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Cyclic peptide design

Author: Gilles Goetz
Publisher: New York, NY : Humana Press, 2019.
Series: Methods in molecular biology (Clifton, N.J.), v. 2001.
Edition/Format:   eBook : Document : EnglishView all editions and formats

This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance  Read more...


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Genre/Form: Electronic books
Laboratory manuals
Additional Physical Format: (OCoLC)1086008699
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Gilles Goetz
ISBN: 9781493995042 1493995049
OCLC Number: 1105930663
Description: 1 online resource (x, 332 pages) : illustrations (some color).
Contents: 1. Design Principles for Intestinal Permeability of Cyclic Peptides Alan M. Mathiowetz 2. Strategies to Enhance Metabolic Stabilities Bhavesh Khatri, Venkateswara Rao Nuthakki, and Jayanta Chatterjee 3. Designing Cell-Permeable Macrocyclic Peptides George Appiah Kubi, Patrick G. Dougherty, and Dehua Pei 4. Computational Methods for Studying Conformational Behaviors of Cyclic Peptides Fan Jiang and Hao Geng 5. Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein-Protein Interactions Fergal Duffy, Nikunj Maheshwari, Nicolae-Viorel Buchete, and Denis Shields 6. Design of Cyclic Peptides as Protein Recognition Motifs Ye Che 7. Design and Synthetic Strategies for Helical Peptides Licheng Tu, Dongyuan Wang, and Zigang Li 8. Click Chemistry for Cyclic Peptides Drug Design Adel Ahmed Rashad 9. Frontier between Cyclic Peptides and Macrocycles Philipp Ermert, Anatol Luther, Peter Zbinden, and Daniel Obrecht 10. Building upon Nature's Framework: Overview of Key Strategies towards Increasing Drug-Like Properties of Natural Product Cyclopeptides and Macrocycles Maria-Jesus Blanco 11. Design of Oxytocin Analogs Kazimierz Wisniewski 12. DNA-Encoded Macrocyclic Peptide Library Zhengrong Zhu, Alex Shaginian, LaShadric C. Grady, Christopher P. Davie, Kenneth Lind, Sandeep Pal, Praew Thansandote, and Graham L. Simpson 13. Peptide Display Technologies Anthony Pitt and Zeke Nims 14. Discovery of Functional Macrocyclic Peptides by Means of the RaPID System Christos Tsiamantas, Manuel E. Otero-Ramirez, and Hiroaki Suga 15. Genetic Selections with SICLOPPS Libraries: Towards the Identification of Novel Protein-Protein Interaction Inhibitors and Chemical Tools Francisco Castillo and Ali Tavassoli
Series Title: Methods in molecular biology (Clifton, N.J.), v. 2001.
Responsibility: edited by Gilles Goetz.


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