WorldCat Identities

Hramova, Tatjana

Overview
Works: 2 works in 3 publications in 1 language and 3 library holdings
Genres: Academic theses  Criticism, interpretation, etc 
Roles: Author
Publication Timeline
.
Most widely held works by Tatjana Hramova
The poetics of names in Samuel Beckett's texts by Tatjana Hramova( Book )

2 editions published between 2010 and 2011 in English and held by 2 WorldCat member libraries worldwide

The thesis is an analysis of the aesthetic possibilities of names in literature, with a focus on the names of characters in Samuel Beckett's French and English texts. The initial aim of this research is, therefore, twofold: to produce a study that will show and comment not only on the richness and diversity of Beckett' s naming practices, but also present literary onomastics as an inexhaustible and important source for the aesthetic appreciation of literature. In order to attain these objectives, the thesis gradually moves from the theoretical questions of literary onomastics to the more specific problems of the study of names in Beckett's fiction, eventually coming to the empirical analysis itself that unites the two directions of the research. Adopting the techniques of deconstruction, linguistics and comparative literary studies, the thesis offers a wide range of possible readings of each name, without giving preference to a particular interpretation. Apart from being one of the first attempts to provide a comprehensive critical overview that looks into the history of the study of names in Beckett's texts, this thesis also examines the function and possible meanings of the letters and roots that reappear in the names of Beckett's characters, and explores the means by which names may destabilise and mystify a character, creating a new type of unrepresentability and anonymity. Further, and more broadly, the thesis tries to redefine and re-evaluate literary onomastics, exploring the questions of meaning and reference, discussing the differences between proper and general names and looking into the ways proper names function in a literary text
The idiotypic network in the regulation of autoimmunity: Theoretical and experimental studies( )

1 edition published in 2015 in English and held by 1 WorldCat member library worldwide

Abstract: The regulation of autoimmunity is a key issue in fundamental immunology. Despite outstanding achievements on this front, we currently have more questions than answers. The idea of an immune network as a regulatory mechanism is quite attractive, since it enables us to explain the selectivity (specificity), and moreover the clonality, of the regulation. Nevertheless it remains unclear how this mysterious network of immune cells is organized, how it operates, and how it exerts control over autoimmunity. This article presents an attempt to understand how the immune network functions and how it controls autoreactivity. We present a mathematical model of the immune network that is based on principles of immune network organization and function that we arrived at from a survey of the available literature. To test the principles on which the mathematical model is based, we studied the model and compared the different responses to antigen that it generated with the results obtained from experimental studies of immune response. The modeled kinetics of idiotype and anti-idiotype in response to the administration of antigen are in good agreement with the experimental kinetics of idiotypic and anti-idiotypic antibodies. To obtain evidence of the existence of idiotypic mechanisms for regulating autoimmunity, we studied a mathematical model containing autoclones and compared the model results with data from experimental studies in a model of autoimmune hemolytic anemia in mice. Because the results from the theoretical and the experimental studies coincide, there is justification to conclude that autoreactive lymphocytes are normal components of the immune network within which they are regulated. We discuss a possible molecular/cellular mechanism for negative control of autoreactive cells as affected by anti-idiotypic antibodies
 
Audience Level
0
Audience Level
1
  General Special  
Audience level: 0.81 (from 0.78 for The idioty ... to 0.88 for The idioty ...)

Alternative Names
Khramova, Tatyana

Храмова, Т. (Татьяна)

Храмова, Татьяна

Languages