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Clinical trials : a methodologic perspective

Author: Steven Piantadosi
Publisher: Hoboken, NJ : John Wiley & Sons, Inc., 2017. ©2017
Series: Wiley series in probability and statistics.
Edition/Format:   Print book : English : Third editionView all editions and formats
Summary:

This Third Edition of the critically hailed Clinical Trials builds on the text's reputation as a straightforward and authoritative presentation of statistical methods for clinical trials.

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Details

Document Type: Book
All Authors / Contributors: Steven Piantadosi
ISBN: 9781118959206 1118959205
OCLC Number: 964437412
Description: xxviii, 886 pages ; 27 cm.
Contents: Preliminaries --
Clinical Trials as research --
Why Clinical Trials are ethical --
Context for Clinical Trials --
Context for clinicak tricals --
Measurement --
Random error and bias --
Statistical perspectives --
Experiment design in clinical trials --
The trial cohort --
Development paradigms --
Translational clinical trials --
Early development and dose-finding --
Middle Development --
Comparative trials --
Adaptive design features --
Sample size and power --
Treatment allocation --
Treatment effects monitoring --
Counting subjects and events --
Estimating clinical effects --
Prognostic factor analyses --
Factorial design --
Crossover Designs --
Meta-analyes --
Reporting and authorship --
Misconduct and fraud in clinical research --
Appendix A Data and programs --
Appendix B Abbreviations --
Appendix C Notation and Terminology --
Appendix D Nuremberg code --
References --
Index.
Series Title: Wiley series in probability and statistics.
Responsibility: Steven Piantadosi.

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