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Cholesterol modulation of protein function : sterol specificity and indirect mechanisms

Author: Avia Rosenhouse-Dantsker; Anna N Bukiya
Publisher: Cham, Switzerland : Springer, 2019.
Series: Advances in experimental medicine and biology, v. 1115.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is  Read more...
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Details

Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Avia Rosenhouse-Dantsker; Anna N Bukiya
ISBN: 9783030042783 3030042782
OCLC Number: 1083260823
Description: 1 online resource (x, 197 pages) : illustrations (some color)
Contents: Sterol specificity in modulating protein function. Chirality effect on cholesterol modulation of protein function / Jitendra D. Belani --
A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs / Md. Jafurulla, G. Aditya Kumar, Bhagyashree D. Rao, Amitabha Chattopadhyay --
Regulation of BK channel activity by cholesterol and its derivatives / Anna N. Bukiya, Alex M. Dopico --
Chiral specificity of cholesterol orientation within cholesterol binding sites in inwardly rectifying K+ channels / Nicolas Barbera, Irena Levitan --
Indirect modulation of protein function by cholesterol. Cholesterol effects on the physical properties of lipid membranes viewed by solid-state NMR spectroscopy / Trivikram R. Molugu, Michael F. Brown --
Effect of cholesterol on the dipole potential of lipid membranes / Ronald J. Clarke --
Mass spectrometry imaging of cholesterol / Stephanie M. Cologna --
Cholesterol-dependent gating effects on ion channels / Qiu-Xing Jiang.
Series Title: Advances in experimental medicine and biology, v. 1115.
Responsibility: Avia Rosenhouse-Dantsker, Anna N. Bukiya, editors.

Abstract:

In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels.  Read more...

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