Advances in cancer research. (Journal, magazine, 1953) [WorldCat.org]
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Advances in cancer research.

Author: ScienceDirect (Online service)
Publisher: New York : Academic Press, 1953-
Edition/Format:   Journal, magazine : Document   Computer File : EnglishView all editions and formats
Summary:
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once agan outstanding and original reviews are presented and include --Book Jacket.
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Genre/Form: Periodicals
Electronic journals
Periodical
Collected Works
Fulltext
Internet Resources
Electronic books
Périodiques
Additional Physical Format: Online version
Advances in cancer research
(DLC) 2011236561
(OCoLC)564421551
Material Type: Document, Internet resource
Document Type: Journal / Magazine / Newspaper, Computer File, Internet Resource
All Authors / Contributors: ScienceDirect (Online service)
ISSN:0065-2407, 0065-230X
OCLC Number: 1057923238
Notes: Contains bibliographies.
Reproduction Notes: Electronic reproduction. : EBL. Available via World Wide Web.
Description: v. : ill. ; 24 cm.
Details: System requirements: Internet connectivity, World Wide Web browser, and Adobe Acrobat reader.
Contents: Machine generated contents note: I.Introduction --
Acknowledgment --
References --
Role of Telomere Dysfunction in Genetic Intratumor Diversity / Laura Tusell --
I.Introduction --
II.Chromosome End Protection: The Shelterin Complex --
III.Telomere Maintenance, Cell Proliferation, and Telomere Uncapping --
IV.Telomeres, Checkpoints, and Cancer --
V.Telomere Uncapping as a Source of Genomic Instability --
VI.Shortening Telomeres in Aged Human Cells --
VII.Summary --
Acknowledgments --
References --
How Mitotic Errors Contribute to Karyotypic Diversity in Cancer / Daniela Cimini --
I.Introduction --
II.Intratumor Diversity at the Karyotypic Level --
III.How mitotic Errors Contribute to the karyotypic Diversity of Cancer Cells --
IV.Conclusion --
Acknowledgments --
References --
Nuclear Remodeling as a Mechanism for Genomic Instability in Cancer / Sabine Mai --
I.Introduction --
II.Imaging Techniques Employed in Nuclear Remodeling Studies Note continued: III.Myc-Dependent Genomic Instability and Nuclear Remodeling --
IV.Nuclear Remodeling and Genomic Instability in Primary Tumors --
V.Models of Genomic Instability Occurring within the Nuclear Space --
VI.Conclusions --
Aknowledgments --
References --
Cytogenetic Analysis of Tumor Clonality / Sverre Heim --
I.Introduction --
II.Cytogenetic Assessment of Clonal Composition of Pancreatic and Large Bowel Tumors --
III.Cytogenetic Assessment of Breast Tumor Clonality --
IV.Cytogenetic Assessment of Urinary Bladder Tumor Clonality --
V.Monoclonal Versus Polyclonal Tumorigenesis: Is the Jury Still Out? --
References --
Genotyping Techniques to Address Diversity in Tumors / Johan Vallon-Christersson --
I.Introduction --
II.The Basic Principles of SNP Array Platforms And SNP Array Data Interpretation --
III.Whole Genome Genotyping of Tumor Samples --
IV.WGG Analyses of Complex and Heterogeneous Cell Populations --
V.Concluding Remarks --
References Note continued: Prostate Cancer as a Model System for Genetic Diversity in Tumors / Anthony M. Joshua --
I.Incidence of Prostate Cancer --
II.Clinical Heterogeneity of Prostate Cancer --
III.Pathology of the Normal Prostate and Prostate Cancer --
IV.Prostate Cancer Oncogenomics --
V.Discovery of TMPRSS2: ETS Fusion Genes in Prostate Cancer --
VI.Frequency of TMPRSS2: ETS Gene Fusions in Prostate Cancer --
VII.Androgen Driven TMPRSS2 Gene Fusions --
VIII.Ets Transcription Factors --
IX.Detection of Fusion Gene Rearrangements by FISH --
X.Loss of PTEN in Prostate Cancer --
XI.Genomic Alterations in Prostate Cancer Preneoplasia --
XII.Genetic Diversity Generated by Telomere Loss in Preneoplasia --
XIII.Chromosomal Instability and Genetic Diversity in Prostate Cancer --
XIV.Multifocal Genotypic Heterogeneity of Prostate Cancer --
XV.Involvement of the Stroma in the Disease Process --
XVI.Stem Cell Origins for Prostate Cancer Note continued: XVII.Prospective: Emerging Insights from Prostate Cancer Genomic Sequencing --
Acknowledgment --
References --
Evolutionary Mechanisms and Diversity in Cancer / Christine J. Ye --
I.Introduction --
II.A Brief Review of Cancer Evolutionary Studies --
III.Genetic Organization and Diversity --
IV.Multiple Levels of Control Systems are Essential for Biological Functions --
V.The Pattern of Evolutionary Dynamics of Somatic Cell Evolution --
VI.The Evolutionary Mechanism of Cancer and its Medical Implications --
Acknowledgments --
References --
Cancer Stem Cells in Tumor Heterogeneity / Alexander Pietras --
I.Introduction --
II.A Brief Introduction to Models of Tumor Development --
III.Evidence for a Role of Cancer Stem Cells in Phenotypic Tumor Cell Heterogeneity --
IV.Clues from Metastatic and Recurring Lesions --
V.Cancer Stem Cells and Endothelial/Stromal Differentiation --
VI.Cancer Stem Cells in Angiogenesis Note continued: VII.Cancer Stem Cells in Heterogeneity of the Therapeutic Response --
VIII.Unresolved Issues Regarding the Cancer Stem Cell Model in Tumor Heterogeneity --
IX.Future Directions --
Acknowledgments --
References --
Cancer: Beyond Speciation / Mark D. Vincent --
I.Introduction --
II.How To "Understand" Cancer --
III."Conventional Wisdom": The Darwinian View of Cancer --
IV.Alternative Interpretations of Cancer --
V.Cancer as Speciation: Implications for Biology and Therapy --
VI.Beyond Speciation: The Nature of Cancer --
VII.The Nature of Cancer: A Trait-Based Inferential Approach --
VIII.Resistance to Therapy: The Long Arm of The Proterozoic --
IX.Is There an Answer? --
X.What Form of Life? --
References.
Other Titles: Advances in cancer research

Abstract:

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once agan outstanding and original reviews are presented and include --Book Jacket.

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