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Computational anatomical animal models : methodological developments and research applications

Author: Habib Zaidi; Institute of Physics (Great Britain),
Publisher: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2018]
Series: IOP expanding physics.; IPEM-IOP series in physics and engineering in medicine and biology.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Computational Anatomical Animal Models: Methodological developments and research applications provides a comprehensive review of the history and technologies used for the development of computational small animal models with a focus on their application in preclinical imaging and experimental radiation therapy, as well as non-ionizing and ionizing radiation dosimetry calculations. It also provides an overview of the  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Habib Zaidi; Institute of Physics (Great Britain),
ISBN: 9780750313445 0750313447 9780750313469 0750313463 0750313455 9780750313452
OCLC Number: 1082881975
Notes: "Version: 20181201"--Title page verso.
Description: 1 online resource : illustrations (chiefly color).
Contents: part I. Computational models. 1. Historical development and overview of computational animal models --
1.1. Introduction --
1.2. Construction of computational models --
1.3. Overview of existing computational animal models --
1.4. Popular simulation tools for computational models --
1.5. Summary 2. Design and construction of computational animal models --
2.1. Introduction --
2.2. Mathematical phantoms --
2.3. Voxel-based phantoms --
2.4. BREP phantoms --
2.5. Summary and future perspectives 3. Overview of computational mouse models --
3.1. Introduction --
3.2. Construction of computational mouse models --
3.3. History of computational mouse models --
3.4. Simulation tools used with the computational mouse models --
3.5. Applications of computational mouse models --
3.6. Summary 4. Overview of computational rat models --
4.1. Introduction --
4.2. Overview of existing rat models --
4.3. Development and application of HUST computational rat models --
4.4. Summary 5. Overview of computational frog models --
5.1. Introduction --
5.2. History and construction of computational frog models --
5.3. Monte Carlo simulations with computational frog models --
5.4. Summary 6. Overview of computational canine models --
6.1. Introduction --
6.2. General steps for developing canine models --
6.3. Current status of canine models --
6.4. Summary and future perspectives 7. Overview of computational rabbit models --
7.1. Introduction --
7.2. Construction of rabbit models --
7.3. Model refinement --
7.4. Examples of electromagnetic and thermal dosimetry --
7.5. Summary 8. Overview of other computational animal models --
8.1. Introduction --
8.2. Computational models of trout --
8.3. Computational models of crabs --
8.4. Computational models of flatfish --
8.5. Computational models of bees --
8.6. Computational models of deer --
8.7. Computational models of earthworms --
8.8. Computational models of ducks --
8.9. Computational models of goats --
8.10. Computational models of pigs --
8.11. Computational models of non-human primates --
8.12. Summary 9. Simulation tools used with preclinical computational models --
9.1. Introduction --
9.2. Tools used for simulation --
9.3. The Monte Carlo simulation method --
9.4. Monte Carlo packages for preclinical studies --
9.5. Comparison of performance of Monte Carlo packages part II. Applications in preclinical research. 10. Applications of computational animal models in ionizing radiation dosimetry --
10.1. Introduction --
10.2. Fundamentals of radiation dosimetry --
10.3. Applications in ionizing radiation dosimetry --
10.4. Discussion 11. Computational animal phantoms for electromagnetic dosimetry --
11.1. Introduction --
11.2. Minimal requirements for EM dosimetry --
11.3. Methods --
11.4. Outlook --
11.5. Conclusions 12. Applications of computational animal models in imaging physics research --
12.1. Introduction --
12.2. Computational animal models in imaging physics --
12.3. Applications of computational animal models in imaging physics research --
12.4. Summary and future directions 13. Applications of computational animal models in radiation therapy research --
13.1. Introduction --
13.2. Design of digital mouse phantoms --
13.3. Monte Carlo simulation platforms --
13.4. Simulation of head of accelerators and energy spectra --
13.5. Types of absorbed doses calculated in digital mouse models --
13.6. Recommendations by collaborative working groups and agencies --
13.7. Differences between human organs and digital mouse organs in radiation therapy --
13.8. Excerpts of applications in digital mouse radiotherapy/dosimetry --
13.9. Conclusions 14. Summary and future outlook --
14.1. Summary --
14.2. Future outlook --
14.3. Acknowledgement.
Series Title: IOP expanding physics.; IPEM-IOP series in physics and engineering in medicine and biology.
Responsibility: Habib Zaidi.

Abstract:

Computational Anatomical Animal Models: Methodological developments and research applications provides a comprehensive review of the history and technologies used for the development of computational small animal models with a focus on their application in preclinical imaging and experimental radiation therapy, as well as non-ionizing and ionizing radiation dosimetry calculations. It also provides an overview of the overall process involved in the design of these models, including the fundamental elements used for the construction of different types of computational models, the identification of original anatomical data, the simulation tools used for solving various computational problems and the applications of computational animal models in preclinical research. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.

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