WorldCat Identities

Arraes, Luiz Claudio

Overview
Works: 3 works in 3 publications in 2 languages and 3 library holdings
Publication Timeline
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Most widely held works by Luiz Claudio Arraes
Rubeola by Sylvia Lemos Hinrichsen( )

1 edition published in 2002 in Portuguese and held by 1 WorldCat member library worldwide

Genotipo MLB2 materno influencia a transmissao vertical em criancas brasileiras by Sergio Crovella( )

1 edition published in 2004 in Portuguese and held by 1 WorldCat member library worldwide

O presente estudo analisa os polimorfismos geneticos no primeiro exon MBL2, em um coorte de 21 pares de maes e filhos infectados por HIV-1 e um coorte de 11 pares constituidos por maes infectadas por HIV-1 e filhos nao infectados, na cidade de Recife(PE), localizada no nordeste do Brasil, com objetivo de avaliar se o genotipo MBL2, de maes infectadas por HIV-1 poderia estar relacionado com transmissibilidade do virus para seus conceptos. Todas criancas nasceram de maes infectadas por HIV-1 que nao haviam recebido nenhum tratamento antiretroviral durante a gravidez e nao foram submetidas a parto cesareano para prevenir transmissao. Maes que transmitiram HIV-1 a seus conceptos (MT) tinham frequencia mais alta (14 porcento) de genotipo 00 no MBL2(tipico de maus produtores de MBL) se comparado com frequencia de 0 porcento observada entre maes infectadas que transmitiram o virus para seus filhos (MNT). Esta diferenca foi estatisticamente significante. A presenca do genotipo 0 e 00 no alelo MBL2 em MT se associou com transmissao viral. O genotipo AA de MBL (associado com producao normal de MBL) teve frequencia de 82 porcento em MNT, significantemente mais alta que a frequencia de 52 porcento de MT. A presenca do alelo A em 91 porcento das MNT conferiu menor risco de transmissao vertical no coorte estudado. Nossos resultados sugerem que a transmissao vertical de HIV-1 depende somente do genotipo MBL2 da crianca e da mae, nas quais os niveis da proteina MBL poderiam desempenhar um importante papel na transmissao do virus
Multicenter study on the immunogenicity and safety of two recombinant vaccines against hepatitis B by Reinaldo Menezes Martins( )

1 edition published in 2004 in English and held by 1 WorldCat member library worldwide

The immunogenicity and safety of a new recombinant hepatitis B vaccine from the Instituto Butantan (Butang[1/2]) were evaluated in a multicenter, double-blind, prospective equivalence study in three centers in Brazil. Engerix B[1/2] was the standard vaccine. A total of 3937 subjects were recruited and 2754 (70 percent) met all protocol criteria at the end of the study. All the subjects were considered healthy and denied having received hepatitis B vaccine before the study. Study subjects who adhered to the protocol were newborn infants (566), children 1 to 10 years old (484), adolescents from 11 to 19 years (740), adults from 20 to 30 years (568), and adults from 31 to 40 years (396). Vaccine was administered in three doses on the schedule 0, 1, and 6 months (newborn infants, adolescents, and adults) or 0, 1, and 7 months (children). Vaccine dose was intramuscular 10 [vbar]g (infants, children, and adolescents) or 20 [vbar]g (adults). Percent seroprotection (assumed when anti-HBs titers were> 10mIU/ml) and geometric mean titer (mIU/ml) were: newborn infants, 93.7 percent and 351.1 (Butang[1/2]) and 97.5 percent and 1530.6 (Engerix B[1/2]); children, 100 percent and 3600.0 (Butang[1/2]) and 97.7 percent and 2753.1 (Engerix B[1/2]); adolescents, 95.1 percent and 746.3 (Butang[1/2]) and 96 percent and 1284.3 (Engerix B[1/2]); adults 20-30 years old, 91.8 percent and 453.5 (Butang[1/2]) and 95.5 percent and 1369.0 (Engerix B[1/2]); and adults 31-40 years old, 79.8 percent and 122.7 (Butang[1/2]) and 92.4 percent and 686.2 (Engerix B[1/2]). There were no severe adverse events following either vaccine. The study concluded that Butang[1/2] was equivalent to Engerix B[1/2] in children, and less immunogenic but acceptable for use in newborn infants, adolescents, and young adults. (AU)
 
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Audience level: 0.99 (from 0.99 for Rubeola ... to 0.99 for Rubeola ...)

Alternative Names
Arraes, Luiz.

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