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Biomedical technology : modeling, experiments and simulation

Author: P Wriggers; Thomas Lenarz
Publisher: Cham, Switzerland : Springer, [2018] ©2018
Series: Lecture notes in applied and computational mechanics, v. 84.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges. The first part focuses on the virtual environment used to study biological systems at different scales and under multiphysics conditions. In turn, the second part is devoted to modeling and computational  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: P Wriggers; Thomas Lenarz
ISBN: 9783319595481 3319595482
OCLC Number: 1002418536
Description: 1 online resource
Contents: Preface; Contents; Part I Biological Systems; Multiscale Aspects in the Multiphasic Modelling of Human Brain Tissue ; 1 Introduction and Motivation; 2 Anatomic Elements of Human Brain Tissue; 3 TPM Model of the Overall Brain-Tissue Aggregate; 4 Microscopically Underlaid Macroscopic Constitutive Relation; 4.1 Microscopic Model Settings; 4.2 Macroscopic Constitutive Relation; 4.3 Results and Discussion; References; Simulation of Steatosis Zonation in Liver Lobule --
A Continuummechanical Bi-Scale, Tri-Phasic, Multi-Component Approach; 1 Introduction; 2 Glucose and Fat Metabolism. 3 Numerical Example: Comparison of Different Assumptions for the Perfusion Coupled to the Metabolism3.1 Discussion; References; 3 Nano-Mechanical Tensile Behavior of the SPTA1 Gene in the Presence of Hereditary Hemolytic Anemia-Related Point Mutations; Abstract; 1 Introduction; 2 Spectrin Structure; 3 Materials and Methods; 4 Results; 5 Discussion; Acknowledgements; References; The Choice of a Performance Indicator of Release in Transdermal Drug Delivery Systems ; 1 Introduction; 2 The Concept of an Effective Time Constant: Definition and Applications; 3 A One-Layer Model for TDD. 4 Computation of the ETC for a One-Layer Skin Model5 A Multi-layer Model for TDD; 6 Computation of the ETC for a Multi-layer Skin Model; 7 Computational Results; 8 Conclusions; References; Part II Cardiovascular Medicine; 5 Multiscale Multiphysic Approaches in Vascular Hemodynamics; Abstract; 1 Introduction; 2 Geometry Creation and General Simulation Settings; 3 Boundary Conditions; 3.1 Lumped Parameter Modeling; 3.2 0-D/3-D Coupling; 4 Fluid-Structure-Interaction; 4.1 0-D/3-D Coupling of FSI Simulations; 5 Examples; 5.1 An FSI Model of Cardiopulmonary Bypass with Cerebral Autoregulation. 5.2 A CFD Model of VAD Support Using Closed-Loop Multiscale Simulations to Evaluate Various Cannulation Strategies5.3 A Numerical Framework to Investigate Hemodynamics During Endovascular Mechanical Recanalization in Acute Stroke; 6 Conclusion; References; Heart Valve Flow Computation with the Space --
Time Slip Interface Topology Change (ST-SI-TC) Method and Isogeometric Analysis (IGA); 1 Introduction; 2 ST-VMS and ST-SI Formulations; 2.1 ST-VMS Formulation; 2.2 ST-SI Formulation; 3 ST-SI-TC-IGA Method; 3.1 ST-SI Method; 3.2 ST-TC Method; 3.3 ST-IGA Method. 3.4 Integration of the ST-SI, ST-TC and ST-IGA Methods4 Aortic-Valve Model; 4.1 Geometry; 4.2 Mesh and Flow Conditions; 4.3 Computational Conditions; 4.4 Results; 5 Concluding Remarks; References; Estimation of Element-Based Zero-Stress State in Arterial FSI Computations with Isogeometric Wall Discretization ; 1 Introduction; 2 Element-Based Total Lagrangian (EBTL) Method; 2.1 EBZSS; 2.2 NURBS Basis Functions; 2.3 EBZSS Representation with NURBS Basis Functions; 3 Modeling the Artery ZSS: Straight-Tube ZSS Template; 4 2D Test Computations; 4.1 Meshes; 4.2 Curvature Matching in the ZSS.
Series Title: Lecture notes in applied and computational mechanics, v. 84.
Responsibility: Peter Wriggers, Thomas Lenarz, editors.

Abstract:

This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and  Read more...

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