WorldCat Identities

Delgado-Mederos, Raquel

Overview
Works: 11 works in 12 publications in 2 languages and 16 library holdings
Roles: Other, Author
Publication Timeline
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Most widely held works by Raquel Delgado-Mederos
Association of High Serum Levels of Growth Factors with Good Outcome in Ischemic Stroke: a Multicenter Study by Tomás Sobrino Chomón( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Comment on the article "Symptomatic carotid near-occlusion causes a high risk of recurrent ipsilateral ischemic stroke" by Gu et al by the Stroke Project of the Spanish Cerebrovascular Diseases Study Group( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Statins do not increase Markers of Cerebral Angiopathies in patients with Cardioembolic Stroke by Joan Martí-Fàbregas( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke by Elena Jiménez-Xarrié( )

1 edition published in 2017 in English and held by 2 WorldCat member libraries worldwide

Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke by Clara Gregori-Pla( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Utilidad del dúplex de arteria temporal y arteria oftálmica en el diagnóstico de la arteritis de células gigantes by Raquel Delgado Mederos( )

1 edition published in 2005 in Spanish and held by 1 WorldCat member library worldwide

Predictores de la evolución clínico-radiológica del ictus isquémico agudo tras tratamiento trombolítico by Raquel Delgado Mederos( Book )

2 editions published between 2008 and 2009 in Spanish and held by 1 WorldCat member library worldwide

In Vivo and Ex Vivo Magnetic Resonance Spectroscopy of the Infarct and the Subventricular Zone in Experimental Stroke( )

in English and held by 1 WorldCat member library worldwide

Ex vivo high-resolution magic-angle spinning (HRMAS) provides metabolic information with higher sensitivity and spectral resolution than in vivo magnetic resonance spectroscopy (MRS). Therefore, we used both techniques to better characterize the metabolic pattern of the infarct and the neural progenitor cells (NPCs) in the ipsilateral subventricular zone (SVZi). Ischemic stroke rats were divided into three groups: G0 (non-stroke controls, n = 6), G1 (day 1 after stroke, n = 6), and G7 (days 6 to 8 after stroke, n =12). All the rats underwent MRS. Three rats per group were analyzed by HRMAS. The remaining rats were used for immunohistochemical studies. In the infarct, both techniques detected significant metabolic changes. The most relevant change was in mobile lipids (2.80 ppm) in the G7 group (a 5.53- and a 3.95-fold increase by MRS and HRMAS, respectively). In the SVZi, MRS did not detect any significant metabolic change. However, HRMAS detected a 2.70-fold increase in lactate and a 0.68-fold decrease in N-acetylaspartate in the G1 group. None of the metabolites correlated with the 1.37-fold increase in NPCs detected by immunohistochemistry in the G7 group. In conclusion, HRMAS improves the metabolic characterization of the brain in experimental ischemic stroke. However, none of the metabolites qualifies as a surrogate biomarker of NPCs
Angiographic and Hemodynamic Effect of High Concentration of Intra-Arterial Nicardipine in Cerebral Vasospasm( )

1 edition published in 2008 in English and held by 1 WorldCat member library worldwide

Abstract OBJECTIVE Nicardipine has been used to treat cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. Intra-arterial (IA) infusion of high concentrations of nicardipine decreases procedure time, but it may affect hemodynamic parameters. In addition, a quantitative measurement of improvement of vessel diameter on the angiograms has not been performed. METHODS We conducted a single-center, retrospective database analysis of consecutive patients with symptomatic vasospasm after aneurysmal subarachnoid hemorrhage who failed medical management and received IA nicardipine between September 2005 and June 2006. Nicardipine (1 mg/mL/min) was infused intra-arterially by microcatheter. Blood pressure, heart rate, and intracranial pressure were recorded during the infusion. The effect of IA nicardipine on the vessel's diameter was measured on angiography by two blinded investigators. RESULTS Forty-six treatment sessions were performed in 22 consecutive patients (13 women; age, 56.4 ±13 years). Fourteen patients received IA nicardipine alone, and 8 patients had additional angioplasty. The average nicardipine dose was 12 ± 10 mg (range, 2-25 mg). The mean decrease of systolic, diastolic, and mean blood pressure was 17.4 ± 18.3 mm Hg, 7.7 ± 10.4 mm Hg, and 10.9 ± 11.6 mm Hg, respectively. There was no change in intracranial pressure. Measurement of 49 vessels in the 14 patients treated with nicardipine alone showed a significant increase in arterial diameters (range, 1-74%; P <0.0001). At the time of discharge, 11 patients (50%) were functionally independent (modified Rankin Scale score, 0-2). CONCLUSION High concentrations of IA nicardipine infusion have a reversible effect on blood pressure and heart rate. IA nicardipine results also in a significant improvement in vessel diameter in patients with vasospasm after aneurysmal subarachnoid hemorrhage
Early risk of recurrent stroke in patients with symptomatic carotid near-occlusion: Results from CAOS, a multicenter registry study( )

in English and held by 1 WorldCat member library worldwide

Background The risk of recurrent stroke among patients with symptomatic carotid near-occlusion is not well established, and management of the condition remains controversial. Symptomatic carotid near-occlusion with full collapse has been identified as a strong predictor of early recurrence. We aimed to analyze the 90-day risk of recurrent ipsilateral ischemic stroke in medically treated patients with symptomatic carotid near-occlusion. Methods We performed a multicenter, nationwide, prospective study from January 2010 to May 2016. Patients with angiography-confirmed symptomatic carotid near-occlusion were included. The primary endpoint was ipsilateral ischemic stroke or transient ischemic attack (TIA) within 90 days after the presenting event. For this analysis, patients who underwent revascularization within 90 days after stroke were excluded. Results The study population comprised 141 patients from 17 Spanish centers; 83 patients were treated medically. Primary endpoint occurred in eight patients, resulting in a cumulative rate of 10.6% (95% CI, 3.7-17.5). Previous history of stroke or transient ischemic attack was identified as an independent predictor for recurrence in the multivariate Cox regression analysis (HR, 4.37 [95% CI, 1.05-18.18]; p = 0.043), while the presence of full collapse was not associated with an increased risk (HR, 0.81 [95% CI, 0.17-3.92]; p = 0.793). The risk of recurrence was also not affected by the presence of significant stenosis or occlusion of the contralateral carotid artery, or by the collateral circulation. Conclusions Patients with symptomatic carotid near-occlusion seem to have an increased risk of early ipsilateral recurrent stroke. Our results contrast with the low risk of symptomatic carotid near-occlusion reported to date. Full collapse did not increase the risk of recurrent stroke in our study
 
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