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Ayurvedic preparation of <i>Zingiber officinale</i> Roscoe: effects on cardiac and on smooth muscle parameters
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Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters

Author: Alberto Leoni Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, ItalyRoberta Budriesi Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, ItalyFerruccio Poli Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, ItalyMariacaterina Lianza Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, ItalyAlessandra Graziadio Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, ItalyAll authors
Edition/Format: Article Article
Publication:Natural Product Research, v32 n18 (20180917): 2139-2146
Summary:
The rhizome of the Zingiber officinale Roscoe, a biennial herb growing in South Asia, is commonly known as ginger. Ginger is used in clinical disorders, such as constipation, dyspepsia, diarrhoea, nausea and vomiting and its use is also recommended by the traditional medicine for cardiopathy, high blood pressure, palpitations and as a vasodilator to improve the circulation. The decoction of ginger rhizome is widely  Read more...
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Details

Document Type: Article
All Authors / Contributors: Alberto Leoni Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, Italy; Roberta Budriesi Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, Italy; Ferruccio Poli Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, Italy; Mariacaterina Lianza Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, Italy; Alessandra Graziadio Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, Italy; Alice Venturini Affiliation: Educational Laboratory ex Lolli Hospital, School of Farmacy, Biotechnology and Sport Science, Imola, Italy; Massimiliano Broccoli Affiliation: Educational Laboratory ex Lolli Hospital, School of Farmacy, Biotechnology and Sport Science, Imola, Italy; Matteo Micucci Affiliation: Department of Farmacy and Biotecnology, AlmaMater Studiorum- University of Bologna, Bologna, Italy
ISSN:1478-6419
Unique Identifier: 7810783964
Notes: research-article
Awards:

Abstract:

The rhizome of the Zingiber officinale Roscoe, a biennial herb growing in South Asia, is commonly known as ginger. Ginger is used in clinical disorders, such as constipation, dyspepsia, diarrhoea, nausea and vomiting and its use is also recommended by the traditional medicine for cardiopathy, high blood pressure, palpitations and as a vasodilator to improve the circulation. The decoction of ginger rhizome is widely used in Ayurvedic medicine. In this papery by high-performance liquid chromatography, we have seen that its main phytomarkers were 6-gingerol, 8-gingerol and 6-shogaol and we report the effects of the decoction of ginger rhizome on cardiovascular parameters and on vascular and intestinal smooth muscle. In our experimental models, the decoction of ginger shows weak negative inotropic and chronotropic intrinsic activities but a significant intrinsic activity on smooth muscle with a potency on ileum is greater than on aorta: EC50 = 0.66 mg/mL versus EC50 = 1.45 mg/mL.

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