Clinical pharmacokinetics and pharmacodynamics : concepts and applications (Book, 2011) [WorldCat.org]
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Clinical pharmacokinetics and pharmacodynamics : concepts and applications
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Clinical pharmacokinetics and pharmacodynamics : concepts and applications

Author: Malcolm Rowland; Thomas N Tozer
Publisher: Philadelphia : Wolters Kluwer Health/Lippincott William & Wilkins, ©2011.
Edition/Format:   Print book : English : 4th edView all editions and formats
Summary:
"Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the  Read more...
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Details

Document Type: Book
All Authors / Contributors: Malcolm Rowland; Thomas N Tozer
ISBN: 9780781750097 0781750091
OCLC Number: 426115435
Notes: Revised edition of: Clinical pharmacokinetics. 1995.
Includes index.
Description: xxii, 839 pages : illustrations ; 26 cm
Contents: Therapeutic relevance --
Fundamental concepts and terminology --
Kinetics following an intravenous bolus dose --
Membranes and distribution --
Elimination --
Kinetics following an extravascular dose --
Absorption --
Response following a single dose --
Therapeutic window --
Constant-rate input --
Multiple-dose regimens --
Variability --
Genetics --
Age, weight, and gender --
Disease --
Nonlinearities --
Drug interactions --
Initiating and managing therapy --
Distribution kinetics --
Metabolites and drug response --
Protein drugs --
Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.
Responsibility: Malcolm Rowland, Thomas N. Tozer.

Abstract:

Reflects the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This title also reflects the explosion in our  Read more...

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-- "This textbook covers a tremendous range of topics important in pharmacokinetics and pharmacodynamics. No other textbook does this as effectively as the Rowland and Tozer text." -- "I believe Read more...

 
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