Applied Biopharmaceutics and Pharmacokinetics (Book, 1999) []
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Applied Biopharmaceutics and Pharmacokinetics

Applied Biopharmaceutics and Pharmacokinetics

Author: Leon Andrew Shargel
Publisher: London : Appleton, 1999.
Edition/Format:   Print book : EnglishView all editions and formats

This work emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, pharmacodynamics, metabolism and drug delivery.


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Document Type: Book
All Authors / Contributors: Leon Andrew Shargel
ISBN: 0838502784 9780838502785
OCLC Number: 909421494
Description: 768 p. ; 23 cm
Contents: Mathematical fundamentals on pharmacokinetics; introduction to biopharmaceutics and pharmacokinetics; one compartment model; physiological factors relating to drug absorption; biopharmaceutic considerations in drug product design; modified release drug products; delivery of biotechnical products and targetted drug delivery systems; pharmacokinetics of drug absorption; bioavailability and bioequivalence; multicompartmental models; drug distribution and protein binding; drug clearance; drug metabolism and hepatic clearance; pharmacokinetics after intravenous infusion; pharmacokinetics after multiple dosing; non-linear pharmacokinetics; introduction to clinical pharmacokinetics; application of pharmacokinetics to clinical situations; relationship between pharmacokinetic parameters and pharmacologic response; physiologic pharmacokinetic model and statistical moment; computer applications in pharmacokinetics; biopharmaceutics and pharmacokinetic studies in drug development; appendix.
Responsibility: Andrew Leon Shargel.


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