WorldCat Identities

Coughlin, Jennifer M.

Overview
Works: 7 works in 7 publications in 1 language and 10 library holdings
Roles: Other, Author
Publication Timeline
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Most widely held works by Jennifer M Coughlin
The Low-Affinity Binding of Second Generation Radiotracers Targeting TSPO is Associated with a Unique Allosteric Binding Site by Camilo Rojas( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study by Thomas W Sedlak( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET by Jennifer M Coughlin( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Application of the finite element method in the development of improved railroad car wheel designs by T. M Rusin( Book )

1 edition published in 1978 in English and held by 1 WorldCat member library worldwide

Intelligence and Electronic Warfare (IEW) Support for the Corps( Book )

1 edition published in 1984 in English and held by 1 WorldCat member library worldwide

An analysis of the capability of Combat Electronic Warfare and Intelligence (CEWI) units to support the corps and divisions in AirLand Battle is pursued by examining the current structure and equipments fielded. The basic tenets of AirLand Battle -- initiative, agility, depth and synchronization -- are established as valid criteria for evaluating the two structural alternatives presented. The current structure which emphasizes decentralized operations appears to be the better approach given the violence, intensity and confusion that will characterize the modern battlefield. It is concluded that the current CEWI organization has its flaws, centered mostly on equipment and capabilities limitations, but the structure and concept are sound. There are, however, serious equipment limitations that result in gaps in the intelligence capabilities of our forces. Emerging systems under Army 86 will resolve many of the deficiencies but other areas remain to be resolved, including: processing of massive amounts of data, improved Army/USAF cooperation, enhanced survivability of IEW aviation assets, and the development of new aerial platforms. (Author)
Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis A Meta-analysis Using Individual Participant Data by Pontus Plaven-Sigray( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

BACKGROUND: Accumulating evidence suggests that the immune system may be an important target for new treatment approaches in schizophrenia. Positron emission tomography and radioligands binding to the translocator protein (TSPO), which is expressed in glial cells in the brain including immune cells, represents a potential method for patient stratification and treatment monitoring. This study examined whether patients with first-episode psychosis and schizophrenia had altered TSPO levels compared with healthy control subjects. METHODS: PubMed was searched for studies comparing patients with psychosis with healthy control subjects using second-generation TSPO radioligands. The outcome measure was total distribution volume (V-T), an index of TSPO levels, in frontal cortex, temporal cortex, and hippocampus. Bayes factors (BFs) were applied to examine the relative support for higher, lower, or no difference in patients' TSPO levels compared with healthy control subjects. RESULTS: Five studies, with 75 participants with first-episode psychosis or schizophrenia and 77 healthy control subjects, were included. BFs showed strong support for lower VT in patients relative to no difference (all BFs > 32), or relative to higher V-T (all BFs > 422), in all brain regions. From the posterior distributions, mean patient-control differences in standardized V-T values were -0.48 for frontal cortex (95% credible interval [CredInt] = -0.88 to 0.09), -0.47 for temporal cortex (CredInt = -0.87 to -0.07), and -0.63 for hippocampus (CredInt = -1.00 to -0.25). CONCLUSIONS: The lower levels of TSPO observed in patients may correspond to altered function or lower density of brain immune cells. Future studies should focus on investigating the underlying biological mechanisms and their relevance for treatment
California!! : Captain B. Richardson's Overland Route, via Vera Cruz, City of Mexico, and Mazatlan( Book )

1 edition published in 1849 in English and held by 1 WorldCat member library worldwide

 
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.95 (from 0.80 for California ... to 0.99 for Applicatio ...)

Alternative Names
Coughlin, J. M.

Coughlin, Jennifer Marie

Jennifer M Coughlin onderzoeker

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