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Circular RNAs : biogenesis and functions

Author: Junjie Xiao
Publisher: Singapore : Springer, [2018] ©2018
Series: Advances in experimental medicine and biology, v. 1087.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Provides an essential overview of the rapidly advancing field of circular RNAs -- newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs' biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Circular RNAs.
Singapore : Springer, [2018]
(OCoLC)1039669264
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Junjie Xiao
ISBN: 9789811314261 9811314268 9789811314278 9811314276
OCLC Number: 1055433331
Description: 1 online resource : color illustrations.
Contents: Overview. An overview of circular RNAs / Rajendra Awasthi, Anurag Kumar Singh, Gaurav Mishra, Anand Maurya, Dinesh Kumar Chellappan, Gaurav Gupta [and others] --
Bioinformatics for circular RNAs. RNA sequencing and prediction tools for circular RNAs analysis / Elena López-Jiménez, Ana M. Rojas, Eduardo Andrés-León --
Online databases and circular RNAs / Seyed Hamid Aghaee-Bakhtiari --
Biogenesis of circular RNAs. Circular RNA splicing / Nicole Eger, Laura Schoppe, Susanne Schuster, Ulrich Laufs, Jes-Niels Boeckel --
Circular RNAs biogenesis in eukaryotes through self-cleaving hammerhead ribozymes / Marcos de la Peña --
Molecular mechanisms and gene regulation of circular RNAs. circular RNAs act as mirna sponges / Amaresh Chandra Panda --
Regulation of transcription by circular RNAs / Rumela Bose, Rupasri Ain --
Functional analysis of circular RNAs / Shanmugapriya, Hisham Alkatib Huda, Soundararajan Vijayarathna, Chern Ein Oon, Yeng Chen, Jagat R. Kanwar [and others] --
Circular RNAs as potential disease biomarkers. Circular RNA in exosomes / Daniele Fanale, Simona Taverna, Antonio Russo, Viviana Bazan --
Circular RNAs in blood / Angela Vea, Vicenta Llorente-Cortes, David de Gonzalo-Calvo --
Circular RNA in saliva / Farinaz Jafari Ghods --
Emerging role of circular RNAs as potential biomarkers for the diagnosis of human diseases / Rupal Ojha, Raj Nandani, Nina Chatterjee, Vijay Kumar Prajapati --
Circular RNAs as novel biomarkers for cardiovascular diseases / Qiulian Zhou, Zhongrong Zhang, Yihua Bei, Guoping Li, Tianhui Wang --
Circular RNAs as biomarkers for cancer / Lu Xia, Meiyi Song, Mengxue Sun, Fei Wang, Changqing Yang --
Circular RNAs and human diseases. Circular RNAs in cardiovascular diseases / Lijun Wang, Xiangmin Meng, Guoping Li, Qiulian Zhou, Junjie Xiao --
Circular RNAs and neuronal development / Lena Constantin --
Circular RNAs in cancer / Susanne Lux, Lars Bullinger --
Circular RNAs in brain physiology and disease / S. Gokul, G.K. Rajanikant --
Circular RNA and alzheimer's disease / Rumana Akhter --
Circular RNA in liver: health and diseases / Meiyi Song, Lu Xia, Mengxue Sun, Changqing Yang, Fei Wang --
Circular RNAs in organ fibrosis / Jianhua Yao, Qiying Dai, Zhuyuan Liu, Lei Zhou, Jiahong Xu --
Circular RNAs in metabolic diseases / Tianhui Wang, Wen Pan, Jun Hu, Zhongrong Zhang, Guoping Li, Yajun Liang --
Circular RNAs in vascular functions and diseases / Shengguang Ding, Yujiao Zhu, Yajun Liang, Haitao Huang, Yiming Xu, Chongjun Zhong --
Functional role of circular RNA in regenerative medicine / Richard Y. Cao, Qiying Dai, Qing Li, Jian Yang --
The role of circular RNAs in cerebral ischemic diseases: ischemic stroke and cerebral ischemia/reperfusion injury / Jian Yang, Mengli Chen, Richard Y. Cao, Qing Li, Fu Zhu --
Circular RNAs in plants and in archaea. Circrnas in plants / Xuelei Lai, Jérémie Bazin, Stuart Webb, Martin Crespi, Chloe Zubieta, Simon J. Conn --
Circular RNAs and plant stress responses / Celso Gaspar Litholdo Jr., Guilherme Cordenonsi da Fonseca --
Future prospects. Prospective advances in circular RNA investigation / Siti Aishah Sulaiman, Nor Azian Abdul Murad, Ezanee Azlina Mohamad Hanif, Nadiah Abu, Rahman Jamal.
Series Title: Advances in experimental medicine and biology, v. 1087.
Responsibility: Junjie Xiao, editor.

Abstract:

Provides an essential overview of the rapidly advancing field of circular RNAs -- newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs' biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have numerous potential functions. The book consists of eight parts:1) An overview of circular RNAs, 2) Bioinformatics for circular RNAs, 3) Biogenesis of circular RNAs, 4) Molecular mechanisms and gene regulation of circular RNAs, 5) Circular RNAs as potential disease biomarkers, 6) Circular RNAs and human diseases, 7) Circular RNAs in Plants and in Archaea, and 8) Future prospects. Given its focus, the book will be especially useful for researchers and students in the fields of biochemistry, molecular biology, cell biology, and medicine.

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