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Bioreactors for Stem Cell Expansion and Differentiation

Author: Joaquim S Cabral; Cláudia L da Silva
Publisher: Boca Raton, FL : CRC Press, [2019]
Series: Gene and cell therapy series.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological  Read more...
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Details

Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Joaquim S Cabral; Cláudia L da Silva
ISBN: 9780429453144 0429453140 9781498795913 1498795919 9780429841828 0429841825 9780429841811 0429841817 9780429841804 0429841809
OCLC Number: 1055160540
Description: 1 online resource.
Contents: Expansion of human pluripotent stem cells in microcarrier-based culture systems. Large-scale culture of 3D aggregates of pluripotent stem cells. Cardiac differentiation of human pluripotent stem cells in scalable suspension culture. Integrated processes for expansion and differentiation of human pluripotent stem cells into neural progenitor cells. Bioreactor protocols for human neural precursor cell expansion. Expansion of human cardiac progenitor cells in using microcarriers. Differentiation of embryonic stem cells towards red blood cell production. Expansion of hematopoietic progenitor cells in a hollow fiber bioreactor system. Engineering the bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis. Packed Bed Bioreactor for the Isolation and Expansion of Human Mesenchymal Stem/Stromal Cells. Expansion of human mesenchymal stem/stromal cells in microcarrier-based culture systems. Scaffold-based perfusion bioreactors for Cell Therapies and Tissue Engineering. Vascular Tissue Engineering. Bioreactor design for bone and cartilage tissue engineering. Engineering cardiac tissue in bioreactors. Organ-level tissue engineering using bioreactor systems and stem cells. Kidney Tissue Engineering. Liver Tissue Engineering. Bioprocess monitoring in tissue engineering perfusion bioreactors. Bioprocessing of human stem cells for therapeutic use through single-use bioreactors.
Series Title: Gene and cell therapy series.
Responsibility: edited by Joaquim M.S. Cabral, Claudia Lobato da Silva.

Abstract:

An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization. This book in the fields of stem cell expansion, bioreactors, bioprocessing, and bio and tissue engineering, gives the reader a full understanding of the state-of-art and the future of these fields.

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