Cross-over trials in clinical research
This text look at cross-over trials which are experiments in which subjects, whether patients or healthy volunteers, are each given a number of treatments with the object being to study the differences between these treatments. They are used extensively in clinical research.
Print Book, English, 2002
John Wiley and Sons, West Sussex, 2002
Preface to the Second Edition. Preface to the First Edition. 1. Introduction. 2. Some Basic Considerations Concerning Estimation in Clinical Trials. 3. The AB/BA Design with Normal Data. 4. Other Outcomes and the AB/BA Design. 5. Normal Data from Designs with Three or More Treatments. 6. Other Outcomes from Designs with Three or More Treatments. 7. Some Special Designs. 8. Graphical and Tabular Presentation of Cross-over Trials. 9. Various Design Issues. 10. Mathematical Approaches to Carry-over. References. Author Index. Subject Index.
Previous edition: 1993