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Antibodies, their structure and function

Author: M W Steward
Publisher: London ; New York : Chapman and Hall, 1984.
Series: Outline studies in biology (Chapman and Hall)
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his  Read more...

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Document Type: Book
All Authors / Contributors: M W Steward
ISBN: 0412256401 9780412256400
OCLC Number: 10185345
Description: 96 pages : illustrations ; 22 cm.
Contents: 1 Introduction.- 2 Isolation and purification of immunoglobulins and specific antibodies.- 2 1 Induction of serum antibodies.- 2.2 Isolation of immunoglobulins.- 2.3 Isolation of specific antibodies.- 2.4 Monoclonal antibodies produced by hybrid myelomas (hybridomas).- References.- 3 General structure of immunoglobulins.- 3.1 The basic four chain model for IgG.- 3.2 Immunoglobulins are glycoproteins.- 3.3 Amino acid sequence studies.- 3.4 The antibody binding site.- 3.5 Immunoglobulin domains.- 3.6 Allotypes and idiotypes of immunoglobulins.- References.- 4 Antibod -antigen interaction.- 4.1 The intermolecular forces involved in antibody-antigen interactions.- 4.2 The measurement of antibody-antigen reactions.- 4.3 The study of the chemistry of antibody-antigen reactions.- 4.4 The thermodynamics of antibody-antigen reactions.- 4.5 The kinetics of the antibody-antigen reactions.- 4.6 The biological aspects of antibody affinity.- 4.7 The specificity and cross-reactivity of antibody-antigen interactions.- References.- 5 Structure and biological activities of the immunoglobulin classes.- 5.1 Immunoglobulin G.- 5.2 Immunoglobulin A.- 5.3 Immunoglobulin M.- 5.4 Immunoglobulin E.- 5.5 Immunoglobulin D.- 5.6 Effector functions of antibodies.- References.- 6 The control of antibody production.- 6.1 The synthesis and secretion of antibody molecules.- 6.2 The genetic control of antibody biosynthesis.- 6.3 The generation of antibody diversity.- References.
Series Title: Outline studies in biology (Chapman and Hall)
Responsibility: M.W. Steward.

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Professor Steward's book...provides up-to-date coverage of all the most important considerations of the structure, synthesis and function in the sort of detail that few larger textbooks can match. Read more...

 
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