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Dermal absorption models in toxicology and pharmacology

Author: Jim E Riviere
Publisher: Boca Raton, FL : Taylor & Francis, 2006.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
This book reviews the basic structure and function of skin relative to absorption phenomenon. It focuses on how experiments are conducted and how the data is analyzed. It discusses membrane coated fiber technique to assess absorption, the skin component of PBPK models, and in vitro model systems with an intact vasculature. It covers how the data that quantifies dermal absorbtion is actually applied to the risk  Read more...
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Document Type: Book
All Authors / Contributors: Jim E Riviere
ISBN: 9780415700368 0415700361
OCLC Number: 999457642
Description: 374 pages : illustrations ; 24 cm
Contents: Structure and Function of Skin, N.A. Monteiro-RiviereIn Vitro Diffusion Cell Studies, R.L. BronaughPerfused Skin Models, J.E. RiviereIn Vivo Models, F. Muhammad and J.E. RiviereA Novel System Coefficient Approach for Systematic Assessment of Dermal Absorption from Chemical Mixtures, X.-R. Xia, R.E. Baynes, and J.E. RiviereBiologically Based Pharmacokinetic and Pharmacodynamic Models of the Skin, J.N. McDougal, Y. Zheng, Q. Zhang, and R. ConollyThe Prediction of Skin Permeability Using Quantitative Structure-Activity Relationship Methods, M.T.D. CroninHow Dermal Absorption Estimates Are Used in Risk Assessment, K.A. Walters and K. R. BrainGulf War Syndrome: Risk Assessment Case Study, R.E. BaynesEstimating the Absorption of Volatile Compounds Applied to Skin, G.B. KastingModeling Dermal Absorption from Soils and Powders Using Stratum Corneum Tape Stripping In Vivo, A.L. Bunge, G.D. Touraille, J.-P. Marty, and R. H. GuyAssessing Efficacy of Penetration Enhancers, B.M. Medi, S. Singh, and J. SinghEffects of Dermal Blood Flow, Lymphatics, and Binding as Determinants of Dermal Clearance, Percutaneous Absorption, and Tissue Distribution, S.E. Cross and M.S. RobertsChemical Mixtures, J.E. RiviereAnimal Models: A Comparison of Permeability Coefficients for Excised Skin from Humans and Animals, B.E. Vecchia and A.L. BungeAppendicesIndex
Responsibility: ed. by Jim E. Riviere.

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