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Alcoholic/non-alcoholic digestive diseases

Author: Hitoshi Yoshiji; Kosuke Kaji
Publisher: Singapore : Springer, [2019]
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Yoshiji, Hitoshi
Alcoholic/Non-Alcoholic Digestive Diseases
Singapore : Springer,c2019
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Hitoshi Yoshiji; Kosuke Kaji
ISBN: 9789811314650 9811314659
OCLC Number: 1104725950
Notes: Includes index.
7.1 Prevalence of Impaired Glucose Tolerance (IGT) and Diabetes Mellitus in Patients with Chronic Liver Disease (CLD)
Description: 1 online resource
Contents: Intro; Preface; Contents; Part I: Alcoholic/Non-Alcoholic Gastrointestinal Diseases; Chapter 1: Alcohol-Induced DNA Injury in Esophageal Squamous Cell Carcinoma; 1.1 Acetaldehyde, a Metabolite of Alcohol, and the Development of Esophageal Squamous Cell Carcinoma; 1.2 Blood and Saliva Acetaldehyde Concentration After Alcohol Intake; 1.3 Acetaldehyde Reacts with DNA to Form DNA Adducts and Cause Severe DNA Damage; 1.4 Conclusions; References; Chapter 2: Gastroesophageal Reflux Diseases and Lifestyle Factors; 2.1 Introduction; 2.2 Obesity; 2.3 Metabolic Syndrome; 2.4 Diabetes Mellitus 2.5 Hypertension2.6 Dyslipidemia; 2.7 Cigarette Smoking; 2.8 Alcohol Drinking; 2.9 Late Meal; 2.10 Conclusions; References; Chapter 3: Post Helicobacter pylori Gastric Diseases; 3.1 H. pylori-Negative Mucosal Injury of the Stomach; 3.1.1 H. pylori-Negative Gastric Ulcer; 3.1.2 Drug-Induced Gastric Ulcer (Recurrent Gastric Ulcer) After H. pylori Eradication; 3.2 Inflammation (Gastritis) and Acid Secretion; 3.3 Functional Dyspepsia Defined without H. pylori Infection: Hypersensitive Mucosa to Acid Exposure; 3.4 Association of Non-alcoholic Fatty Liver Disease with Gastroesophageal Diseases 3.5 ConclusionsReferences; Chapter 4: New Perspectives in Gastric Cancer: Helicobacter pylori-Uninfected Pure Signet Ring Cell Carcinoma; 4.1 Introduction; 4.2 Diagnostic Criteria for HP-Uninfected Gastric Cancer; 4.3 Characteristics of HP-Uninfected Intramucosal Pure Signet Ring Cell Carcinoma; 4.3.1 Case Presentation of HDGC; 4.3.2 HP-Uninfected Pure Signet Ring Cell Carcinoma; 4.4 Speculation about the Carcinogenic Mechanisms of HP-Uninfected Pure Signet Ring Cell Carcinoma; 4.5 Future Directions; References; Chapter 5: Role of Alcohol and Metabolic Diseases in Colorectal Carcinogenesis 5.1 Colorectal Cancer Risk Attributable to Alcohol5.2 Risk for Precancerous Lesions in the Colorectum Attributable to Alcohol; 5.3 Developmental Mechanism of Colorectal Cancer Attributable to Alcohol; 5.4 Metabolic Syndrome and Colorectal Cancer Risk; 5.5 Colorectal Cancer Risk Attributable to Metabolic Syndrome; 5.6 Risk for Precancerous Lesions in the Colorectum Attributable to Metabolic Syndrome; 5.7 Four Components of Metabolic Syndrome and Colorectal Cancer Risk; 5.8 Developmental Mechanism of Colorectal Cancer Attributable to Metabolic Syndrome; 5.9 Epilogue; References Part II: Alcoholic/Non-Alcoholic Liver DiseasesChapter 6: Extracellular Vesicles in Alcoholic Liver Injury; 6.1 Introduction; 6.1.1 Alcoholic Liver Injury; 6.1.2 Extracellular Vesicles (EVs); 6.2 The Mechanism of EV Release and the Role of EVs in ALD/ASH; 6.2.1 Hepatocyte-Derived Extracellular Vesicles (Hep-EVs); 6.2.2 Non-parenchymal Cell-Derived Extracellular Vesicles; 6.3 EVs as Novel Biomarkers to Monitor Liver Injury in ALD/ASH; 6.3.1 Ligands and Proteins; 6.3.2 mtDNAs and miRNAs; 6.4 Conclusions; References; Chapter 7: Diabetes in Liver Disease
Responsibility: Hitoshi Yoshiji, Kosuke Kaji, editors.

Abstract:

This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases.  Read more...

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