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DNA polymerases : discovery, characterization, and functions in cellular DNA transactions

Author: Ulrich Hübscher
Publisher: Hackensack, NJ : World Scientific, ©2010.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex physiological processes of DNA replication and repair. Besides the tasks in vivo, DNA polymerases are the workhorses in numerous biotechniques such as polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics, as well as techniques to  Read more...
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Genre/Form: Electronic books
Electronic book
Additional Physical Format: Print version:
DNA polymerases.
Hackensack, NJ : World Scientific, ©2010
(OCoLC)664318525
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Ulrich Hübscher
ISBN: 9789814299176 9814299170
OCLC Number: 670430601
Description: 1 online resource (xv, 321 pages) : illustrations, portraits
Contents: History and discovery of DNA polymerases --
DNA polymerases in the three kingdoms of life: bacteria, archaea and eukaryotes --
Structural and functional aspects of the prokaryotic and archaea DNA polymerase families --
Structural and functional aspects of the eukaryotic DNA polymerase families --
Global functions of DNA polymerases --
Viral DNA polymerases --
Synthetic evolution of DNA polymerases with novel properties --
DNA polymerases and diseases --
DNA polymerases and chemotherapy.
Responsibility: Ulrich Hübscher [and others].

Abstract:

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex physiological processes of DNA replication and repair.  Read more...

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