WorldCat Identities

Reszka, Edyta

Overview
Works: 5 works in 5 publications in 2 languages and 6 library holdings
Roles: Author
Publication Timeline
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Most widely held works by Edyta Reszka
Level of selenoprotein transcripts in peripheral leukocytes of patients with bladder cancer and healthy individuals by Edyta Reszka( )

1 edition published in 2009 in Undetermined and held by 2 WorldCat member libraries worldwide

Hypermethylation of p16 and DAPK promoter gene regions in patients with non-invasive urinary bladder cancer( )

1 edition published in 2011 in English and held by 1 WorldCat member library worldwide

Transformacja i detoksykacja herbicydów fenoksylowych w środowisku oraz organizmach żywych( )

1 edition published in 1998 in Polish and held by 1 WorldCat member library worldwide

Społeczeństwo polskie wobec nowych mediów by Edyta Reszka( )

1 edition published in 2010 in Polish and held by 1 WorldCat member library worldwide

DNA damage and methylation induced by glyphosate in human peripheral blood mononuclear cells (invitro study)( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Abstract: Glyphosate is a very important herbicide that is widely used in the agriculture, and thus the exposure of humans to this substance and its metabolites has been noted. The purpose of this study was to assess DNA damage (determination of single and double strand-breaks by the comet assay) as well as to evaluate DNA methylation (global DNA methylation and methylation of p16 (CDKN2A) and p53 (TP53) promoter regions) in human peripheral blood mononuclear cells (PBMCs) exposed to glyphosate. PBMCs were incubated with the compound studied at concentrations ranging from 0.1 to 10mM for 24h. The study has shown that glyphosate induced DNA lesions, which were effectively repaired. However, PBMCs were unable to repair completely DNA damage induced by glyphosate. We also observed a decrease in global DNA methylation level at 0.25mM of glyphosate. Glyphosate at 0.25mM and 0.5mM increased p53 promoter methylation, while it did not induce statistically significant changes in methylation of p16 promoter. To sum up, we have shown for the first time that glyphosate (at high concentrations from 0.5 to 10 mM) may induce DNA damage in leucocytes such as PBMCs and cause DNA methylation in human cells
 
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.97 (from 0.89 for DNA damage ... to 0.99 for Społeczeń ...)

Alternative Names
Edyta Reszka onderzoeker

Edyta Reszka researcher

Reszka, Edyta Wiesława

Languages