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Computing for Comparative Microbial Genomics : Bioinformatics for Microbiologists.

Author: Unspecified.; Trudy M Wassenaar; Stefano Borini
Publisher: London : Springer London, 2009.
Series: Computational biology, 8.
Edition/Format:   eBook : Document : English
Summary:
The major difficulty many microbiologists face is simply that of too much information. As a result of sequencing technologies becoming so economical, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. This accessible text/reference provides a coherent set of tools and a methodological framework for comparing raw DNA sequences and  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Unspecified.; Trudy M Wassenaar; Stefano Borini
ISBN: 1849967636 9781849967631 1848002548 9781848002548
OCLC Number: 990607862
Language Note: English.
Description: 1 online resource (271 pages)
Contents: Introductions --
Sequences as Biological Information: Cells Obey the Laws of Chemistry and Physics --
Bioinformatics for Microbiologists: An Introduction --
Microbial Genome Sequences: A New Era in Microbiology --
An Overview of Genome Databases --
The Challenges of Programming: A Brief Introduction --
Comparative Genomics --
Methods to Compare Genomes The First Examples --
Genomic Properties: Length, Base Composition and DNA Structures --
Word Frequencies and Repeats --
Transcriptomics and Proteomics --
Transcriptomics: Translated and Untranslated RNA --
Expression of Genes and Proteins --
Of Proteins, Genomes, and Proteomes --
Microbial Communities --
Microbial Communities: Core and Pan-Genomics --
Metagenomics of Microbial Communities --
Evolution of Microbial Communities; or, On the Origins of Bacterial Species.
Series Title: Computational biology, 8.
Other Titles: Computing for Comparative Microbial Genomics : Bioinformatics for Microbiologists
Computational Biology, Volume 8

Abstract:

The problem many microbiologists face is simply that of too much information. Built around teaching computational and bioinformatic methodology, this book details published methods for comparing  Read more...

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From the reviews:"It is a very well-written review of genomics and proteomics of microbes, and makes convincing arguments for the practicality of applying bioinformatics to the study of communities Read more...

 
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