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Genre/Form: | Academic theses |
---|---|
Material Type: | Document, Thesis/dissertation, Internet resource |
Document Type: | Internet Resource, Computer File |
All Authors / Contributors: |
Deena Lala; University of Waterloo. Department of Kinesiology. |
OCLC Number: | 827756715 |
Notes: | "A thesis presented to the University of Waterloo in fulfillment of the thesis requirement for the degree of Master of Science in Kinesiology." Title from title page image. |
Description: | 1 online resource (xi, 160 pages) : illustrations (chiefly color), forms (some color) |
Responsibility: | by Deena Lala. |
Abstract:
Background/Objectives: Low areal bone mineral density (aBMD) of the hip and knee region has been associated with fracture risk in individuals with SCI; however the contribution of bone micro-architecture to fracture risk has not been evaluated. The primary objective of this study was to determine whether a relationship exists between indices of bone strength (aBMD at the distal femur and proximal tibia; trabecular vBMD; average hole size, HA; cortical thickness, CTh; buckling ratio, BR; cross-sectional moment of inertia, CSMI; and polar moment of inertia, PMI) and potential fracture risk factors (gender, age, bisphosphonate use, time post-injury, fractures, and completeness of injury). The secondary objectives were to 1) determine whether indices of bone strength can discriminate between SCI patients with and without fragility fractures; 2) determine if these indices of bone strength correlate with the number of fractures sustained; and 3) determine the proportion of individuals with SCI who have a trabecular vBMD at the ultra-distal tibia that is below 72mg/cm3.
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