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Aminoglycoside antibiotics : from chemical biology to drug discovery

Author: D P Arya
Publisher: Hoboken, N.J. : Wiley-Interscience, ©2007.
Series: Wiley series in drug discovery and development.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Advances that open new avenues in developing aminoglycoside antibiotics During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: D P Arya
ISBN: 9780471743026 047174302X
OCLC Number: 144525705
Description: x, 319 pages, [8] pages of plates : illustrations (some color) ; 25 cm.
Contents: In the beginning there was streptomycin / Julian Davies --
The biochemistry and genetics of aminoglycoside producers / Wolfgang Piepersberg [and others] --
Mechanisms of aminoglycoside antibiotic resistance / Tushar Shakya and Gerard D. Wright --
Design, chemical synthesis and antibacterial activity of kanamycin and neomycin class aminoglycoside antibiotics / Jinhua Wang and Cheng-Wei Tom Chang --
NMR structural studies of aminoglycoside : RNA interaction / R. Andrew Marshall and Joseph D. Puglisi --
Structural comparisons between prokaryotic and eukaryotic ribosomal decoding a sites free and complexed with aminoglycosides / Jiro Kondo and Eric Westhof --
Binding of antibiotics to the aminoacyl-tRNA site of bacterial ribosome / Dale King, Christine Chow and Shahriar Mobashery --
Metalloaminglycosides : chemistry and biological relevance / Nikhil Gokhale, Anjali Patwardhan and J.A. Cowan --
Adverse effects of aminoglycoside therapy / Andra E. Talaska and Jochem Schacht --
Targeting HIV-1 RNA with aminoglycoside antibiotics and their derivatives / Lev Elson-Schwab and Yitzhak Tor --
Novel targets for aminoglycosides / Dev P. Arya, Nicholas Shaw and Honjuan Xi.
Series Title: Wiley series in drug discovery and development.
Responsibility: Dev P. Arya.
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"This is a 'must-have' text for anyone involved in AGA teaching or research. No better comprehensive treatise exists..." (Journal of Medicinal Chemistry, October 18, 2007) "There is little Read more...

 
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