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Cellular biophysics and modeling : a primer on the computational biology of excitable cells

Author: Greg Conradi Smith
Publisher: Cambridge ; New York, NY : Cambridge University Press, 2019. ©2019
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"It must also be supposed that the cell bodies and the dendrites are, in the same way as the axis cylinders, conductive devices, as they represent the intermediary links between afferent nerve fibres and the afore-mentioned axons"--
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Additional Physical Format: ebook version :
Document Type: Book
All Authors / Contributors: Greg Conradi Smith
ISBN: 9781107005365 1107005361 9780521183055 0521183057
OCLC Number: 1055457368
Description: xii, 382 pages ; 25 cm
Contents: Compartmental modeling --
Phase diagrams --
Ligands, receptors & rate laws --
Function families & characteristic times --
Bifurcation diagrams of scalar ODEs --
The Nernst equilibrium potential --
The current balance equation --
GHK theory of membrane permeation --
Voltage-gated ionic currents --
Regenerative ionic currents and bistability --
Voltage-clamp recording --
Hodgkin-Huxley model of the action potential --
The Morris-Lecar model --
Phase plane analysis --
Linear stability analysis --
Type II excitability and oscillations (the Hopf bifurcation) --
Type I excitability and oscillations (SNIC & SHO bifurcations) --
The low-threshold calcium spike --
Synaptic currents.
Responsibility: Greg Conradi Smith.

Abstract:

An integrated guide to cellular biophysics and nonlinear dynamics, introducing students to the mathematical modeling of excitable cells. It combines empirical physiology and mathematical theory to  Read more...

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'In this text, Conradi Smith does an excellent job of teaching students with no mathematical training beyond calculus how to use differential equations to understand the basic principles of cell Read more...

 
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