held by 6 WorldCat member libraries worldwide

Men'eki to ketsueki no kagaku( Book )

2 editions published in 1999 in Japanese and held by 5 WorldCat member libraries worldwide

Inochi towa nanika : Kōfuku genomu yamai by T Honjo( Book )

2 editions published in 2009 in Japanese and held by 5 WorldCat member libraries worldwide

Genomu ga kataru seimeizo : Gendaijin no tame no saishin seimei kagaku nyumon by T Honjo( Book )

2 editions published in 2013 in Japanese and held by 5 WorldCat member libraries worldwide

Idenshi ga kataru seimeizō( Book )

3 editions published in 1986 in Japanese and held by 4 WorldCat member libraries worldwide

Seimeitai no mamorikata( Book )

2 editions published in 1991 in Japanese and held by 3 WorldCat member libraries worldwide

CD4+CD25+ regulatory T cells : origin, function, and therapeutic potential by Richard W Compans( )

4 editions published in 2005 in English and held by 3 WorldCat member libraries worldwide

The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body's own constituents thus preserving its integrity. Multiple mechanisms act in concert to ensure self-tolerance. Additional tolerance mechanisms, collectively referred to as dominant tolerance is by now firmly established. It will offer new conceptual insights and hopefully new tools for the sucessful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival
Men'ekikei ninshiki bunka zōshoku( Book )

2 editions published in 1989 in Japanese and held by 3 WorldCat member libraries worldwide

Seimei no mirai o kataru( Book )

2 editions published in 2003 in Japanese and held by 3 WorldCat member libraries worldwide

Zōshoku bunka inshi to sono juyōtai( Book )

2 editions published in 1991 in Japanese and held by 2 WorldCat member libraries worldwide

 
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Audience level: 0.32 (from 0.09 for Immunoglob ... to 0.94 for Seimei no ...)

WorldCat IdentitiesRelated Identities
Immunoglobulin genes
Covers
Molecular biology of B cellsGut-associated lymphoid tissuesNegative co-receptors and ligandsAid for immunoglobulin diversityMalaria : drugs, disease, and post-genomic biologyImmunobiology of natural killer cell receptorsCD4+CD25+ regulatory T cells : origin, function, and therapeutic potential
Alternative Names
Honjō, T.

Honjo, T. 1942-

Honjo T. (Tasuku)

Honjo, T. (Tasuku), 1942-

Honjō, Tasuku

Honjo, Tasuku 1942-

Honzyō, T. (Tasuku)

Tasuko Honjo

Tasuku Hondžo japonský imunolog

Tasuku Honjo

Tasuku Honjo dokter asal Jepang

Tasuku Honjo immunologiste japonais

Tasuku Honjo immunologo giapponese

Tasuku Honjo investigador japonés

Tasuku Honjo Japanese immunologist

Tasuku Honjo japanischer Immunologe

Tasuku Honjo Japans immunoloog

Tasuku Honjo japansk immunolog

Тасуку Хонџо јапонски имунолог и нобеловец

Хондзё, Тасуку

Хондзё, Тасуку японский учёный-иммунолог

Хондзьо Тасуку японський учений-імунолог, нобелівський лауреат (2018)

טסוקו הונג'ו

تاسوكو هونجو عالم مناعة ياباني

تاسوکو هونجو

तासुकू हॉन्जो

টাচুকু হঞ্জ'

তাসুকু হনজো

தசுக்கு ஓஞ்சோ

혼조 다스쿠 일본의 면역학자

ホンジョ, タスク

ホンジョ, タスク 1942-

本庶, 佑 1942-

本庶佑 日本の医師、研究者

Languages
English (93)

Japanese (20)