Analogue-based drug discovery (eBook, 2006) []
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Analogue-based drug discovery

Author: János Fischer; C R Ganellin
Publisher: Weinheim : Wiley-VCH, ©2006.
Edition/Format:   eBook : Document : EnglishView all editions and formats
The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Analogue-based drug discovery.
Weinheim : Wiley-VCH, ©2006
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: János Fischer; C R Ganellin
ISBN: 9783527607495 3527607498 9783527312573 3527312579 3527608001 9783527608003
OCLC Number: 77601762
Description: 1 online resource (xxxi, 575 pages) : illustrations
Contents: Analogue-based Drug Discovery; Contents; Preface; Introduction; List of Contributors; Abbreviations; Part I General Aspects of Analogue-Based Drug Discovery; 1 Analogues as a Means of Discovering New Drugs; 2 Drug Likeness and Analogue-Based Drug Discovery; 3 Privileged Structures and Analogue-Based Drug Discovery; Part II Selected Examples of Analogue-Based Drug Discoveries; 1 Development of Anti-Ulcer H(2)-Receptor Histamine Antagonists; 2 Esomeprazole in the Framework of Proton-Pump Inhibitor Development; 3 The Development of a New Proton-Pump Inhibitor: The Case History of Pantoprazole.
Responsibility: edited by János Fischer and C. Robin Ganellin.


Provides an overview of strategies for successful drug development by analog generation. This book covers various important drug classes and major therapeutic fields, including histamine antagonists,  Read more...


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"...eminently capable of educating both newcomers and experienced practitioners...highly recommended as an addition to the personal collection of the practicing drug designers and as a reference for Read more...

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