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Dejerine-Roussy syndrome from thalamic metastasis treated with stereotactic radiosurgery
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Dejerine-Roussy syndrome from thalamic metastasis treated with stereotactic radiosurgery

Author: Rajal A Patel; James P Chandler; Sarika Jain; Mahesh Gopalakrishnan; Sean Sachdev Affiliation: Department of Medicine, Division of Oncology, Northwestern University Robert H. Lurie Comprehensive Cancer Center, 676 N. St Clair, Suite 850, Chicago, IL 60611, USA
Edition/Format: Article Article : English
Publication:Journal of Clinical Neuroscience, v44 (October 2017): 227-228
Summary:
Dejerine-Roussy syndrome (central thalamic pain) is associated with damage to the ventral posterior sensory nuclei of the thalamus. We report a patient with breast cancer who developed contralateral hemibody paresthesias and dysesthesias. MR imaging revealed limited volume intracranial metastatic disease including a right posterior thalamic lesion. Stereotactic radiosurgery was utilized to selectively treat the  Read more...
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Document Type: Article
All Authors / Contributors: Rajal A Patel; James P Chandler; Sarika Jain; Mahesh Gopalakrishnan; Sean Sachdev Affiliation: Department of Medicine, Division of Oncology, Northwestern University Robert H. Lurie Comprehensive Cancer Center, 676 N. St Clair, Suite 850, Chicago, IL 60611, USA
ISSN:0967-5868
Language Note: English
Unique Identifier: 7065358380
Awards:

Abstract:

Dejerine-Roussy syndrome (central thalamic pain) is associated with damage to the ventral posterior sensory nuclei of the thalamus. We report a patient with breast cancer who developed contralateral hemibody paresthesias and dysesthesias. MR imaging revealed limited volume intracranial metastatic disease including a right posterior thalamic lesion. Stereotactic radiosurgery was utilized to selectively treat the lesion while preserving the remaining thalamus. Two months following treatment, the patient reported vastly improved to complete resolution of her sensory symptoms. This is the first reported case of thalamic tumor directed radiosurgical treatment leading to resolution of central neuropathic pain.

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