Jager, D.T. (Dirk Tjalling) 1969-

Hormesis on life-history traits: is there such thing as a free lunch? by Tjalling Jager( )

1 edition published in 2012 in English and held by 2 WorldCat member libraries worldwide

USES 2.0, the Uniform System for the Evaluation of Substances, version 2.0 : the Netherlands' supplement to EUSES( Book )

1 edition published in 1997 in English and held by 2 WorldCat member libraries worldwide

Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans by Suresh Swain( )

1 edition published in 2010 in English and held by 2 WorldCat member libraries worldwide

Uniform system for the evaluation of substances (USES), version 2.0( Book )

2 editions published in 1998 in English and held by 2 WorldCat member libraries worldwide

USES 2.0 is an integrated risk assessment system for new and existing substances and agricultural and non-agricultural pesticides

Automated, high-throughput measurement of size and growth curves of small organisms in well plates by James Duckworth( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Probabilistic risk assessment for new and existing chemicals: sample calculations( Book )

1 edition published in 2000 in English and held by 2 WorldCat member libraries worldwide

Metabolic programming of zebrafish, Danio rerio uncovered : physiological performance as explained by Dynamic Energy Budget theory and life-cycle consequences of uranium induced perturbations by Starrlight Augustine( )

1 edition published in 2012 in English and held by 1 WorldCat member library worldwide

The aim of this dissertation is to characterize the toxicity of depleted uranium (U) on the metabolism of zebrafish, Danio rerio. The underlying hypothesis of this work is that effects of U show up as effects on the metabolism of the individual. Consequently, we characterized physiological performance using Dynamic Energy Budget (DEB) theory since it is the only theory which simultaneously specifies ingestion, assimilation, growth, reproduction, maturation, maintenance and ageing over the whole life-cycle at varying food availability. Thus a DEB model was built which quantifies and predicts how the physiological performance of zebrafish relates to food level (and temperature). We showed that development accelerates after birth until metamorphosis after which acceleration ceases. Furthermore, somatic maintenance costs are very high.A module specifying toxico-kinetics of U in a feeding, growing and reproducing individual was incorporated into the DEB model. The model was then applied to toxicity data (from the literature or acquired during this thesis) in order to determine which processes are affected by U. Our results show that, from 0 nM onwards, U increases costs for growth and either increases somatic maintenance or decreases assimilation. We were unable to detect effects on maturation. A histological study showed that U alters histology of the gut wall and may perturb host-microbe homeostasis. By accounting for differences in initial conditions between individuals we were able to explain a number of seemingly contradictory results. The take home message is: observations on individuals should not be averaged for groups of individuals

EUSES: European Union System for the Evaluation of Substances. EUSES 1.00 user manual + 2 diskettes by Environment Institute (European Commission. Joint Research Centre)( Book )

1 edition published in 1997 in English and held by 1 WorldCat member library worldwide

Uncertainty analysis of EUSES : interviews with representatives from Member States and industry by D.T Jager( Book )

1 edition published in 1998 in English and held by 1 WorldCat member library worldwide

Simplified dynamic energy budget model for analysing ecotoxicity data by Tjalling Jager( )

1 edition published in 2011 in English and held by 0 WorldCat member libraries worldwide